메뉴 건너뛰기




Volumn 74, Issue 1, 1997, Pages 20-30

Quantitative analysis of endoplasmic reticulum and cytochrome P-450 in hepatocytes from rats injected with methylcholanthrene

Author keywords

Cytochrome P 450; Endoplasmic reticulum; Liver; Methylcholanthrene

Indexed keywords

3 METHYLCHOLANTHRENE; CYTOCHROME P450; UNSPECIFIC MONOOXYGENASE;

EID: 0030761333     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (37)
  • 1
    • 0028820775 scopus 로고
    • Endoplasmic reticulum proliferates without an increase in cytochrome P-450 in hepatocytes of mice treated with phenobarbital and cobalt chloride
    • Amatsu, T., J. Watanabe, Y. Asaka, S. Kanamura: Endoplasmic reticulum proliferates without an increase in cytochrome P-450 in hepatocytes of mice treated with phenobarbital and cobalt chloride. Eur. J. Cell Biol. 68, 256-262 (1995).
    • (1995) Eur. J. Cell Biol. , vol.68 , pp. 256-262
    • Amatsu, T.1    Watanabe, J.2    Asaka, Y.3    Kanamura, S.4
  • 2
    • 0019732980 scopus 로고
    • An immunohistochemical study on the localization and distributions of phenobarbital- and 3-methylcholanthrene-inducible cytochrome P-450 within the livers of untreated rats
    • Baron, J., J. A. Redick, F. P. Guengerich: An immunohistochemical study on the localization and distributions of phenobarbital- and 3-methylcholanthrene-inducible cytochrome P-450 within the livers of untreated rats. J. Biol. Chem. 256, 5931-5937 (1981).
    • (1981) J. Biol. Chem. , vol.256 , pp. 5931-5937
    • Baron, J.1    Redick, J.A.2    Guengerich, F.P.3
  • 3
    • 0020084953 scopus 로고
    • Effects of 3-methylcholanthrene, β-naphthoflavone, and phenobarbital on the 3-methylcholanthrene-inducible isozyme of cytochromes P-450 within centrilobular, midzonal, and periportal hepatocytes
    • Baron, J., J. A. Redick, F. P. Guengerich: Effects of 3-methylcholanthrene, β-naphthoflavone, and phenobarbital on the 3-methylcholanthrene-inducible isozyme of cytochromes P-450 within centrilobular, midzonal, and periportal hepatocytes. J. Biol. Chem. 257, 953-957 (1982).
    • (1982) J. Biol. Chem. , vol.257 , pp. 953-957
    • Baron, J.1    Redick, J.A.2    Guengerich, F.P.3
  • 4
    • 0017831790 scopus 로고
    • Fluorometric and chromatographic methods for measuring microsomal biphenyl hydroxylation
    • Burke, M. D., R. A. Prough: Fluorometric and chromatographic methods for measuring microsomal biphenyl hydroxylation. Methods Enzymol. 52, 399-407 (1978).
    • (1978) Methods Enzymol. , vol.52 , pp. 399-407
    • Burke, M.D.1    Prough, R.A.2
  • 5
    • 0019551730 scopus 로고
    • "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • Burnette, W. N.: "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112, 195-203 (1981).
    • (1981) Anal. Biochem. , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 6
    • 0022971307 scopus 로고
    • Induction of microsomal P-450 enzymes: The first Bernard B. Brodie lecture at Pennsylvania State University
    • Conney, A. H.: Induction of microsomal P-450 enzymes: the first Bernard B. Brodie lecture at Pennsylvania State University. Life Sci. 39, 2493-2518 (1986).
    • (1986) Life Sci. , vol.39 , pp. 2493-2518
    • Conney, A.H.1
  • 7
    • 0016642871 scopus 로고
    • A simple technique for eliminating interference by detergents in the Lowry method of protein determination
    • Dulley, J. R., P. A. Grieve: A simple technique for eliminating interference by detergents in the Lowry method of protein determination. Anal. Biochem. 64, 136-141 (1975).
