Transforming region of 243R E1A contains two overlapping but distinct transactivation domains

DNA and Cell Biology

Volumn 16, Issue 11, 1997, Pages 1321-1333

  Sang, Nianli ^a   Claudio, Pier Paolo ^a   Fu, Yan ^a   Horikoshi, Nobuo ^b,c   Graeven, Ullrich ^b,d   Weinmann, Roberto ^b   Giordano, Antonio ^a,e  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^c PRINCETON UNIVERSITY   (United States)

^d RUHR UNIVERSITY BOCHUM   (Germany)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; ONCOPROTEIN; TATA BINDING PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; GENETIC CONSERVATION; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALIA; RODENTIA;

EID: 0031457384     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1997.16.1321     Document Type: Article

References (16)

1. AVANTAGGIATL, M.L., OGRYZKO, V., GARDNER, K., GIORDANO, A., LEVINE, A.S., and KELLY, K. (1997). Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89, 1175-1184.
2. BAGCHI, S., WEINMANN, R. and RAYCHAUDHURI, P. (1991). The retinoblastoma protein copurifies with E2F-1, an E1A-regulated inhibitor of the transcription factor E2F. Cell 65, 1063-1072.
3. BANNISTER, A.J., and KOUZARIDES, T. (1995). CBP-induced stimulation of c-Fos activity is abrogated by E1A. EMBO J. 14, 4758-4762.
4. BERK, A.J. (1986). Functions of adenovirus E1A. Cancer Surv. 5, 367-387.
5. BONDESSON, M., MANNERVIK, M., AKUSJARVI, G., and SVENSSON, C. (1994). An adenovirus E1A transcriptional repressor domain functions as an activator when tethered to a promoter. Nucleic Acids Res. 22, 3053-3060.
6. BORRELLI, E., HEN, R., and CHAMBON, P. (1984). Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature 312, 608-612.
7. BOYER, T.G., and BERK, A. (1993). Functional interaction of adenovirus E1A with hoIo-TFIID. Genes & Dev. 7, 1810-1823.
8. CARUSO, M., MARTELLI, F., GIORDANO, A., and FELSANI, A. (1993). Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein. Oncogene 8, 267-278.
9. CHELLAPPAN, S.P. (1994). The E2F transcription factor: Role in cell cycle regulation and differentiation. Mol. Cell. Differ. 2, 201-220.
10. CHASMAN, D.I., LEATHERWOOD, J., CAREY, M., PTASHNE, M., and KORNBERG, R.D. (1989). Activation of yeast polymerase II transcription by Herpesvirus VP16 and GAL4 derivatives in vitro. Mol. Cell. Biol. 9, 4746-4749.
11. CLAUDIO, P.P., HOWARD, C.M., BALDI, A., DE LUCA, A., FU, Y., CONDORELLI, G.L., SUN, Y., COLBURN, N., CALABRETTA, B., and GIORDANO, A. (1994). p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. Cancer Res. 5-4, 5556-5560.
12. DATTA, P.K., and BAGCHI, S. (1994). Repression of transforming growth factor beta 1 promoter by the adenovirus oncogene E1A. Identification of a unique GC-rich sequence as a target for E1A repression. J. Biol. Chem. 269, 25392-25399.
13. FEILOTTER, U.E., HANNON, G.J., RUDDEL, C.J., and BEACH, D. (1994). Construction of an improved host strain for two hybrid screening. Nucleic Acids Res. 22, 1502-1503.
14. GE, R., LIU, X., and RICCIARDI, R.P. (1994). E1A oncogene of adenovirus-12 mediates trans-repression of MHC class I transcription in Ad5/Ad12 somatic hybrid transformed cells. Virology 203, 389-392.
15. GEISBERG, J.V., LEE, W.S., BERK, A.J., and RICCIARDI, R.P. (1994). The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein. Proc. Natl. Acad. Sci. USA 91, 2488-2492.
16. GIORDANO, A., WHYTE, P., HARLOW, E., FRANZA, B.R., JR., BEACH, D., and DRAETTA, G. (1989). A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells. Cell 58, 981-990.