Functional groups on the cleavage site pyrimidine nucleotide are required for stabilization of the hammerhead transition state

RNA

Volumn 3, Issue 10, 1997, Pages 1135-1142

  Baidya, Narayan ^a   Ammons, Glenyss E ^a   Matulic Adamic, Jasenka ^b   Karpeisky, Alexander M ^b   Beigelman, Leonid ^b   Uhlenbeck, Olke C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b Sirna Therapeutics Inc   (United States)

Author keywords

Catalytic RNA; Ribozyme; Structure function

Indexed keywords

PYRIMIDINE NUCLEOTIDE; RIBOZYME;

ARTICLE; ENZYME STRUCTURE; EQUILIBRIUM CONSTANT; HYDROGEN BOND; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MODIFICATION; REACTION ANALYSIS; X RAY ANALYSIS;

CYTIDINE; HYDROGEN BONDING; KINETICS; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PYRIMIDINES; RNA, CATALYTIC; STRUCTURE-ACTIVITY RELATIONSHIP;

SPHYRNA;

EID: 0030752599     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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