    • (1975) Anal. Biochem. , vol.64 , pp. 136-141
    • Dulley, J.R.1    Grieve, P.A.2
  • 8
    • 0020604607 scopus 로고
    • Effects of inhibiting hepatocarcinogenesis upon the early fine structural changes induced in rat hepatocytes by 3′-methyl-4-dimethylaminoazobenzene
    • Flaks, B., A. Flaks, H. Jones, A. Milsom: Effects of inhibiting hepatocarcinogenesis upon the early fine structural changes induced in rat hepatocytes by 3′-methyl-4-dimethylaminoazobenzene. Carcinogenesis 4, 1139-1145 (1983).
    • (1983) Carcinogenesis , vol.4 , pp. 1139-1145
    • Flaks, B.1    Flaks, A.2    Jones, H.3    Milsom, A.4
  • 9
    • 0009627611 scopus 로고
    • Morphological changes in the liver accompanying stimulation of microsomal drug metabolizing enzyme activity by phenobarbital, chlordane, benzpyrene or methylcholanthrene in rats
    • Fouts, J. R., L. A. Rogers: Morphological changes in the liver accompanying stimulation of microsomal drug metabolizing enzyme activity by phenobarbital, chlordane, benzpyrene or methylcholanthrene in rats. J. Pharmacol. Exp. Ther. 147, 112-119 (1965).
    • (1965) J. Pharmacol. Exp. Ther. , vol.147 , pp. 112-119
    • Fouts, J.R.1    Rogers, L.A.2
  • 10
    • 0020955222 scopus 로고
    • Microbiochemical approach to liver cell heterogeneity around terminal hepatic venules
    • Hildebrand, R.: Microbiochemical approach to liver cell heterogeneity around terminal hepatic venules. Histochemistry 78, 539-544 (1983).
    • (1983) Histochemistry , vol.78 , pp. 539-544
    • Hildebrand, R.1
  • 11
    • 0021179667 scopus 로고
    • Quantitative analysis of smooth endoplasmic reticulum proliferation in hepatocytes of early postnatal and adult mice treated with phenobarbital
    • Kanai, K., S. Kanamura, M. Asada-Kubota, J. Watanabe, M. Oka: Quantitative analysis of smooth endoplasmic reticulum proliferation in hepatocytes of early postnatal and adult mice treated with phenobarbital. Gastroenterology 87, 1131-1137 (1984).
    • (1984) Gastroenterology , vol.87 , pp. 1131-1137
    • Kanai, K.1    Kanamura, S.2    Asada-Kubota, M.3    Watanabe, J.4    Oka, M.5
  • 13
    • 0014274040 scopus 로고
    • A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells
    • Loud, A. V.: A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells. J. Cell Biol. 37, 27-46 (1968).
    • (1968) J. Cell Biol. , vol.37 , pp. 27-46
    • Loud, A.V.1
  • 14
    • 0021244599 scopus 로고
    • A biochemical and electron microscopic study of changes in the content of cytochrome P-450 in rat liver after cessation of treatment with phenobarbital, β-naphthoflavone or 3-methylcholanthrene
    • Masaki, R., S. Matsuura, Y. Tashiro: A biochemical and electron microscopic study of changes in the content of cytochrome P-450 in rat liver after cessation of treatment with phenobarbital, β-naphthoflavone or 3-methylcholanthrene. Cell Struct. Funct. 9, 53-66 (1984).
    • (1984) Cell Struct. Funct. , vol.9 , pp. 53-66
    • Masaki, R.1    Matsuura, S.2    Tashiro, Y.3
  • 15
    • 0025323155 scopus 로고
    • Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents
    • Murray, M., G. F. Reidy: Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents. Pharmacol. Rev. 42, 85-101 (1990).
    • (1990) Pharmacol. Rev. , vol.42 , pp. 85-101
    • Murray, M.1    Reidy, G.F.2
  • 16
    • 0015042396 scopus 로고
    • Role of rough and smooth microsomes in the biosynthesis of microsomal membranes
    • Omura, T., Y. Kuriyama: Role of rough and smooth microsomes in the biosynthesis of microsomal membranes. J. Biochem. 69, 651-658 (1971).
