메뉴 건너뛰기




Volumn 14, Issue 9, 1997, Pages 1106-1114

Flow cytometry applications in pharmacodynamics and drug delivery

Author keywords

Antibodies; Anticancer agents; Cytokines; Fluorescence activated cell sorting; Fluorophore; Gene therapy; Immunosuppressants; Oligonucleotides

Indexed keywords

ALPHA INTERFERON; ANTHRACYCLINE; ANTIESTROGEN; ANTINEOPLASTIC AGENT; BROXURIDINE; CHLORPROMAZINE; CISPLATIN; CYCLOSPORIN; CYCLOSPORIN A; CYTOCHROME P450; CYTOKINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; ETHIDIUM BROMIDE; GENE PRODUCT; GLUCOCORTICOID; IMMUNOGLOBULIN; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; MIFEPRISTONE; OKT 3; OLIGONUCLEOTIDE; PACLITAXEL; PROPIDIUM IODIDE; TAMOXIFEN; TOREMIFENE; UNINDEXED DRUG; VACCINE; VERAPAMIL;

EID: 0030751367     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012178001348     Document Type: Review
Times cited : (14)

References (62)
  • 2
    • 0028819507 scopus 로고
    • Quantitation of cellular receptors by a new immunocytochemical flow cytometry technique
    • R. J. Zagursky, D. Sharp, K. A. Solomon, and A. Schwartz. Quantitation of cellular receptors by a new immunocytochemical flow cytometry technique. Biotechniques 18:504-9 (1995).
    • (1995) Biotechniques , vol.18 , pp. 504-509
    • Zagursky, R.J.1    Sharp, D.2    Solomon, K.A.3    Schwartz, A.4
  • 3
    • 0029000164 scopus 로고
    • Enhancement of radiation response of prostatic carcinoma by taxol: Therapeutic potential for late-stage malignancy
    • B. L. Lokeshwar, S. M. Ferrell, and N. L. Block. Enhancement of radiation response of prostatic carcinoma by taxol: therapeutic potential for late-stage malignancy. Anticancer Research 15:93-8 (1995).
    • (1995) Anticancer Research , vol.15 , pp. 93-98
    • Lokeshwar, B.L.1    Ferrell, S.M.2    Block, N.L.3
  • 4
    • 0029366548 scopus 로고
    • Flow cytometric analysis of cell cycle for the action mechanism of antineoplastic agents
    • K. Kawamoto. Flow cytometric analysis of cell cycle for the action mechanism of antineoplastic agents. Human Cell 8:85-8 (1995).
    • (1995) Human Cell , vol.8 , pp. 85-88
    • Kawamoto, K.1
  • 6
    • 0027481308 scopus 로고
    • Stroma-supported immunocytometric assay (SIA): A novel method for testing the sensitivity of acute lymphoblastic leukemia cells to cytotoxic drugs
    • D. Campana, A. Manabe, and W. E. Evans. Stroma-supported immunocytometric assay (SIA): a novel method for testing the sensitivity of acute lymphoblastic leukemia cells to cytotoxic drugs. Leukemia 7:482-8 (1993).
    • (1993) Leukemia , vol.7 , pp. 482-488
    • Campana, D.1    Manabe, A.2    Evans, W.E.3
  • 7
    • 0028357173 scopus 로고
    • Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry
    • Review
    • W. G. Telford, L. E. King, and P. J. Fraker. Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry. [Review]. Journal of Immunological Methods 172:1-16 (1994).
    • (1994) Journal of Immunological Methods , vol.172 , pp. 1-16
    • Telford, W.G.1    King, L.E.2    Fraker, P.J.3
  • 8
    • 42549173580 scopus 로고
    • Pharmacological inhibition of programmed lymphocyte death
    • G. Kroemer and C. Martinez. Pharmacological inhibition of programmed lymphocyte death [see comments]. Immunology Today 15:235-42 (1994).
