Nitric oxide synthase inhibition attenuates tolerance to morphine but not to [D-Ala2,Glu4] deltorphin II, a δ2-opioid receptor agonist in mice

Peptides

Volumn 17, Issue 4, 1996, Pages 619-623

  Zhao, Guo Min ^a   Bhargava, Hemendra N ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Analgesia; L NMMA; L NNA; Morphine; Nitric oxide synthase; Tolerance; D Ala2,Glu4 deltorphin II; 2 Opioid receptor

Indexed keywords

DELTA OPIATE RECEPTOR; DELTORPHIN; MORPHINE; N(G) METHYLARGININE; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE; OPIATE AGONIST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG TOLERANCE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA;

EID: 0029950072     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/0196-9781(96)00073-3     Document Type: Article

References (20)

1. 1. Angulo, A.; Watanabe, Y.; Cadet, J.; Ledoux, M.; McEwen, B. S. Up-regulation of forebrain proenkephalin mRNA subsequent to NMDA receptor blockade. Eur. J. Pharmacol. 244:317-318; 1993.
2. 2. Barjavel, M. J.; Bhargava, H. N. Effect of morphine tolerance and abstinence on nitric oxide synthase activity in brain regions and spinal cord of the mouse. Soc. Neurosci. Abstr. 20:234; 1994.
3. 3. Barjavel, M. J.; Bhargava, H. N. Effect of multiple opioid receptor agonists on the nitric oxide synthase activity in the cerebral cortex. Neurosci. Lett. 181:27-30; 1994.
4. 4. Bhargava, H. N. Diversity of agents that modify opioid tolerance, physical dependence, abstinence syndrome and self-administrative behavior. Pharmacol. Rev. 46:293-324; 1994.
5. 5. Bhargava, H. N. Nitric oxide synthase inhibition blocks tolerance to the analgesic action of U-50.488H, a κ-opioid receptor agonist in the rat. Pharmacology 48:234-241; 1994.
6. 6. Bhargava, H. N. Attenuation of tolerance to, and physical dependence on, morphine in the rat by inhibition of nitric oxide synthase. Gen. Pharmacol. 26:1049-1053; 1995.
7. 2-opioid receptor agonist in mice. Brain Res. (in press).
8. 8. Bredt, D. S.; Hwang, P. M.; Snyder, S. H. Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 347:768-770; 1990.
9. 9. Bredt, D. S.; Snyder, S. H. Nitric oxide, a novel neuronal messenger. Neuron 8:3-11; 1992.
10. 10. Garthwaite, J. Glutamic acid, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14:60-67; 1991.
11. 11. Gudehithlu, K. P.; Bhargava, H. N. Effects of competitive and non-competitive antagonism of NMDA receptor on preproenkephalin mRNA. Soc. Neurosci. Abstr. 21:A724; 1995.
12. 12. Haley, T. J.; McCormick, W. G. Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse. Br. J. Pharmacol. Chemother. 12:12-15; 1957.
13. 13. Knowles, R.; Palacios, M.; Palmer, R. M. J.; Moncada, S. Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of the soluble guanylyl cyclase. Proc. Natl. Acad. Sci. USA 86:5159-5162; 1989.
14. 14. Kolesnikov, Y. A.; Pick, C. G.; Ciszewska, G.; Pasternak, G. W. Blockade of tolerance to morphine but not to κ-opioids by nitric oxide synthase inhibitor. Proc. Natl. Acad. Sci. USA 90:5162-5166; 1993.
15. G-nitro-L-arginine prevents morphine tolerance. Eur. J. Pharmacol. 221:399-400; 1992.
16. 2] deltorphin II in mice: Evidence for delta receptor subtypes. J. Pharmacol. Exp. Ther. 258:583-587; 1991.
17. 17. Moncada, S.; Palmer, R. M. J.; Higgs, E. A. Nitric oxide: Physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43:109-142; 1991.
18. 18. Schmidt, H. H. H. W.; Wilke, P.; Evers B.; Bohme, E. Enzymatic formation of nitric oxide from L-arginine in bovine brain cytosol. Biochem. Biophys. Res. Commun. 165:284-291; 1989.
19. 19. Thorat, S. N.; Reddy, P. L.; Bhargava, H. N. Evidence for the role of nitric oxide in kappa opiate tolerance in mice. Brain Res. 621:171-174; 1993.
20. 1-opioid receptor agonist. Peptides 17:233-236; 1996.