    • (1971) J. Biochem. , vol.69 , pp. 651-658
    • Omura, T.1    Kuriyama, Y.2
  • 17
    • 0028104347 scopus 로고
    • Pretranslational induction of cytochrome P4501A enzymes by β-naphthoflavone and 3-methylcholanthrene occurs in different liver zones
    • Oinonen, T., S. Saarikoski, K. Husgafvel-Pursiainen, A. Hirvonen, K. O. Lindros: Pretranslational induction of cytochrome P4501A enzymes by β-naphthoflavone and 3-methylcholanthrene occurs in different liver zones. Biochem. Pharmacol. 48, 2189-2197 (1994).
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 2189-2197
    • Oinonen, T.1    Saarikoski, S.2    Husgafvel-Pursiainen, K.3    Hirvonen, A.4    Lindros, K.O.5
  • 18
    • 0020478846 scopus 로고
    • Immunochemical relatedness of rat hepatic microsomal cytochromes P-450c and P-450d
    • Reik, L. M., W. Levin, D. E. Ryan, P. E. Thomas: Immunochemical relatedness of rat hepatic microsomal cytochromes P-450c and P-450d. J. Biol. Chem. 257, 3950-3957 (1982).
    • (1982) J. Biol. Chem. , vol.257 , pp. 3950-3957
    • Reik, L.M.1    Levin, W.2    Ryan, D.E.3    Thomas, P.E.4
  • 19
    • 0027405762 scopus 로고
    • Quantitative immunohistochemistry in the rat facial nucleus with [125I]-iodinated secondary antibodies and in situ autoradiography: Non-linear binding characteristics of primary monoclonal and polyclonal antibodies
    • Raivich, G., J. Gehrmann, M. B. Graeber, G. W. Kreutzberg: Quantitative immunohistochemistry in the rat facial nucleus with [125I]-iodinated secondary antibodies and in situ autoradiography: non-linear binding characteristics of primary monoclonal and polyclonal antibodies. J. Histochem. Cytochem. 41, 579-592 (1993).
    • (1993) J. Histochem. Cytochem. , vol.41 , pp. 579-592
    • Raivich, G.1    Gehrmann, J.2    Graeber, M.B.3    Kreutzberg, G.W.4
  • 20
    • 0019161825 scopus 로고
    • Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms
    • Ryan, D. E., P. E. Thomas, W. Levin: Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms. J. Biol. Chem. 255, 7941-7955 (1980).
    • (1980) J. Biol. Chem. , vol.255 , pp. 7941-7955
    • Ryan, D.E.1    Thomas, P.E.2    Levin, W.3
  • 21
    • 0020604891 scopus 로고
    • Biological and induction effects of phenobarbital and 3-methylcholanthrene in mink (Mustela vision)
    • Shull, L. R., G. F. Rush, B. A. Olson, S. D. Sleight, R. J. Auerich, J. A. Wisniewski: Biological and induction effects of phenobarbital and 3-methylcholanthrene in mink (Mustela vision). Drug Metab. Dispos. 11, 441-445 (1983).
    • (1983) Drug Metab. Dispos. , vol.11 , pp. 441-445
    • Shull, L.R.1    Rush, G.F.2    Olson, B.A.3    Sleight, S.D.4    Auerich, R.J.5    Wisniewski, J.A.6
  • 22
    • 0017656417 scopus 로고
    • A new enzymatic method for determination of serum choline-containing phospholipids
    • Takayama, M., S. Itoh, T. Nagasaki, I. Tanimizu: A new enzymatic method for determination of serum choline-containing phospholipids. Clin. Chim. Acta 79, 93-98 (1977).
    • (1977) Clin. Chim. Acta , vol.79 , pp. 93-98
    • Takayama, M.1    Itoh, S.2    Nagasaki, T.3    Tanimizu, I.4
  • 23
    • 0020628133 scopus 로고
    • Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics
    • Thomas, P. E., L. M. Reik, D. E. Ryan, W. Levin: Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics. J. Biol. Chem. 258, 4590-4598 (1983).