    • (1994) Immunology Today , vol.15 , pp. 235-242
    • Kroemer, G.1    Martinez, C.2
  • 9
    • 0019929362 scopus 로고
    • Hormone-induced cell death. Purification ad properties of thymocytes undergoing apoptosis after glucocorticoid treatment
    • A. H. Wyllie and R. G. Morris. Hormone-induced cell death. Purification ad properties of thymocytes undergoing apoptosis after glucocorticoid treatment. American Journal of Pathology 109:78-87 (1982).
    • (1982) American Journal of Pathology , vol.109 , pp. 78-87
    • Wyllie, A.H.1    Morris, R.G.2
  • 10
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • A. H. Wyllie. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-6 (1980).
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 11
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • V. A. Fadok, D. R. Voelker, P. A. Campbell, J. J. Cohen, D. L. Bratton, and P. M. Henson. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. Journal of Immunology 148:2207-16 (1992).
    • (1992) Journal of Immunology , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 12
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • G. Koopman, C. P. Reutelingsperger, G. A. Kuijten, R. M. Keehnen, S. T. Pals, and O. M. van. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84:1415-20 (1994).
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pals, S.T.5    Van, O.M.6
  • 13
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • I. Vermes, C. Haanen, N. H. Steffens, and C. Reutelingsperger. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. Journal of Immunological Methods 184:39-51 (1995).
    • (1995) Journal of Immunological Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens, N.H.3    Reutelingsperger, C.4
  • 16
    • 0028973126 scopus 로고
    • Membrane permeabilization by alpha-helical peptides: A flow cytometry study
    • P. Midoux, R. Mayer, and M. Monsigny. Membrane permeabilization by alpha-helical peptides: a flow cytometry study. Biochimica et Biophysica Acta 1239:249-56 (1995).
    • (1995) Biochimica et Biophysica Acta , vol.1239 , pp. 249-256
    • Midoux, P.1    Mayer, R.2    Monsigny, M.3
  • 17
    • 0028325262 scopus 로고
    • Evaluation of methods for measuring cellular glutathione content using flow cytometry
    • D. W. Hedley and S. Chow. Evaluation of methods for measuring cellular glutathione content using flow cytometry. Cytometry 15:349-58 (1994)
    • (1994) Cytometry , vol.15 , pp. 349-358
    • Hedley, D.W.1    Chow, S.2
  • 18
    • 0025580251 scopus 로고
    • Flow cytometric techniques for measurement of cytochrome P-450 activity in viable cells
    • A. D. Miller. Flow cytometric techniques for measurement of cytochrome P-450 activity in viable cells. Methods in Cell Biology 33:71-9 (1990).
    • (1990) Methods in Cell Biology , vol.33 , pp. 71-79
    • Miller, A.D.1
  • 19
    • 0029944386 scopus 로고    scopus 로고
    • A new method of "in-cell reverse transcriptase-polymerase chain reaction" for the detection of BCR/ABL transcript in chronic myeloid leukemia patients
    • N. Testoni, G. Martinelli, P. Farabegoli, A. Zaccaria, M. Amabile, D. Raspadori, S. Pelliconi, E. Zuffa, C. Carboni, and S. Tura. A new method of "in-cell reverse transcriptase-polymerase chain reaction" for the detection of BCR/ABL transcript in chronic myeloid leukemia patients. Blood 87:3822-7 (1996).
    • (1996) Blood , vol.87 , pp. 3822-3827
    • Testoni, N.1    Martinelli, G.2    Farabegoli, P.3    Zaccaria, A.4    Amabile, M.5    Raspadori, D.6    Pelliconi, S.7    Zuffa, E.8    Carboni, C.9    Tura, S.10
  • 20
    • 0027201999 scopus 로고
    • Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometry
    • B. K. Patterson, M. Till, P. Otto, C. Goolsby, M. R. Furtado, L. J. McBride, and S. M. Wolinsky. Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometry. Science 260:976-9 (1993).
