Net-b, a Ras-insensitive factor that forms ternary complexes with serum response factor on the serum response element of the fos promoter

Molecular and Cellular Biology

Volumn 17, Issue 10, 1997, Pages 5667-5678

  Giovane, Antoine ^a   Sobieszczuk, Peter ^a,b   Ayadi, Abdelkader ^a   Maira, Sauveur Michel ^a   Wasylyk, Bohdan ^a  

^a CNRS   (France)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; LIPOPOLYSACCHARIDE; RNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN 3T3; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; FIBROBLAST; MOUSE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0030751507     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.10.5667     Document Type: Article

References (57)

1. Beitel, G. J., S. Tuck, I. Greenwald, and H. R. Horvitz. 1995. The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes Dev. 9:3149-3162.
2. Bradford, A. P., K. E. Conrad, C. Wasylyk, B. Wasylyk, and A. Gutierrez-Hartmann. 1995. Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain. Mol. Cell. Biol. 15:2849-2857.
3. Brunner, D., K. Ducker, N. Oellers, E. Hafen, H. Scholz, and C. Klambt. 1994. The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway. Nature 370:386-389.
4. Coffer, P., M. de Jonge, A. Mettouchi, B. Binetruy, J. Ghysdael, and W. Kruijer. 1994. junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2. Oncogene 9:911-921.
5. Croissant, J. D., J.-H. Kim, G. Eichele, L. Goering, J. Lough, R. Prywes, and R. J. Schwartz. 1996. Avian serum response factor expression restricted primarily to muscle cell lineages is required for a-actin gene transcription. Dev. Biol. 177:250-264.
6. Downward, J. 1995. KSR: a novel player in the RAS pathway. Cell 83:831-834.
7. Galang, C. K., C. J. Der, and C. A. Hauser. 1994. Oneogcnic Ras can induce transcriptional activation through a variety of promoter elements, including tandem c-Ets-2 binding sites. Oncogene 9:2913-2921.
8. Gille, H., M. Kortenjann, O. Thomae, C. Moomaw, C. Slaughter, M. H. Cobb, and P. E. Shaw. 1995. ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J. 14:951-962.
9. Gille, H. G., A. D. Sharrocks, and P. E. Shaw. 1992. Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at the c-fos promotor. Nature 358:414-417.
10. Giovane, A., A. Pintzas, S. M. Maira, P. Sobieszczuk, and B. Wasylyk. 1994. Net, a new ets transcription factor that is activated by Ras. Genes Dev. 8:1502-1513.
11. Giovane, A., P. Sobieszczuk, C. Mignon, M. G. Mattei, and B. Wasylyk. 1995. Locations of the ets subfamily members net, elk1, and sap1 (ELK3, ELK1, and ELK4) on three homologous regions of the mouse and human genomes. Genomics 29:769-772.
12. 11a. Giovane, A., and B. Wasylyk. Unpublished results.
13. Greenberg, M. E., and E. B. Ziff. 1984. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311:433-438.
14. Grevin, D., S. Ung, F. Denhez, M. Dehem, B. Quatannens, A. Begue, D. Stehelin, and P. Martin. 1996. Structure and organization of the mouse elk1 gene. Gene 174:185-188.
15. Guillemin, K., J. Groppe, K. Ducker, R. Treisman, E. Hafen, M. Affolter, and M. A. Krasnow. 1996. The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122:1353-1362.
16. Gum, R., E. Lengyel, J. Juarez, J. H. Chen, H. Sato, M. Seiki, and D. Boyd. 1996. Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J. Biol. Chem. 271:10672-10680.
17. Han, J., J. D. Lee, L. Bibbs, and R. J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811.
18. Han, J., J. D. Lee, P. S. Tobias, and R. J. Ulevitch. 1993. Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J. Biol. Chem. 268:25009-25014.
19. Herrera, R. E., P. E. Shaw, and A. Nordheim. 1989. Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction. Nature 340:68-70.
20. Hill, C. S., J. Wynne, and R. Treisman. 1994. Serum-regulated transcription by serum response factor (SRF): a novel role for the DNA binding domain. EMBO J. 13:5421-5432.
21. Hill, C. S., J. Wynne, and R. Treisman. 1995. The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81:1159-1170.
22. Hipskind, R. A., M. Baccarini, and A. Nordheim. 1994. Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo. Mol. Cell. Biol. 14:6219-6231.
23. Hipskind, R. A., D. Buscher, A. Nordheim, and M. Baccarini. 1994. Ras/MAP kinase-dependertt and -independent signaling pathways target distinct ternary complex factors. Genes Dev. 8:1803-1816.
24. Hipskind, R. A., V. N. Rao, C. G. Mueller, E. S. Reddy, and A. Nordheim. 1991. Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF. Nature 354:531-534.
25. Janknecht, R., M. A. Cahill, and A. Nordheim. 1995. Signal integration at the c-fos promoter. Carcinogenesis 16:443-450.
26. Janknecht, R., W. H. Ernst, and A. Nordheim. 1995. SAP1a is a nuclear target of signaling cascades involving ERKs. Oncogene 10:1209-1216.
27. Janknecht, R., D. Monte, J. L. Baert, and Y. de Launoit. 1996. The ETS-related transcription factor ERM is a nuclear target of signaling cascades involving MAPK and PKA. Oncogene 13:1745-1754.
