PfEMP1, polymorphism and pathogenesis

Annals of Tropical Medicine and Parasitology

Volumn 91, Issue 5, 1997, Pages 551-557

  Newbold, C I ^a   Craig, A G ^a   Kyes, S ^a   Berendt, A R ^a   Snow, R W ^b   Peshu, N ^b   Marsh, K ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; CHONDROITIN 4 SULFATE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; THROMBOSPONDIN; VASCULAR CELL ADHESION MOLECULE 1;

CONFERENCE PAPER; ENDOTHELIUM CELL; ERYTHROCYTE; GENETIC POLYMORPHISM; HOST PARASITE INTERACTION; NONHUMAN; PARASITE VIRULENCE; PATHOGENESIS; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 0030755076     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1080/00034983.1997.11813173     Document Type: Conference Paper

References (37)

1. BARNWELL, J. W., ASCH, A. S., NACHMAN, R. L., YAMAYA, M., AIKAWA, M. & INGRAVALLO, P. (1989). A human 88-kD membrane glycoprotein (CD36) functions in vitro as a receptor for a cytoadherence ligand on Plasmodium falciparum-infected erythrocytes. Journal of Clinical Investigation, 84, 765-772.
2. BARUCH, D. I., PASLOSKE, B. L., SINGH, H. B., BI, X., MA, X. C., FELDMAN, M., TARASCHI, T. F. & HOWARD, R. J. (1995). Cloning the Plasinodium falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitised human erythrocytes. Cell, 82, 77-87.
3. BERENDT, A. R., SIMMONS, D. L., TANSEY, J., NEWBOLD, C. I. & MARSH, K. (1989). Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum. Nature, 341, 57-59.
4. BERENDT, A. R., MCDOWALL, A., CRAIG, A. G., BATES, P. A., STERNBERG, M. J., MARSH, K., NEWBOLD, C. I. & HOGG, N. (1992). The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site. Cell, 68, 71-81.
5. BERENDT, A. R., FERGUSON, D. J., GARDNER, J., TURNER, G., ROWE, A., MCCORMICK, C., ROBERTS, D., CRAIG, A., PINCHES, R., ELFORD, B. C. & NEWBOLD, C. I. (1994). Molecular mechanisms of sequestration in malaria. Parasitology, 108 (Suppl.), S19-S28.
6. BIGGS, B. A., GOOZE, L., WYCHERLEY, K., WILKINSON, D., BOYD, A. W., FORSYTH, K. P., EDELMAN, L., BROWN, G. V. & LEECH, J. H. (1990). Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36. Journal of Experimental Medicine, 171, 1883-1892.
7. BIGGS, B. A., GOOZE, L., WYCHERLEY, K., WOLLISH, W., SOUTHWELL, B., LEECH, J. H. & BROWN, G. V. (1991). Antigenic variation in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America, 88, 9171-9174.
8. BROWN, K. N. & BROWK, I. N. (1965). Immunity to malaria: antigenic variation in chronic infections of Plasmodium knowlesi. Nature, 208, 1286-1288.
9. CARLSON, J., HELMBY, H., HILL, A. V., BREWSTER, D., GREENWOOD, B. M. & WAHLGREN, M. (1990). Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies. Lancet, ii, 1457-1460.
10. CHITNIS, C. E. & MILLER, L. H. (1994). Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion. Journal of Experimental Medicine, 180, 497-506.
11. COOKE, B. M., BERENDT, A. R., CRAIG, A. G., MACGREGOR, J., NEWBOLD, C. I. & NASH, G. B. (1994). Rolling and stationary cytoadhesion of red blood cells parasitized by Plasmodium falciparum: separate roles for ICAM-1, CD36 and thrombospondin. British Journal of Haematology, 87, 162-170.
12. FRIED, M. & DUFFY, P. E. (1996). Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science, 272, 1502-1504.
13. GARDNER, J. P., PINCHES, R. A., ROBERTS, D. J. & NEWBOLD, C. I. (1996). Variant antigens and endothelial adhesion in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America, 93, 3503-3508.
14. GUPTA, S., HILL, A. V., KWIATKOWSKI, D., GREENWOOD, A. M., GREENWOOD, B. M. & DAY, K. P. (1994). Parasite virulence and disease patterns in Plasmodium falciparum malaria. Proceedings of the National Academy of Sciences of the United States of America, 91, 3715-3719.
15. HASLER, T., HANDUNNETTI, S. M., AGUIAR, J. C., VAN SCHRAVENDIJK, M. R., GREENWOOD, B. M., LALLINGER, G., CEGIELSKI, P. & HOWARD, R. J. (1990). In vitro rosetting, cytoadherence, and microagglutination properties of Plasmodium falciparum-infected erythrocytes from Gambian and Tanzanian patients. Blood, 76, 1845-1852.
16. HELMBY, H., CAVELIER, L., PETTERSSON, U. & WAHLGREN, M. (1993). Rosetting Plasmodium falciparum-infected erythrocytes express unique strain-specific antigens on their surface. Infection and Immunity, 61, 284-288.
17. HO, M., SINGH, B., LOOAREESUWAN, S., DAVIS, T. M., BUNNAG, D. & WHITE, N. J. (1991). Clinical correlates of in vitro Plasmodium falciparum cytoadherence. Infection and Immunity, 59, 873-878.
18. HOMMEL, M., DAVID, P. H. & OLIGINO, L. D. (1983). Surface alterations of erythrocytes in Plasmodium falciparum malaria. Antigenic variation, antigenic diversity, and the role of the spleen. Journal of Experimental Medicine, 157, 1137-1148.