    • (1993) Science , vol.260 , pp. 976-979
    • Patterson, B.K.1    Till, M.2    Otto, P.3    Goolsby, C.4    Furtado, M.R.5    McBride, L.J.6    Wolinsky, S.M.7
  • 22
    • 0025580763 scopus 로고
    • Rapid determination of cellular resistance-related drug efflux in tumor cells
    • A. Krishan. Rapid determination of cellular resistance-related drug efflux in tumor cells. Methods in Cell Biology 33:491-500 (1990).
    • (1990) Methods in Cell Biology , vol.33 , pp. 491-500
    • Krishan, A.1
  • 23
    • 0029100327 scopus 로고
    • Heterogeneity of anthracycline retention and response to efflux blockers in human tumors
    • A. Krishan. Heterogeneity of anthracycline retention and response to efflux blockers in human tumors. Cytometry 21:72-5 (1995).
    • (1995) Cytometry , vol.21 , pp. 72-75
    • Krishan, A.1
  • 24
    • 0022354385 scopus 로고
    • Differences in the pharmacokinetics of daunomycin in normal and leukemic rats
    • K. Nooter, P. Sonneveld, and A. Martens. Differences in the pharmacokinetics of daunomycin in normal and leukemic rats. Cancer Research 45:4020-5 (1985).
    • (1985) Cancer Research , vol.45 , pp. 4020-4025
    • Nooter, K.1    Sonneveld, P.2    Martens, A.3
  • 27
    • 0029037943 scopus 로고
    • Flow cytometric assessment of the cellular pharmacokinetics of fluorescent drugs
    • M. S. Dordal, A. C. Ho, S. M. Jackson, Y. F. Fu, C. L. Goolsby, and J. N. Winter. Flow cytometric assessment of the cellular pharmacokinetics of fluorescent drugs. Cytometry 20:307-14 (1995).
    • (1995) Cytometry , vol.20 , pp. 307-314
    • Dordal, M.S.1    Ho, A.C.2    Jackson, S.M.3    Fu, Y.F.4    Goolsby, C.L.5    Winter, J.N.6
  • 28
    • 0024381795 scopus 로고
    • A flow cytometric method for the detection of the development of antibody to Orthoclone OKT3
    • V. L. Lim, M. Gumbert, and M. R. Garovoy. A flow cytometric method for the detection of the development of antibody to Orthoclone OKT3. Journal of Immunological Methods 121:197-201 (1989).
    • (1989) Journal of Immunological Methods , vol.121 , pp. 197-201
    • Lim, V.L.1    Gumbert, M.2    Garovoy, M.R.3
  • 29
    • 0026021448 scopus 로고
    • An improved method for the detection of soluble interleukin 2 receptors in liver transplant recipients by flow cytometry
    • N. Cohen, M. Gumbert, J. Birnbaum, V. L. Lim, D. Falco, N. Ascher, J. Roberts, and M. R. Garovoy. An improved method for the detection of soluble interleukin 2 receptors in liver transplant recipients by flow cytometry. Transplantation 51:417-21 (1991).
    • (1991) Transplantation , vol.51 , pp. 417-421
    • Cohen, N.1    Gumbert, M.2    Birnbaum, J.3    Lim, V.L.4    Falco, D.5    Ascher, N.6    Roberts, J.7    Garovoy, M.R.8
  • 30
    • 0028689539 scopus 로고
    • Flow microsphere immunoassay for the quantitative and simultaneous detection of multiple soluble analytes
    • T. M. McHugh. Flow microsphere immunoassay for the quantitative and simultaneous detection of multiple soluble analytes. Methods in Cell Biology (1994).
    • (1994) Methods in Cell Biology
    • McHugh, T.M.1
  • 31
    • 0028296673 scopus 로고
    • Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits
    • W. Piekoszewski, F. S. Chow, and W. J. Jusko. Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits. Journal of Pharmacology & Experimental Therapeutics 269:103-9 (1994).