28. Janknecht, R., and A. Nordheim. 1992. Elk-1 protein domains required for direct and SRF-assisted DNA-binding. Nucleic Acids Res. 20:3317-3324.
29. Johansen, F.-E., and R. Prywes. 1994. Two pathways tor serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol. Cell. Biol. 14:5920-5928.
30. Kiaris, H., and D. A. Spandidos. 1995. Mutations of ras genes in human tumours. Int. J. Oncol. 7:413-421.
31. Konig, H., H. Ponta, U. Rahmsdorf, M. Buscher, A. Schonthal, H. J. Rahmsdorf, and P. Herrlich. 1989. Autoregulation of fos: the dyad symmetry element as the major target of repression. EMBO J. 8:2559-2566.
32. Lai, Z. C., and G. M. Rubin. 1992. Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein. Cell 70:609-620.
33. Langer, S. J., D. M. Bortner, M. F. Roussel, C. J. Sherr, and M. C. Ostrowski. 1992. Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression. Mol. Cell. Biol. 12:5355-5362.
34. Lopez, M., P. Oettgen, Y. Akbarali, U. Dendorfer, and T. A. Libermann. 1994. ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development. Mol. Cell. Biol. 14:3292-3309.
35. Maira, S.-M., J.-M. Wurtz, and B. Wasylyk. 1996. Net (ERP/SAP2), one of the Ras inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. EMBO J. 15:5849-5865.
36. Marais, R., J. Wynne, and R. Treisman. 1993. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73:381-393.
37. O'Neill, E. M., I. Rebay, R. Tjian, and G. M. Rubin. 1994. The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78:137-147.
38. Pingoud, V., R. Zinck, R. A. Hipskind, R. Janknecht, and A. Nordheim. 1994. Heterogeneity of ternary complex factors in HeLa cell nuclear extracts. J. Biol. Chem. 269:23310-23317.
39. Price, M. A., F. H. Cruzalegui, and R. Treisman. 1996. The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J. 15:6552-6563.
40. Price, M. A., A. E. Rogers, and R. Treisman. 1995. Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET). EMBO J. 14:2589-2601.
41. Rao, V. N., K. Huebner, M. Isobe, A. ar-Rushdi, C. M. Croce, and E. S. Reddy. 1989. elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints. Science 244:66-70.
42. Rivera, V. M., C. K. Miranti, R. P. Misra, D. D. Ginty, R.-H. Chen, J. Blenis, and M. E. Greenberg. 1993. A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol. Cell. Biol. 13:6260-6273.
43. Sadowski. H. B., and M. Z. Gilman. 1993. Cell-free activation of a DNA-binding protein by epidermal growth factor. Nature 362:79-83.
44. Schanke, J. T., A. Marcuzzi, R. P. Podzorski, and B. Van Ness. 1994. An AP1 binding site upstream of the kappa immunoglobulin intron enhancer binds inducible factors and contributes to expression. Nucleic Acids Res. 22:5425-5432.
45. Sgouras, D. N., M. A. Athanasiou, G. J. Beal, R. J. Fisher, D. G. Blair, and G. J. Mavrothalassitis. 1995. ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation. EMBO J. 14:4781-4793.
46. Sharp, P. A. 1994. Split genes and RNA splicing. Cell 77:805-815.
47. Shaw, P. E., S. Frasch, and A. Nordheim. 1989. Repression of c-fos transcription is mediated through p67SRF bound to the SRE. EMBO J. 8:2567-2574.
48. Taylor, M., R. Treisman, N. Garrett, and T. Mohun. 1989. Muscle-specific (CArG) and serum-responsive (SRE) promoter elements are functionally interchangeable in Xenopus embryos and mouse fibroblasts. Development 106:67-78.
49. Tei, H., I. Nihonmatsu, T. Yokokura, R. Ueda, Y. Sano, T. Okuda, K. Sato, K. Hirata, S. C. Fujita, and D. Yamamoto. 1992. pokkuri, a Drosophila gene encoding an E-26-specific (Ets) domain protein, prevents overproduction of the R7 photoreceptor. Proc. Natl. Acad. Sci. USA 89:6856-6860.
50. Thompson, M. J., M. W. Roe, R. K. Malik, and P. J. Blackshear. 1994. Insulin and other growth factors induce binding of the ternary complex and a novel protein complex to the c-tos serum response element. J. Biol. Chem. 269:21127-21135.
51. Treisman, R. 1996. Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8:205-215.
52. Tuil, D., N. Clergue, D. Montarras, C. Pinset, A. Kahn, and F. Phan-Dinh-Tuy. 1990. CC Ar GG boxes, cis-acting elements with a dual specificity. Muscle-specific transcriptional activation and serum responsiveness. J. Mol. Biol. 213:677-686.
53. Wasylyk, B., S. L. Hahn, and A. Giovane. 1993. The Ets family of transcription factors. Eur. J. Biochem. 211:7-18. (Erratum, 215:907, 1993.)
54. Wasylyk, B., and A. Nordheim. 1997. Ets transcription factors: partners in the integration of signal responses, p. 251-284. In A. G. Papavassiliou (ed.), Transcription factors in eucaryotes. R. G. Landes Co., Georgetown, Tex.
55. Wasylyk, C., A. P. Bradford, A. Gutierrez-Hartmann, and B. Wasylyk. 1997. Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2. Oncogene 14:899-913.
56. Wasylyk, C., S. M. Maira, P. Sobieszczuk, and B. Wasylyk. 1994. Reversion of Ras transformed cells by Ets transdominant mutants. Oncogene 9:3665-3673.
57. Zinck, R., R. A. Hipskind, V. Pingoud, and A. Nordheim. 1993. c-fos transcriptional activation and repression correlate temporally with the phosphorylation status of TCF. EMBO J. 12:2377-2387.