19. LEECH, J. H., BARNWELL, J. W., MILLER, L. H. & HOWARD, R. J. (1984). Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes. Journal of Experimental Medicine, 159, 1567-1575.
20. MACPHERSON, G. G., WARRELL, M. J., WHITE, N. J., LOOAREESUWAN, S. & WARRELL, D. A. (1985). Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration. American Journal of Pathology, 119, 385-401.
21. MAGOWAN, C., WOLLISH, W., ANDERSON, L. & LEECH, J. (1988). Cytoadherence by Plasmodium falciparum-infected erythrocytes is correlated with the expression of a family of variable proteins on infected erythrocytes. Journal of Experimental Medicine, 168, 1307-1320.
22. MARSH, K., MARSH, V. M., BROWN, J., WHITTLE, H. C. & GREENWOOD, B. M. (1988). Plasmodium falciparum: the behavior of clinical isolates in an in vitro model of infected red blood cell sequestration. Experimental Parasitology, 65, 202-208.
23. MARSH, K., OTOO, L., HAYES, R. J., CARSON, D. C. & GREENWOOD, B. M. (1989). Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection. Transactions of the Royal Society of Tropical Medicine and Hygiene, 83, 293-303.
24. MARSH, K., FORSTER, D., WARUIRU, C., MWANGI, I., WINSTANLEY, M., MARSH, V., NEWTON, C., WINSTANLEY, P., WARN, P., PESHU, N., PASVOL, G. & SNOW, R. (1995). Indicators of life-threatening malaria in African children. New England Journal of Medicine, 332, 1399-1404.
25. NEWHOLD, C. I., WARN, P., BLACK, G., BERENDT, A. R., CRAIG, A. G., SNOW, R. W., MSOBO, M., PESHU, N. & MARSH, K. (1997). Receptor specific adhesion and clinical disease in Plasmodium falciparum. American Journal of Tropical Medicine and Hygiene, in press.
26. OCKENHOUSE, C. F., KLOTZ, F. W., TANDON, N. N. & JAMIESON, G. A. (1991). Sequestrin, a CD36 recognition protein on Plasmodium falciparum malaria-infected erythrocytes identified by anti-idiotype antibodies. Proceedings of the National Academy of Sciences of the Untied States of America, 88, 3175-3179.
27. OCKENHOUSE, C. F., TEGOSHI, T., MAENO, Y., BENJAMIN, C., HO, M., KAN, K. E., THWAY, Y., WIN, K., AIKAWA, M. & LOBB, R. R. (1992). Human vascular endothelial cell adhesion receptors for Plasmodium falciparum-infected erythrocytes: roles for endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1. Journal of Experimental Medicine, 176, 1183-1189.
28. ROBERTS, D. D., SHERWOOD, J. A., SPITALNIK, S. L., PANTON, L. J., HOWARD, R. J., DIXIT, V. M., FRAZIER, W. A., MILLER, L. H. & GINSBURG, V. (1985). Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence. Nature, 318, 64-66.
29. ROBERTS, D. J., CRAIG, A. G., BERENDT, A. R., PINCHES, R., NASH, G., MARSH, K. & NEWBOLD, C. I. (1992). Rapid switching to multiple antigenic and adhesive phenotypes in malaria. Nature, 357, 689-692.
30. ROGERSON, S. J., CHAIYAROJ, S. C., NG, K., REEDER, J. C. & BROWN, G. V. (1995). Chondroitin sulphate A is a cell surface receptor for Plasmodium falciparum infected erythrocytes. Journal of Experimental Medicine, 182, 15-20.
31. ROWE, A., OBEIRO, J., NEWBOLD, C. I. & MARSH, K. (1995). Plasmodium falciparum resetting is associated with malaria severity in Kenya. Infection and Immunity, 63, 2323-2326.
32. SHERMAN, I. W., CRANDALL, I. & SMITH, H. (1992). Membrane proteins involved in the adherence of Plasmodium falciparum-infected erythrocytes to the endothelium. Biology of the Cell, 74, 161-178.
33. SIM, B. K., CHITNIS, C. E., WASNIOWSKA, K., HADLEY, T. J. & MILLER, L. H. (1994). Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum. Science, 264, 1941-1944.
34. SMITH, J. D., CHITNIS, C. E., CRAIG, A. G., ROBERTS, D. J., HUDSON-TAYLOR, D. E., PETERSON, D. S., PINCHES, R. A., NEWBOLD, C. I. & MILLER, L. H. (1995). Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherence phenotypes of infected erythrocytes. Cell, 82, 101-100.
35. SU, X.-Z., HEATWOLE, V., WERTHEIMER, S., GUINET, F., HERRFELDT, J. A., PETERSON, D. S., RAVETCH, J. A. & WELLEMS, T. E. (1995). The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum infected erythrocytes. Cell, 82, 89-100.
36. TURNER, G. D. H., MORRISON, H., JONES, M., DAVIS, T. M., LOOAREESUWAN, S., BULEY, I. D., GATTER, K. C., NEWBOLD, C. I., PUKRITAYAKAMEE, S., NAGACHINTA, B., WHITE, N. J. & BERENDT, A. R. (1994). An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. American Journal of Pathology, 145, 1057-1069.
37. UDOMSANGPETCH, R., AIKAWA, M., BERZINS, K., WAHLGREN, M. & PERLMANN, P. (1989). Cytoadherence of knobless Plasmodium falciparum-infected erythrocytes and its inhibition by a human monoclonal antibody. Nature, 338, 763-765.