Synthesis and antimalarial effects of phenothiazine inhibitors of a plasmodium falciparum cysteine protease

Journal of Medicinal Chemistry

Volumn 40, Issue 17, 1997, Pages 2726-2732

  Domínguez, José N ^a   López, Simón ^a   Charris, Jaime ^a   Iarruso, Lúcido ^a   Lobo, Gricela ^a   Semenov, Andrey ^b   Olson, Jed E ^b   Rosenthal, Philip J ^b,c  

^a UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLORO 1,2 DIHYDRO 2,2 DIMETHYL 4(3H,10H)PHENOTHIAZINONE 5,5 DIOXIDE; 7 FLUORO 1,2 DIHYDRO 2,2 DIMETHYL 4(3H,10H)PHENOTHIAZINONE 5,5 DIOXIDE; ANTIMALARIAL AGENT; PHENOTHIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; PHENOTHIAZINES; PLASMODIUM FALCIPARUM;

EID: 0030758238     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970266p     Document Type: Article

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