Characterization of stereoselectivity and genetic polymorphism of the debrisoquine hydroxylation in man via analysis of urinary debrisoquine and 4-hydroxydebrisoquine by capillary electrophoresis

Electrophoresis

Volumn 18, Issue 10, 1997, Pages 1875-1881

  Lanz, Matthias ^a   Theurillat, Regula ^a   Thormann, Wolfgang ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Capillary electrophoresis; Cyclodextrin; Debrisoquine; Polymorphism; Stereoselective metabolism

Indexed keywords

ASSAYS; FUSED SILICA; GAS CHROMATOGRAPHY; ORGANIC CHEMICALS; STEREOSELECTIVITY;

CAPILLARY-ZONE ELECTROPHORESIS; CHIRAL SELECTOR; DEBRISOQUINE; DISPOSABLE CARTRIDGE; FUSED-SILICA CAPILLARIES; GENETIC POLYMORPHISMS; PHOSPHATE BUFFERS; STEREO-SELECTIVE; STEREOSELECTIVE METABOLISM; Β-CD;

CAPILLARY ELECTROPHORESIS;

4 HYDROXYDEBRISOQUINE; DEBRISOQUINE; DRUG METABOLITE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; DRUG METABOLISM; ENANTIOMER; GENETIC POLYMORPHISM; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; HYDROXYLATION; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHENOTYPE; STEREOCHEMISTRY; TECHNIQUE; URINALYSIS;

EID: 0030758495     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.1150181025     Document Type: Article

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