Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase

Journal of Biological Chemistry

Volumn 272, Issue 41, 1997, Pages 25596-25601

  Watkins, Linette M ^a   Mahoney, Heather J ^a   McCulloch, Jennifer K ^a   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEPHATE; CHOLINESTERASE INHIBITOR; DYFLOS; HISTIDINE; MUTANT PROTEIN; ORGANOPHOSPHATE INSECTICIDE; PARAOXON; PHENYLALANINE; PHOSPHATASE; TRYPTOPHAN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BREVUNDIMONAS DIMINUTA; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MODIFICATION; ENZYME SUBSTRATE; HYDROLYSIS; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ARYLDIALKYLPHOSPHATASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESTERASES; GENETIC ENGINEERING; HYDROLYSIS; ISOFLUROPHATE; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; ORGANOTHIOPHOSPHORUS COMPOUNDS; PARAOXON; PSEUDOMONAS; ZINC;

EID: 0030754819     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.41.25596     Document Type: Article

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