    • (1983) J. Biol. Chem. , vol.258 , pp. 4590-4598
    • Thomas, P.E.1    Reik, L.M.2    Ryan, D.E.3    Levin, W.4
  • 24
    • 0026638156 scopus 로고
    • Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in liver
    • Tritscher, A. M., J. A. Goldstein, C. J. Portier, Z. McCoy, G. C. Clark, G. W. Lucier: Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in liver. Cancer Res. 52, 3436-3442 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 3436-3442
    • Tritscher, A.M.1    Goldstein, J.A.2    Portier, C.J.3    McCoy, Z.4    Clark, G.C.5    Lucier, G.W.6
  • 25
    • 0025279548 scopus 로고
    • Effect of different doses of 3-methylcholanthrene on the localization of the 3-methylcholanthrene-inducible isozymes of cytochrome P450 within the centrilobular and periportal zones of rat liver
    • Van Sliedregt, A., C. F. van Bezooijen: Effect of different doses of 3-methylcholanthrene on the localization of the 3-methylcholanthrene-inducible isozymes of cytochrome P450 within the centrilobular and periportal zones of rat liver. Biochem. Pharmacol. 39, 1703-1708 (1990).
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 1703-1708
    • Van Sliedregt, A.1    Van Bezooijen, C.F.2
  • 26
    • 0024405374 scopus 로고
    • A new microphotometric method for measurement of cytochrome P-450 in sections of liver
    • Watanabe, J., K. Kanai, S. Kanamura: A new microphotometric method for measurement of cytochrome P-450 in sections of liver. J. Histochem. Cytochem. 37, 1257-1263 (1989).
    • (1989) J. Histochem. Cytochem. , vol.37 , pp. 1257-1263
    • Watanabe, J.1    Kanai, K.2    Kanamura, S.3
  • 27
    • 0026055784 scopus 로고
    • Measurement of NADPH-ferrihemoprotein reductase content in sections of liver
    • Watanabe, J., K. Kanai, S. Kanamura: Measurement of NADPH-ferrihemoprotein reductase content in sections of liver. J. Histochem. Cytochem. 39, 1635-1643 (1991).
    • (1991) J. Histochem. Cytochem. , vol.39 , pp. 1635-1643
    • Watanabe, J.1    Kanai, K.2    Kanamura, S.3
  • 28
    • 0025798967 scopus 로고
    • An improved microphotometry system for measurement of cytochrome P-450 in hepatocyte cytoplasm
    • Watanabe, J., S. Kanamura: An improved microphotometry system for measurement of cytochrome P-450 in hepatocyte cytoplasm. J. Histochem. Cytochem. 39, 689-694 (1991).
    • (1991) J. Histochem. Cytochem. , vol.39 , pp. 689-694
    • Watanabe, J.1    Kanamura, S.2
  • 29
    • 0026510147 scopus 로고
    • Relation between cytochrome P-450 increase and endoplasmic reticulum proliferation in hepatocytes of mice treated with phenobarbital: A microphotometric and morphometric study
    • Watanabe, J., Y. Asaka, K. Kanai, S. Kanamura: Relation between cytochrome P-450 increase and endoplasmic reticulum proliferation in hepatocytes of mice treated with phenobarbital: a microphotometric and morphometric study. J. Histochem. Cytochem. 40, 353-357 (1992).
    • (1992) J. Histochem. Cytochem. , vol.40 , pp. 353-357
    • Watanabe, J.1    Asaka, Y.2    Kanai, K.3    Kanamura, S.4
  • 30
    • 0027463971 scopus 로고
    • Densities of NADPH-ferrihemoprotein reductase and cytochrome P-450 molecules in the endoplasmic reticulum membrane of rat hepatocytes
    • Watanabe, J., Y. Asaka, S. Fujimoto, S. Kanamura: Densities of NADPH-ferrihemoprotein reductase and cytochrome P-450 molecules in the endoplasmic reticulum membrane of rat hepatocytes. J. Histochem. Cytochem. 41, 43-49 (1993).
