Effects of some 7-arylidene and 7-heteroarylidene morphinan-6-ones on the antinociceptive activity of [D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4] deltorphin II and on multiple opioid receptors

Peptides

Volumn 18, Issue 5, 1997, Pages 695-701

  Bhargava, Hemendra N ^a   Zhao, Guo Min ^a   Bian, Jing Tan ^a   Nan, Yang ^a   Upadhyaya, Subash P ^a   Xu, Wei ^a   Dunn III, William J ^a   Bauer, Ludwig ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

7 Arylidene morphinan 6 ones; 7 Heteroarylidene morphinan 6 ones; D Ala2, Glu4 deltrophin II; D Pen2, D Pen5 enkephalin; Antinociception; Guinea pig ileum; Mouse vas deferens; Multiple opioid receptors; Partition coefficients; Structure lipophilicity

Indexed keywords

DELTAKEPHALIN; DELTORPHIN; MORPHINAN DERIVATIVE; NALTREXONE; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; CROSS TOLERANCE; DRUG EFFECT; DRUG RECEPTOR BINDING; LIPOPHILICITY; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; STRUCTURE ANALYSIS; VAS DEFERENS;

ANALGESICS; ANIMALS; BRAIN CHEMISTRY; CELL MEMBRANE; ENKEPHALIN, D-PENICILLAMINE (2,5)-; ENKEPHALINS; GUINEA PIGS; ILEUM; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MORPHINE DERIVATIVES; NALTREXONE; OLIGOPEPTIDES; RECEPTORS, OPIOID; TISSUE DISTRIBUTION; VAS DEFERENS;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0030759449     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(97)00121-6     Document Type: Article

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