Late gene expression from the Epstein-Barr virus BclF1 and BFRF3 promoters does not require DNA replication in cis

Journal of Virology

Volumn 71, Issue 11, 1997, Pages 8726-8734

  Serio, Tricia R ^a   Kolman, John L ^a,c   Miller, George ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; DNA POLYMERASE;

ARTICLE; DNA REPLICATION; EPSTEIN BARR VIRUS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SOUTHERN BLOTTING; VIRUS GENOME; VIRUS LATENCY; VIRUS REPLICATION;

EID: 0030754333     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.11.8726-8734.1997     Document Type: Article

References (33)

1. Baer, R., A. T. Bankier, M. D. Biggin, P. L. Deininger, P. J. Farrell, T. J. Gibson, G. Hatfull, G. S. Hudson, S. C. Satchwell, C. Seguin, P. S. Tuffnell, and B. G. Barrell. 1984. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310:207-211.
2. Cayrol, C., and E. K. Flemington. 1996. The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitors. EMBO J. 15:2748-2759.
3. Countryman, J., and G. Miller. 1985. Activation of expression of latent Epstein-Barr virus after gene transfer with a small cloned subfragment of heterogeneous viral DNA. Proc. Natl. Acad. Sci. USA 82:4085-4089.
4. Countryman, J., H. Jenson, R. Seibl, H. Wolf, and G. Miller. 1987. Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency. J. Virol. 61:3672-3679.
5. Countryman, J. K., H. Jenson, E. Grogan, and G. Miller. 1985. A 2.7kb rearranged DNA fragment from Epstein-Barr virus capable of disruption of latency. Cancer Cells 4:517-523.
6. Datta, A. K., and R. E. Hood. 1981. Mechanism of inhibition of Epstein-Barr virus replication by phosphonoformic acid. Virology 114:52-59.
7. Decaussin, G., V. Leclerc, and T. Ooka. 1995. The lytic cycle of Epstein-Barr virus in the nonproducer Raji line can be rescued by the expression of a 135-kilodalton protein encoded by the BALF2 open reading frame. J. Virol. 69:7309-7314.
8. Fixman, E. D., G. S. Hayward, and S. D. Hayward. 1995. Replication of Epstein-Barr virus oriLyt: lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays. J. Virol. 69:2998-3006.
9. Fixman, E. D., G. S. Hayward, and S. D. Hayward. 1992. trans-acting requirements for replication of Epstein-Barr virus ori-Lyt. J. Virol. 66:5030-5039.
10. Francis, A. L., L. Gradoville, and G. Miller. 1997. Alteration of a single serine in the basic domain of the Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency. J. Virol. 71:3054-3061.
11. Fronko, G. E., W. K. Long, B. Wu, T. Papadopoulos, and E. E. Henderson. 1989. Relationship between methylation status and expression of an Epstein-Barr virus (EBV) capsid antigen gene. Biochem. Biophys. Res. Commun. 159:263-270.
12. Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
13. Hammerschmidt, W., and B. Sugden. 1988. Identification and characterization of orilyt, a lytic origin of DNA replication of Epstein-Barr virus. Cell 55:427-433.
14. Johnson, P. A., and R. D. Everett. 1986. The control of herpes simplex virus type-1 late gene transcription: a 'TATA box'/cap site region is sufficient for fully efficient regulated activity. Nucleic Acids Res. 14:8247-8264.
15. Katz, B. Z., N. Raab-Traub, and G. Miller. 1989. Latent and replicating forms of Epstein-Barr virus DNA in lymphomas and lymphoproliferative diseases. J. Infect. Dis. 160:589-598.
16. Kenney, S., J. Kamine, E. Holley-Guthrie, J.-C. Lin, E.-C. Mar, and J. Pagano. 1989. The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters. J. Virol. 63:1729-1736.
17. Kieff, E. 1996. Epstein-Barr virus and its replication, p. 2343-2396. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields' virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
18. Kolman, J. 1992. Ph.D. thesis. Yale University, New Haven, Conn.
19. Kolman, J. L., N. Taylor, L. Gradoville, J. Countryman, and G. Miller. 1996. Comparing transcriptional activation and autostimulation by ZEBRA and ZEBRA/c-Fos chimeras. J. Virol. 70:1493-1504.
20. Lin, J.-C., N. D. Sista, F. Besençon, J. Kamine, and J. S. Pagano. 1991. Identification and functional characterization of Epstein-Barr virus DNA polymerase by in vitro transcription-translation of a cloned gene. J. Virol. 65:2728-2731.
21. Menezes, J., W. Leifbold, G. Klein, and G. Clements. 1975. Establishment and characterization of an Epstein-Barr virus (EBV)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome negative African Burkitt's lymphoma. Biomedicine 22:276-284.
22. Pearson, G. R., B. Vroman, B. Chase, T. Sculley, M. Hummel, and E. Kieff. 1983. Identification of polypeptide components of the Epstein-Barr virus early antigen complex with monoclonal antibodies. J. Virol. 47:193-201.
23. Pulvertaft, R. J. V. 1964. Cytology of Burkitt's tumour (African lymphoma). Lancet i:238-240.
24. Rabbin, M., L. Heston, and G. Miller. 1983. Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells. Proc. Natl. Acad. Sci. USA 80:2762-2766.
25. Rickinson, A. B., S. Finerty, and M. A. Epstein. 1978. Inhibition by phosphonoacetate of the in vitro outgrowth of Epstein-Barr virus genome-containing cell lines from the blood of infectious mononucleosis patients. IARC Sci. Publ. 1978:721-728.
26. Roizman, B., and A. E. Sears. 1996. Herpes simplex viruses and their replication, p. 2231-2295. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields' virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
27. Serio, T. R., A. Angeloni, J. L. Kolman, L. Gradoville, R. Sun, D. A. Katz, W. Van Grunsven, J. Middeldorp, and G. Miller. 1996. Two 21-kilodalton components of the Epstein-Barr virus capsid antigen complex and their relationship to ZEBRA-associated protein p21 (ZAP21). J. Virol. 70:8047-8054.
28. Serio, T. R. Unpublished data.
29. Summers, W. C., and G. Klein. 1976. Inhibition of Epstein-Barr virus DNA synthesis and late gene expression by phosphonoacetic acid. J. Virol. 18:151-155.
30. Szyf, M., L. Eliasson, V. Mann, G. Klein, and A. Razin. 1985. Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle. Proc. Natl. Acad. Sci. USA 82:8090-8094.
31. Taylor, N., J. Countryman, C. Rooney, D. Katz, and G. Miller. 1989. Expression of the BZLF1 latency-disrupting gene differs in standard and defective Epstein-Barr viruses. J. Virol. 63:1721-1728.
32. Yates, J. L., and N. Guan. 1991. Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cells. J. Virol. 65:483-488.
33. Yates, J. L., N. Warren, and B. Sugden. 1985. Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells. Nature 313: 812-815.