Structural alterations of the hippocampal formation of adrenalectomized rats: An unbiased stereological study

Journal of Neurocytology

Volumn 26, Issue 6, 1997, Pages 423-438

  Sousa, N ^a   Madeira, M D ^a   Paula Barbosa, M M ^a  

^a Porto School of Nursing   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROPEPTIDE Y;

ADRENALECTOMY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SIZE; CELL LOSS; CONTROLLED STUDY; DENTATE GYRUS; HIPPOCAMPUS; MALE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOMETRY;

ADRENALECTOMY; ANIMALS; ASTROCYTES; BODY WEIGHT; CELL COUNT; DENTATE GYRUS; GAMMA-AMINOBUTYRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERNEURONS; MALE; NERVE DEGENERATION; NEUROPEPTIDE Y; ORGAN SIZE; RATS; RATS, WISTAR; SOMATOSTATIN;

ANIMALIA;

EID: 0030762413     PISSN: 03004864     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018573105987     Document Type: Article

References (60)

1. ADEM, A., ISLAM, A., BOGDANOVIC, N., CARLSTROM, K. & WINBLAD, B. (1994) Loss of neurones after long-term adrenalectomy in the adult rat hippocampal formation. NeuroReport 5, 2285-8.
2. AHIMA, R. S. & HARLAN, R. E. (1990) Charting of type II glucocorticoid receptor-like immunoreactivity in the rat central nervous system. Neuroscience 39, 579-604.
3. AHIMA, R. S., KROZOWSKI, Z. & HARLAN, R. E. (1991) Type I corticosteroid receptor-like immunoreactivity in the rat CNS: distribution and regulation by corticosteroids. Journal of Comparative Neurology 313, 522-38.
4. ALTMAN, J. & BAYER, S.A. (1990) Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods. Journal of Comparative Neurology 301, 365-81.
5. AMARAL, D. G. & WITTER, M. P. (1989) The three-dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 31, 571-91.
6. ANDRADE, J. P. & PAULA-BARBOSA, M. M. (1996) Protein malnutrition alters the cholinergic and GABAergic systems of the hippocampal formation of the adult rat: an immunocytochemical study. Neuroscience Letters 211, 211-5.
7. ANDRADE, J. P., FERNANDO, P. M., MADEIRA, M. D., PAULA-BARBOSA, M. M., CADETE-LEITE, A. & ZIMMER, J. (1992) Effects of chronic alcohol consumption and withdrawal on the somatostatin-immunoreactive neurons of the rat hippocampal dentate hilus. Hippocampus 2, 65-72.
8. ANDRADE, J. P., MADEIRA, M. D. & PAULA-BARBOSA, M. M. (1995) Effects of long-term malnutrition and rehabilitation on the hippocampal formation of the adult rat. A morphometric study. Journal of Anatomy 187, 379-93.
9. ARMSTRONG, J. N., McINTYRE, D. C., NEUBORT, S. & SLOVITER, R. S. (1993) Learning and memory after adrenalectomy-induced hippocampal dentate granule cell degeneration in the rat. Hippocampus 3, 359-71.
10. AUS DER MÜHLEN, K. & OCKENFELS, H. (1969) Morphologische Veränderungen im Diencephalon und Telencephalon nach Störugen des Regelkreises Adenohypophyse-Nebennierenrinde. III. Ergebnisse beim Meerschweinchen nach Verabreichung von Cortison und Hydrocortison. Zeitschrift für Zellforschung 93, 126-41.
11. BIGNAMI, A. & DAHL, D. (1974) Astrocyte-specific protein and neuroglial differentiation. An immunofluorescence study with antibodies to glial fibrillary acidic protein. Journal of Comparative Neurology 153, 27-38.
12. CONRAD, C. D. & ROY, E. J. (1993) Selective loss of hippocampal granule cells following adrenalectomy: implications for spatial memory. Journal of Neuroscience 13, 2582-90.
13. CONRAD, C. D. & ROY, E. J. (1995) Dentate gyrus destruction and spatial learning impairment after corticosteroid removal in young and middle-aged rats. Hippocampus 5, 1-15.
14. DE KLOET, E. R. (1991) Brain corticosteroid receptor balance and homeostatic control. Frontiers in Neuroendocrinology 12, 95-164.
15. FELDMAN, S. & CONFORTI, N. (1980) Participation of the dorsal hippocampus in the glucocorticoid feedback effect on adrenocortical activity. Neuroendocrinology 30, 52-5.
16. FUKUI, K., UTSUMI, H., TAMADA, Y., KAKAJIMA, T. & IBATA, Y. (1996) Selective increase in astrocytic elements in the rat dentate gyrus after chronic toluene exposure studied by GFAP immunocytochemistry and electron microscopy. Neuroscience Letters 203, 85-8.
17. GAGE, F. H., OLEJNICZAK, P. & ARMSTRONG, D. M. (1988) Astrocytes are important for sprouting in the septohippocampal circuit. Experimental Neurology 102, 2-13.