    • (1994) Journal of Pharmacology & Experimental Therapeutics , vol.269 , pp. 103-109
    • Piekoszewski, W.1    Chow, F.S.2    Jusko, W.J.3
  • 32
    • 0028246872 scopus 로고
    • Inhibition of rat splenocyte proliferation with methylprednisolone: In vivo effect of liposomal formulation
    • E. V. Mishina and W. J. Jusko. Inhibition of rat splenocyte proliferation with methylprednisolone: in vivo effect of liposomal formulation. Pharmaceutical Research 11:848-54 (1994).
    • (1994) Pharmaceutical Research , vol.11 , pp. 848-854
    • Mishina, E.V.1    Jusko, W.J.2
  • 33
  • 34
    • 0030576981 scopus 로고    scopus 로고
    • A new method for measuring lymphoproliferation at the single-cell level in whole blood cultures by flow cytometry
    • H. Gaines, L. Andersson, and G. Biberfeld. A new method for measuring lymphoproliferation at the single-cell level in whole blood cultures by flow cytometry. Journal of Immunological Methods 195:63-72 (1996).
    • (1996) Journal of Immunological Methods , vol.195 , pp. 63-72
    • Gaines, H.1    Andersson, L.2    Biberfeld, G.3
  • 35
    • 0029034013 scopus 로고
    • Rapid flow cytometric method for measuring lymphocyte subset activation
    • V. C. Maino, M. A. Suni, and J. J. Ruitenberg. Rapid flow cytometric method for measuring lymphocyte subset activation. Cytometry 20:127-33 (1995).
    • (1995) Cytometry , vol.20 , pp. 127-133
    • Maino, V.C.1    Suni, M.A.2    Ruitenberg, J.J.3
  • 37
    • 0030012605 scopus 로고    scopus 로고
    • Utility of flow cytometric detection of CD69 expression as a rapid method for determining polyand oligoclonal lymphocyte activation
    • P. E. Simms and T. M. Ellis. Utility of flow cytometric detection of CD69 expression as a rapid method for determining polyand oligoclonal lymphocyte activation. Clinical & Diagnostic Laboratory Immunology 3:301-4 (1996).
    • (1996) Clinical & Diagnostic Laboratory Immunology , vol.3 , pp. 301-304
    • Simms, P.E.1    Ellis, T.M.2
  • 39
    • 0026513149 scopus 로고
    • Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level
    • J. Andersson, S. Nagy, C. G. Groth, and U. Andersson. Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level. Immunology 75:136-42 (1992).
    • (1992) Immunology , vol.75 , pp. 136-142
    • Andersson, J.1    Nagy, S.2    Groth, C.G.3    Andersson, U.4
  • 40
    • 0030444799 scopus 로고    scopus 로고
    • Drug delivery issues in vaccine development
    • M. F. Powell. Drug delivery issues in vaccine development [Review]. Pharmaceutical Research 13:1777-1785 (1996).
    • (1996) Pharmaceutical Research , vol.13 , pp. 1777-1785
    • Powell, M.F.1
  • 41
    • 0027195578 scopus 로고
    • Cytokine regulation of T-cell function: Potential for therapeutic intervention
    • F. Powrie and R. L. Coffman. Cytokine regulation of T-cell function: potential for therapeutic intervention. Trends in Pharmacological Sciences. 14:164-8 (1993).
    • (1993) Trends in Pharmacological Sciences , vol.14 , pp. 164-168
    • Powrie, F.1    Coffman, R.L.2
  • 43
    • 0029586280 scopus 로고
    • Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies
    • C. Prussin and D. D. Metcalfe. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. Journal of Immunological Methods 188:117-28 (1995).
    • (1995) Journal of Immunological Methods , vol.188 , pp. 117-128
    • Prussin, C.1    Metcalfe, D.D.2
  • 44
  • 45
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • M. A. Goodell, K. Brose, G. Paradis, A. S. Conner, and R. C. Mulligan. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. Journal of Experimental Medicine 183:1797-806 (1996).
