Estrogen therapy enhances calcium absorption and retention and diminishes bone turnover in young girls with Turner's syndrome: A calcium kinetic study

Metabolism: Clinical and Experimental

Volumn 46, Issue 8, 1997, Pages 908-913

  Mauras, Nelly ^a   Vieira, Nancy E ^b   Yergey, Alfred L ^b  

^a NEMOURS CHILDREN S CLINIC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; TESTOSTERONE;

ARTICLE; CALCIUM ABSORPTION; CALCIUM INTAKE; CALCIUM METABOLISM; CHILD; CLINICAL ARTICLE; ESTROGEN THERAPY; FEMALE; HUMAN; KINETICS; OSTEOLYSIS; PRIORITY JOURNAL; TURNER SYNDROME; VITAMIN INTAKE;

EID: 0030754065     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(97)90078-0     Document Type: Article

References (37)

1. Turner RT, Riggs BL, Speslberg TC: Skeletal effects of estrogen. Endocr Rev 15:275-300, 1994
2. Partiff AM: Quantum concept of bone remodeling and turnover: Implications for the pathogenesis of osteoporosis. Calcif Tissue Int 28:1-5, 1979
3. Kiel DP, Felson DT, Anderson JJ, et al: Hip fracture and the use of estrogens in post-menopausal women. N Engl J Med 317:1169-1174, 1987
4. Ettinger B, Genant HK, Cann CE: Post-menopausal bone loss is prevented by treatment with low-dosage estrogen with calcium. Ann Intern Med 106:40-45, 1987
5. Johansen SJ, Riis BJ, Hassager C, et al: The effect of a GnRH(a) (nafarelin) on bone metabolism. J Clin Endocrinol Metab 67:701-706, 1988
6. Klibanski A, Biller BMK, Rosenthal DI, et al: Effects of prolactin and estrogen deficiency in amenorrheic bone loss. J Clin Endocrinol Metab 67:124-130, 1988
7. Sylven L, Hagenfeldt K, Ringertz H: Bone mineral density in middle aged women with Turner's syndrome. Eur J Endocrinol 132:47-52, 1995
8. Kurabayashi T, Yasuda M, Fujimarci T, et al: Effect of hormone replacement therapy on spinal bone mineral density and T lymphocyte subsets in premature ovarian failure and Turner's syndrome. Int J Gynecol Obstet 52:25-31, 1993
9. Mora S, Weber G, Guarneri MP, et al: Effect of estrogen replacement therapy on bone mineral content in girls with Turner's syndrome. Obstet Gynecol 79:747-751, 1992
10. Yergey AL, Abrams SA, Vieira NE, et al: Recent studies of human calcium metabolism using stable isotope tracers. Can J Physiol Pharmacol 68:973-976, 1990
11. Abrams SA: Clinical studies of mineral metabolism in children using stable isotopes. J Pediatr Gastroenterol Nutr 19:151-163, 1994
12. Mauras N, Haymond MW, Darmaun D, et al: Calcium and protein kinetics in prepubertal boys: Positive effects of testosterone. J Clin Invest 93:1014-1019, 1994
13. Abrams SA, Stuff JE: Calcium metabolism in girls: Current dietary intakes lead to low rates of calcium absorption and retention during puberty. Am J Clin Nutr 60:739-743, 1994
14. Mauras N, Rogol AD, Haymond MW, et al: Sex steroid, growth hormone, IGF-I: Neuroendocrine and metabolic regulation in puberty. Horm Res 45:74-80, 1995
15. Berman M, Weiss MF: SAAM Manual (Simulation, Analysis and Modeling). Bethesda, MD, DHEW Publication No. (National Institutes of Health)78-180, 1990
16. Abrams SA, Sidbury JB, Muenzer J, et al: Stable isotopic measurement of endogenous fecal calcium excretion in children. J Pediatr Gastroenterol Nutr 12:469-473, 1991
17. Abrams SA, O'Brien KO, Stuff DE: Changes in calcium kinetics associated with menarche. J Clin Endocrinol Metab 81:2017-2020, 1996
18. Mauras N: Estrogens do not affect whole body protein metabolism in the prepubertal female. J Clin Endocrinol Metab 80:2842-2845, 1995
19. 42Ca. Pediatr Res 34:455-459, 1993
20. Gennari C, Agnuscki D, Nardi P, et al: Estrogen preserves a normal intestinal responsiveness to 1,25 dihydroxy vitamin D3 in oophorectomized women. J Clin Endocrinol Metab 71:1288-1295, 1990
21. Heaney RP, Recker RR, Stegman MR, et al: Calcium absorption in women: Relationships to calcium intake, estrogen status, and age. J Bone Miner Res 4:469-475, 1995
22. Miller SC, Slupe JG, Redd EH, et al: Changes in bone mineral and bone formation rates during pregnancy and lactation in rats. Bone 7:283-287, 1986
23. Hartwell D, Riis BJ, Christiansen C: Changes in vitamin D metabolism during natural and medical menopause. J Clin Endocrinol Metab 71:127-132, 1990
24. Saggese G, Federico G, Bertelloni S, et al: Mineral metabolism in Turner's syndrome: Evidence for impaired renal vitamin D metabolism and normal osteoblast function. J Clin Endocrinol Metab 75:998-1001, 1992
25. Smith EP, Boyd J, Frank GR, et al: Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 331:1056-1061, 1994
26. Mauras N, Rogol AD, Veldhuis JD: Specific time-dependent actions of low-dose ethinyl estradiol administration on the episodic release of GH, FSH and LH in prepubertal girls with Turner's syndrome. J Clin Endocrinol Metab 69:1053-1058, 1989
27. Mauras N, Rogol AD, Veldhuis JD: Increased hGH production rate after low-dose estrogen therapy in prepubertal girls with Turner's syndrome. Pediatr Res 28:626-630, 1990
28. Mauras N, Doi SQ, Shapiro JR: Recombinant human insulin-like growth factor I, recombinant human growth hormone, and sex steroids: Effects on markers of bone turnover in humans. J Clin Endocrinol Metab 81:2222-2226, 1996
29. Bunt JC, Going SB, Lohman TG, et al: Variation in bone mineral content and estimated body fat in young adult females. Med Sci Sports Exerc 22:564-569, 1990
30. Buchanan JR, Lloyd T, Myers C, et al: Determinants of peak trabecular bone mass in women: The roles of androgen, estrogen and exercise. J Bone Miner Res 3:673-680, 1988
31. Lloyd T, Rollings N, Andor MB, et al: Determinants of bone density in young women. I. Relationships among pubertal development, total body bone mass, and total body bone density in premenarcheal females. J Clin Endocrinol Metab 75:383-387, 1992
32. Finkelstein JS, Neer RM, Biller BMK, et al: Osteopenia in men with a history of delayed puberty. N Engl J Med 326:600-604, 1992
33. Johnston CC, Miller JZ, Slemenda CW, et al: Calcium supplementation and increases in bone mineral density in children. N Engl J Med 327:82-87, 1992
34. Klein KO, Baron J, Colli MJ, et al: Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay. J Clin Invest 94:2475-2480, 1994
35. Levine-Ross J, Myerson LL, Skerda M: Effect of low doses of estradiol on 6 month growth rates and predicted height in patients with Turner's syndrome. J Pediatr 109:950-953, 1986
36. Rosenfield R: Toward optional estrogen replacement therapy. N Engl J Med 309:1120-1121, 1983
37. Rosenfeld RG, Tesch LG, Rodriguez-Rigali LJ, et al: Recommendations for diagnosis, treatment and management of individuals with Turner's syndrome. Endocrinologist 4:351-358, 1994