Peri- and postnatal changes in reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase content in hepatocytes of rats

Histochemical Journal

Volumn 28, Issue 7, 1996, Pages 505-510

  Watanabe, Jun ^a   Asaka, Youko ^a   Kanamura, Shinsuke ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 REDUCTASE;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; FETUS; LIVER CELL; MALE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT;

EID: 0029790989     PISSN: 00182214     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02331410     Document Type: Article

References (28)

1. FRENCH, J. S., GUENGERICH, F. P. & COON, M. J. (1980) Interaction of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system. J. Biol. Chem. 255, 4112-19.
2. GUSTAFSSON, J-A., MODE, A., NORSTEDT, G. & SKETT, P. (1983) Sex steroid induced changes in hepatic enzymes. Ann. Rev. Physiol. 45, 51-60.
3. HERZFELD, A., FEDERMAN, M. & GREENGARD, O. (1973) Subcellular morphometric and biochemical analysis of developing rat hepatocytes. J. Cell. Biol. 57, 475-83.
4. JACOBSON, M. & KUNTZMAN, R. (1969) Testosterone hydroxylation and pentobarbital oxidation by rat liver microsomes; selective effects of age, sex, castration and testosterone propionate treatment. Steroids 13, 327-41.
5. KANAI, K., WATANABE, J. & KANAMURA, S. (1990) Microphotometric analysis of cytochrome P-450 in periportal, midzonal and perivenular hepatocytes of mice treated with phenobarbital. J. Histochem. Cytochem. 38, 1599-1605.
6. KANAI, K., WATANABE, J., ASAKA, Y., FUJIMOTO, S. & KANAMURA, S. (1992) Postnatal changes in sublobular distribution of NADPH-cytochrome P-450 reductase in rat liver. Histochem. J. 24, 957-63.
7. LAMERS, W. H., HILBERTS, A., FURT, E., SMITH, J., JONGES, G. N., VAN NOORDEN, C. J. F., GAASBEEK-JANZEN, J. W., CHARLES, R. & MOORMAN, A. F. M. (1989) Hepatic enzymic zonation: a reevaluation of the concept of the liver acinus. Hepatology 10, 72-6.
8. MAEDA, K., KAMATAKI, T., NAGAI, T. & KATO, R. (1984) Postnatal development of constitutive forms of cytochrome P-450 in liver microsomes of male and female rats. Biochem. Pharmacol. 33, 509-12.
9. MASAKI, K., YAMAMOTO, A. & TASHIRO, Y. (1987) Cytochrome P-450 and NADPH- cytochrome P-450 reductase are degraded in the autolysosomes in rat liver. J. Cell. Biol. 104, 1207-15.
10. MASTERS, B. S. S., PROUGH, R. A. & KAMIN, H. (1975): Properties of the stable aerobic and anaerobic half reduced states of NADPH-cytochrome c reductase. Biochemistry 14, 607-13.
11. MIWA, G. T., WEST, S. B. & LU, A. Y. H. (1978) Studies on the rate-limiting enzyme component in the microsomal monooxygenase system. J. Biol. Chem. 253, 1921-9.
12. MURRAY, G. I., BARNES, T. S., SEWELL, H. F., EWEN, S. W. B., MELVIN, W. T., SHAW, P. M., FOWLER, J. & BURKE, M. D. (1987) Cytochrome P-450 localization in normal human adult and foetal liver by immunocytochemistry using a monoclonal antibody against human cytochrome P-450. Histochem. J. 19, 537-45.
13. OMIECINSKI, C. J., HASSETT, C. & COSTA, P. (1990) Developmental expression and in situ localization of the phenobarbital-inducible rat hepatic mRNAs for cytochromes CYP2B1, CYP2B2, CYP2C6, and CYP3A1. Mol. Pharmacol. 38, 462-70.