18. GALL, C., ROSE, G. & LYNCH, G. (1979) Proliferative and migratory activity of glial cells in the partially deafferented hippocampus. Journal of Comparative Neurology 183, 539-50.
19. GOULD, E., WOOLEY, C. S. & McEWEN, B. S. (1990) Short-term glucocorticoid manipulations affect neuronal morphology and survival in the adult dentate gyrus. Neuroscience 37, 367-75.
20. GUNDERSEN, H. J. G. (1986) Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. Journal of Microscopy 143, 3-45.
21. GUNDERSEN, H. J. G., BENDSTEN, T. F., KORBO, L., MARCUSSEN, N., MØLLER, A., NIELSEN, K., NYENGAARD, J. R., PAKKENBERG, B., SØRENSEN, F. B., VESTERBY, A. & WEST, M. J. (1988a) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. Acta Pathologica Microbiologica et Immunologica Scandinavica 96, 379-94.
22. GUNDERSEN, H. J. G., BAGGER, P., BENDSTEN, T. F., EVANS, S. M., KORBO, L., MARCUSSEN, N., MØLLER, A., NIELSEN, K., NYENGAARD, J. R., PAKKENBERG, B., SØRENSEN, F. B., VESTERBY, A. & WEST, M. J. (1988b) The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. Acta Pathologica Microbiologica et Immunologica Scandinavica 96, 857-81.
23. HERMAN, J. P. & WATSON, S. J. (1995) Stress regulation of mineralocorticoid receptor heteronuclear RNA in rat hippocampus. Brain Research 677, 243-9.
24. HERMAN, J. P., SCHAFFER, M. K. H., YOUNG, E. A., THOMPSON, R., DOUGLAS, J., AKIL, H. & WATSON, S. J. (1989) Evidence for hippocampal regulation of neuroendocrine neurons of the hypothalamo pituitary adrenocortical axis. Journal of Neuroscience 9, 3072-82.
25. ISLAM, A., HENRIKSON, B., MOHAMMED, A., WINBLAD, B. & ADEM, A. (1995) Behavioural deficits following long-term adrenalectomy. Nenroscience Letters 194, 49-52.
26. JAARSMA, D., POSTEMA, F. & KORF, J. (1992) Time course and distribution of neuronal degeneration in the dentate gyrus of rat after adrenalectomy: a silver impregnation study. Hippocampus 2, 143-50.
27. JØRGENSEN, M. B., FINSEN, B. R., JENSEN, M. B., CASTELLANO, B., DIEMER, N. H. & ZIMMER, J. (1993) Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus. Experimental Neurology 120, 70-88.
28. KÖHLER, C., ERIKSON, L., DAVIES, S. & CHAN-PALAY, V. (1986) Neuropeptide Y innervation of the hippocampal region in the rat and monkey brain. Journal of Comparative Neurology 244, 384-400.
29. KRUGGERS, H. J., MEDEMA, R. M., POSTEMA, F. & KORF, J. (1994) Induction of glial fibrillary acid protein immunoreactivity in the rat dentate gyrus after adrenalectomy: comparison with neurodegenerative changes using silver impregnation. Hippocampus 4, 307-14.
30. LANDFIELD, P. W., BASKIN, R. K. & PITLER, T. A. (1981) Brain aging correlates: retardation by hormonal-pharmacological treatments. Science 241, 581-4.
31. LING, E. A., PATERSON, J. A., PRIVAT, A., MORI, S. & LEBLOND, C. P. (1973) Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats. Journal of Comparative Neurology 149, 43-72.
32. MADEIRA, M. D., SOUSA, N., LIMA-ANDRADE, M. T., CALHEIROS, F., CADETE-LEITE, A. & PAULA-BARBOSA, M. M. (1992) Selective vulnerability of the hippocampal pyramidal neurons to hypothyroidism in male and female rats. Journal of Comparative Neurology 322, 501-18.
33. MADEIRA, M. D., SOUSA, N., SANTER, R. M., PAULA-BARBOSA, M. M. & GUNDERSEN, H. J. G. (1995) Age and sex do not affect the volume, cell numbers, or cell size of the suprachiasmatic nucleus of the rat: an unbiased stereological study. Journal of Comparative Neurology 361, 585-601.
34. MAEHLEN, J. & TORVIK, A. (1990) Necrosis of granule cells of hippocampus in adrenocortical failure. Acta Neuropathologica 80, 85-7.
35. MAYHEW, T. M. (1992) A review of recent advances in stereology for quantifying neural structure. Journal of Neurocytology 21, 313-28.
36. MAYHEW, T. M. & GUNDERSEN, H. J. G. (1996) "If you assume, you can make an ass out of u and me": a decade of the disector for stereological counting of particles in 3D space. Journal of Anatomy 188, 1-15.
37. McEWEN, B. S. & GOULD, E. (1990) Adrenal steroid influences on the survival of hippocampal neurons. Biochemical Pharmacology 40, 2393-402.
38. McEWEN, B. S., DE KLOET, E. R. & ROSTENE, W. (1986) Adrenal steroid receptors and actions in the nervous system. Physiological Reviews 66, 1121-88.
