Selective increase in astrocytic elements in the rat dentate gyrus after chronic toluene exposure studied by GFAP immunocytochemistry and electron microscopy

Neuroscience Letters

Volumn 203, Issue 2, 1996, Pages 85-88

  Fukui, Kenji ^a   Utsumi, Hirohiko ^a   Tamada, Yoshitaka ^a   Nakajima, Teruo ^a   Ibata, Yasuhiko ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Astrocyte; Chronic toluene exposure; Dentate gyrus; Electron microscopy; Glial fibrillary acidic protein (GFAP) immunocytochemistry; Rat brain

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; TOLUENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DENTATE GYRUS; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030031331     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)12270-2     Document Type: Article

References (22)

1. Arlien-Søborg, P., Solvent Neurotoxicity, CRC Press, Boca Raton, 1992.
2. Baelum, J., Human solvent exposure: factors influencing the pharmacokinetics and acute toxicity, J. Pharmacol. Toxicol., 1 (1991) 1-36.
3. Baker, A.B. and Tichy, F.Y., The effects of the organic solvents and industrial poisoning on the central nervous system, Res. Publ Assoc. Nerv. Ment. Dis., 32 (1953) 475-505.
4. Fukui, K., Utsumi, H., Kawashima, Y., lizumi, H. and Nakajima, T., Selective increase of nitric oxide synthase (NOS) staining in the rat brain induced by chronic toluene inhalation: quantitative morphometric NADPH-diaphorase enzyme histochemistry, Alcohol Alcoholism Clin. Exp. Res. (Abstract), (1994) 56A.
5. Furukawa, S., Furukawa, Y., Satoyoshi, E. and Hayashi, K., Synthesis and secretion of nerve growth factor by mouse astroglia cells in culture, Biochem. Biophys. Res. Commun., 136 (1986) 57-63.
6. Fuxe, K., Andersson, K., Nilsen, O.G., Toftgard, R., Eneroth, P. and Gustafsson, J.-A., Toluene and telencephalic dopamine: selective reduction of amine turnover in discrete DA nerve terminal systems of the anterior caudate nucleus by low concentration of toluene, Toxicol. Lett., 12 (1982), 115-123.
7. Gosper, Jr., S.M. and Calaban, M.J., Central nervous system distribution of inhaled toluene, Fundam. Appl. Toxicol., 11 (1988), 540-545.
8. Huang, J., Kato, K., Shibata, E., Asaeda, N. and Takeuchi, Y., Nerve-specific marker proteins as indicators of organic solvent neurotoxicity, Environ. Res., 63 (1993) 82-87.
9. IIzumi, H., Utsumi, H., Kawashima, Y., Fukui, K. and Nakajima, T., Functional morphological studies on the action of toluene in the rat central nervous system, Jpn. J. Psychiat. Neurol., 47 (1993) 733-734.
10. Kesslak, J.P., Nieto-Samperdro, M., Globus, J. and Cotman, C.W., Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation, Exp. Neurol., 93 (1086) 377-390.
11. Kimelberg, H.K. and Katz, D.M., High-affinity uptake of serotonin into immunocytochemically identified astrocytes, Science, 228 (1985) 889-891.
12. Kornfeld, M., Moser, B., Moser, H.W., Kleinschmidt-DeMasters, B., Norte, K. and Pheips, A., Solvent vapor abuse leukoencephalopathy: comparison to adrenoleukodystrophy, J. Neuropathol. Exp. Neurol., 53 (1994) 389-398.
13. Ladefoged, O., Strange, P., Moller, A., Ostergaard, G., Larsen, J.J. and Arlien-Soborg, P, Irreversible effects in rats of toluene (inhalation) exposure for six months, Pharmacol. Toxicol., 68 (1991) 384-390.
14. Mathewson, A.J. and Berry, M., Observation on astrocyte response to a cerebral stab wound in adult rats, Brain Res., 327 (1985) 61-69.
15. Mattia, C.J., LeBel, C.P. and Bondy, S.C., Effects of toluene and its metabolites on cerebral reactive oxygen species generation, Biochem. Pharmacol., 42 (1991) 879-882.
16. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1982.
17. Rasband, W., NIH Image 1.55, NIH Res. Serv. Branch, 1994.
18. Rosenberg, N.L., Kleinschmidt-DeMasters, B.K., Davis, K.A., Dreisbach, J.N., Hormes, J.T. and Filley, C.M., Toluene abuse causes diffuse central nervous system white matter changes, Ann. Neurol., 23 (1988) 611-614.
19. Slomianka, L., Edelfors, S., Ravn-Jonsen, A., Rungby, J., Danscher, G. and West, M.J., The effect of low-level toluene exposure on the developing hippocampal region of the rat: histological evidence and volumetric findings, Toxicology, 62 (1990) 189-202.
20. Toftgard, R., Nilsen, O.G. and Gustafsson, J.A., Changes in rat liver microsomal cytochrome P-450 and enzymatic activities after inhalation of n-hexane, xylene, methyl ethyl ketone and methyl-chloroform for 4 weeks, Scand. J. Work. Environ. Health, 7 (1981) 31-37.
21. Vazoquez-Nin, G., Zipitria, D., Echeverria, O.M., Bermudez-Rattoni, F., Cruz-Morales, S.E. and Prado-Alcala, R.A., Early neuronal alterations caused by experimental thinner inhalation in young rats, Neurobehav. Toxicol., 2 (1980) 25-30.
22. Walsh, T. and Emerich, D.F., The hippocampus as common target of neurotoxic agents, Toxicology, 49 (1988) 137-140.