    • (1993) J. Histochem. Cytochem. , vol.41 , pp. 43-49
    • Watanabe, J.1    Asaka, Y.2    Fujimoto, S.3    Kanamura, S.4
  • 31
    • 0028363021 scopus 로고
    • Measurement of NADPH-cytochrome P-450 reductase content in rat liver sections by quantitative immunohistochemistry with a video image processor
    • Watanabe, J., Y. Asaka, T. Tanaka, S. Kanamura: Measurement of NADPH-cytochrome P-450 reductase content in rat liver sections by quantitative immunohistochemistry with a video image processor. J. Histochem. Cytochem. 42, 1161-1167 (1994).
    • (1994) J. Histochem. Cytochem. , vol.42 , pp. 1161-1167
    • Watanabe, J.1    Asaka, Y.2    Tanaka, T.3    Kanamura, S.4
  • 32
    • 0029790989 scopus 로고    scopus 로고
    • Peri- and postnatal changes in reduced nicotinamide adenine dinucleotide phosphatecytochrome P-450 reductasc content in hepatocytes of rats
    • Watanabe, J., Y. Asaka, S. Kanamura: Peri- and postnatal changes in reduced nicotinamide adenine dinucleotide phosphatecytochrome P-450 reductasc content in hepatocytes of rats. Histochem. J. 28, 505-510 (1996).
    • (1996) Histochem. J. , vol.28 , pp. 505-510
    • Watanabe, J.1    Asaka, Y.2    Kanamura, S.3
  • 33
    • 3242835346 scopus 로고    scopus 로고
    • Relationship between immunostaining intensity and antigen content in sections
    • Watanabe, J., Y. Asaka, S. Kanamura: Relationship between immunostaining intensity and antigen content in sections. J. Histochem. Cytochem. 44, 1451-1458 (1996).
    • (1996) J. Histochem. Cytochem. , vol.44 , pp. 1451-1458
    • Watanabe, J.1    Asaka, Y.2    Kanamura, S.3
  • 34
    • 0014546946 scopus 로고
    • Correlated morphometric and biochemical studies on the liver cell. I. Morphometric model, stereologic methods, and normal morphometric data for rat liver
    • Weibel, E. R., W. Stäubli, H. R. Gnägi, F. A. Hess: Correlated morphometric and biochemical studies on the liver cell. I. Morphometric model, stereologic methods, and normal morphometric data for rat liver. J. Cell Biol. 42, 68-91 (1969).
    • (1969) J. Cell Biol. , vol.42 , pp. 68-91
    • Weibel, E.R.1    Stäubli, W.2    Gnägi, H.R.3    Hess, F.A.4
  • 35
    • 0000351855 scopus 로고
    • Practical methods for biological morphometry
    • Academic Press. London
    • Weibel, E. R.: Practical methods for biological morphometry. In: Stereological Methods. 1. pp 101-161. Academic Press. London 1979.
    • (1979) Stereological Methods , vol.1 , pp. 101-161
    • Weibel, E.R.1
  • 36
    • 0021223440 scopus 로고
    • Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isozymes, NADPH P450-reductase, glutathione transferases and microsomal cpoxide hydrolase
    • Wolf, C. R., E. Moll, T. Friedberg, F. Oesch, A. Buchmann, W. D. Kuhlmann, H. W. Kunz: Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isozymes, NADPH P450-reductase, glutathione transferases and microsomal cpoxide hydrolase. Carcinogenesis 5, 993-1001 (1984).
    • (1984) Carcinogenesis , vol.5 , pp. 993-1001
    • Wolf, C.R.1    Moll, E.2    Friedberg, T.3    Oesch, F.4    Buchmann, A.5    Kuhlmann, W.D.6    Kunz, H.W.7
  • 37
    • 0019506009 scopus 로고
    • A sensitive method for determination of biphenyl hydroxylase activities using high-performance liquid chromatography
    • Yamazoe, Y., T. Kamataki, R. Kato: A sensitive method for determination of biphenyl hydroxylase activities using high-performance liquid chromatography. Anal. Chem. 111, 126-130 (1981).
    • (1981) Anal. Chem. , vol.111 , pp. 126-130
    • Yamazoe, Y.1    Kamataki, T.2    Kato, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.