39. McNEILL, T. H., MASTERS, J. N. & FINCH, C. E. (1991) Effect of chronic adrenalectomy on neuron loss and distribution of sulphated glycoprotein-2 in the dentate gyrus of prepubertal rats. Experimental Neurology 111, 140-4.
40. O'CALLAGHAN, J. P., BRINTON, R. E. & McEWEN, B. S. (1989) Glucocorticoids regulate the concentration of glial fibrillary acidic protein throughout the brain. Brain Research 494, 159-61.
41. PAULA-BARBOSA, M. M., BRANDÃO, F., MADEIRA, M. D. & CADETE-LEITE, A. (1993) Structural changes in the hippocampal formation after long-term alcohol consumption and withdrawal in the rat. Addiction 88, 237-47.
42. REUL, J. M. H. & DE KLOET, E. R. (1985) Two receptor systems for corticosterone in the rat brain: microdistribution and differential occupation. Endocrinology 117, 2505-11.
43. REUL, J. M. H., VAN DER BOSCH, F. R. & DE KLOET, E. R. (1987) Relative occupation of type-I and type-II corticosteroid receptors in the brain following stress and dexamethasone treatment: functional implications. Journal of Endocrinology 115, 459-67.
44. ROSE, G., LYNCH, G. & COTMAN, W. (1976) Hypertrophy and redistribution of astrocytes in the deafferented dentate gyrus. Brain Research Bulletin 1, 87-92.
45. ROY, E. J., LYNN, D. M. & BEMM, C. W. (1990) Individual variations in hippocampal dentate degeneration following adrenalectomy. Behavioural Neural Biology 54, 330-6.
46. SAPOLSKY, R. M., KREY, L. C. & McEWEN, B. S. (1985) Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging. Journal of Neuroscience 5, 1222-7.
47. SAPOLSKY, R. M., KREY, L. C. & McEWEN, B. S. (1986) The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocrine Reviews 7, 284-301.
48. SAPOLSKY, R. M., STEIN-BEHRENS, B. A. & ARMANINI, M. P. (1991) Long-term adrenalectomy causes loss of dentate gyrus and pyramidal neurons in the adult hippocampus. Experimental Neurology 114, 246-9.
49. SCHMIDT-KASTNER, R. & FREUND, T. (1991) Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40, 599-636.
50. SLOVITER, R. S. & NILAVER, G. (1987) Immunocytochemical localization of GABA-, cholecystokinin-, vasoactive intestinal polypeptide-, and somatostatin-like immunoreactivity in the area denteada and hippocampus of the rat. Journal of Comparative Neurology 252, 42-60.
51. SLOVITER, R. S., VALIQUETTE, G., ABRAMS, G. M., RONK, E. C., SOLLAS, A. L., PAUL, L. A. & NEUBORT, S. (1989) Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy. Science 243, 535-8.
52. SLOVITER, R. S., DEAN, E. & NEUBORT, S. (1993a) Electron microscopic analysis of adrenalectomy-induced hippocampal granule cell degeneration in the rat: apoptosis in the adult central nervous system. Journal of Comparative Neurology 330, 337-51.
53. SLOVITER, R. S., SOLLAS, A. L., DEAN, E. & NEUBORT, S. (1993b) Adrenalectomy-induced granule cell degeneration in the rat hippocampal dentate gyrus: characterization of an in vivo model of controlled neuronal death. Journal of Comparative Neurology 330, 324-36.
54. SQUIRE, L. R. (1992) Memory and the hippocampus: a synthesis from findings in rats, monkeys and humans, Psychological Reviews 99, 195-231.
55. STERIO, D. C. (1984) The unbiased estimation of number and sizes of arbitrary particles using the disector. Journal of Microscopy 134, 127-36.
56. UNO, H., TARARA, R., ELSE, J., SULEMAN, M. & SAPOLSKY, R. (1989) Hippocampal damage associated with prolonged and fatal stress in primates. Journal of Neuroscience 9, 1705-11.
57. VAHER, P. R., LUINE, V. N., GOULD, E. & McEWEN, B. S. (1994) Effects of adrenalectomy on spatial memory performance and dentate gyrus morphology. Brain Research 656, 71-8.
58. WEST, M. J., SLOMIANKA, L. & GUNDERSEN, H. J. G. (1991) Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anatomical Record 231, 482-97.
59. WOODSON, W., NITECKA, L. & BEN-ARI, Y. (1989) Organization of the GABAergic system in the rat hippocampal formation: a quantitative immunocytochemical study. Journal of Comparative Neurology 280, 254-71.
60. WOOLEY, C. S., GOULD, E., SAKAI, R. R., SPENCER, R. L. & McEWEN, B. S. (1991) Effects of aldosterone or RU28362 treatment on adrenalectomy-induced cell death in the dentate gyrus of the adult rat. Brain Research 554, 312-5.