14. POOL, C. F., MADLENER, S., DIEGENBACH, P. C., SLUTTER, A. A. & VAN DERSLUIS, P. (1984) Quantitation of antiserum reactivity in immunocytochemistry. Two new methods for measuring peroxidase activity on antigen-coupled beads incubated according to an immunoperoxidase method. J. Histochem. Cytochem. 32, 921-8.
15. RAM, P. A. & WAXMAN, D. J. (1992) Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms. J. Biol. Chem. 267, 3294-301.
16. RATANASAVANH, D., BEAUNE, P., MOREL, F., FLINOIS, J.-P., GUENGERICH, F. P. & GUILLOUZO, A. (1991) Intralobular distribution and quantitation of cytochrome P-450 enzymes in human liver as a function of age. Hepatology 13, 1142-51.
17. SHAPIRO, B. H., PAMPORI, N. A., LAPENSON, D. P. & WAXMAN, D. J. (1994) Growth hormone-dependent and -independent sexually dimorphic regulation of phenobarbital-induced hepatic cytochromes P-450 2B1 and 2B2. Arch. Biochem. Biophys. 312, 234-9.
18. SMITH, M.T., REDICK, J. A. & BARON, J. (1983) Quantitative immunohistochemistry: a comparison of microdensitometric analysis of unlabeled antibody peroxidase-antiperoxidase staining and of microfluorometric analysis of indirect fluorescent antibody staining for nicotinamide adenosine dinucleotide phosphate (NADPH)-cytochrome c (P-450) reductase in rat liver. J. Histochem. Cytochem. 31, 1183-9.
19. TAIRA, Y., REDICK, J. A. & BARON, J. (1980) An immunohistochemical study on the localization and distribution of NADPH-cytochrome c (P-450) reductase in rat liver. Mol. Pharmacol. 17, 374-81.
20. WATANABE, J. & KANAMURA, S. (1991) An improved microphotometry system for measurement of cytochrome P-450 in hepatocyte cytoplasm. J. Histochem. Cytochem. 39, 689-94.
21. WATANABE, J., KANAI, K. & KANAMURA, S. (1991) Measurement of NADPH- ferrihemoprotein reductase content in sections of liver. J. Histochem. Cytochem. 39, 1635-43.
22. WATANABE, J., ASAKA, Y., KANAI, K. & KANAMURA, S. (1992) Relation between cytochrome P-450 increase and endoplasmic reticulum proliferation in hepatocytes of mice treated with phenobarbital: a microphotometric and morphometric study. J. Histochem. Cytochem. 40, 353-7.
23. WATANABE, J., ASAKA, Y., FUJIMOTO, S. & KANAMURA, S. (1993a) Densities of NADPH- ferrihemoprotein reductase and cytochrome P-450 molecules in the endoplasmic reticulum membrane of rat hepatocytes. J. Histochem. Cytochem. 41, 43-49.
24. WATANABE, J., ASAKA, Y. & KANAMURA, S. (1993b) Postnatal development and sublobular distribution of cytochrome P-450 in rat liver: a microphotometric study. J. Histochem. Cytochem. 41, 397-400.
25. WATANABE, J., ASAKA, Y., TANAKA, T. & KANAMURA, S. (1994) Measurement of NADPH-cytochrome P-450 reductase content in rat liver sections by quantitative immunohistochemistry with a video image processor. J. Histochem. Cytochem. 42, 1161-7.
26. WAXMAN, D. J., DANNAN, G. A. & GUENGERICH, F. P. (1985) Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 24, 4409-17.
27. WOLF, C. R., MOLL, E., FRIEDBERG, T., OESCH, F., BUCHMANN, A., KUHLMANN, W. D. & KUNZ, H. W. (1984) Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isozymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase. Carcinogenesis 5, 993-1001.
28. YASUKOCHI, Y. & MASTERS, B. S. S. (1976) Some properties of a detergent-solubilized NADPH-cytochrome c (P-450) reductase purified by biospecific affinity chromatography. J. Biol. Chem. 251, 5337-44.