    • (1996) Journal of Experimental Medicine , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 46
    • 0027855043 scopus 로고
    • In vivo and in vitro characterization of long-term repopulating primitive hematopoietic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection
    • N. S. Wolf, A. Kone, G. V. Priestley, and S. H. Bartelmez. In vivo and in vitro characterization of long-term repopulating primitive hematopoietic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection. Experimental Hematology 21:614-22 (1993).
    • (1993) Experimental Hematology , vol.21 , pp. 614-622
    • Wolf, N.S.1    Kone, A.2    Priestley, G.V.3    Bartelmez, S.H.4
  • 47
    • 0029819565 scopus 로고    scopus 로고
    • Isolation of primitive human bone marrow hematopoietic progenitor cells using Hoechst 33342 and Rhodamine 123
    • T. Leemhuis, M. C. Yoder, S. Grigsby, B. Aguero, P. Eder, and E. F. Srour. Isolation of primitive human bone marrow hematopoietic progenitor cells using Hoechst 33342 and Rhodamine 123. Experimental Hematology 24:1215-24 (1996).
    • (1996) Experimental Hematology , vol.24 , pp. 1215-1224
    • Leemhuis, T.1    Yoder, M.C.2    Grigsby, S.3    Aguero, B.4    Eder, P.5    Srour, E.F.6
  • 48
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • M. Chalfie, Y. Tu, G. Euskirchen, W. W. Ward, and D. C. Prasher. Green fluorescent protein as a marker for gene expression. Science 263:802-5 (1994).
    • (1994) Science , vol.263 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5
  • 52
    • 0028921834 scopus 로고
    • Improved green fluorescence
    • R. Heim, A. B. Cubitt, and R. Y. Tsien. Improved green fluorescence [letter]. Nature 373:663-4 (1995).
    • (1995) Nature , vol.373 , pp. 663-664
    • Heim, R.1    Cubitt, A.B.2    Tsien, R.Y.3
  • 53
    • 0029973636 scopus 로고    scopus 로고
    • FACS-optimized mutants of the green fluorescent protein (GFP)
    • B. P. Cormack, R. H. Valdivia, and S. Falkow. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173:33-8 (1996).
    • (1996) Gene , vol.173 , pp. 33-38
    • Cormack, B.P.1    Valdivia, R.H.2    Falkow, S.3
  • 56
    • 0028114572 scopus 로고
    • Patterns of intracellular compartmentalization, trafficking and acidification of 5′-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells
    • J. L. Tonkinson and C. A. Stein. Patterns of intracellular compartmentalization, trafficking and acidification of 5′-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells. Nucleic Acids Research 22:4268-75 (1994).
    • (1994) Nucleic Acids Research , vol.22 , pp. 4268-4275
    • Tonkinson, J.L.1    Stein, C.A.2
  • 58
    • 0029819705 scopus 로고    scopus 로고
    • Oligonucleotide uptake in human hematopoietic cells is increased in leukemia and is related to cellular activation
    • Q. Zhao, X. Song, T. Waldschmidt, E. Fisher, and A. M. Krieg. Oligonucleotide uptake in human hematopoietic cells is increased in leukemia and is related to cellular activation. Blood 88:1788-95 (1996).
    • (1996) Blood , vol.88 , pp. 1788-1795
    • Zhao, Q.1    Song, X.2    Waldschmidt, T.3    Fisher, E.4    Krieg, A.M.5
  • 60
    • 0027985329 scopus 로고
    • Stage-specific oligonucleotide uptake in murine bone marrow B-cell precursors
    • Q. Zhao, T. Waldschmidt, E. Fisher, C. J. Herrera, and A. M. Krieg. Stage-specific oligonucleotide uptake in murine bone marrow B-cell precursors. Blood 84:3660-6 (1994).
    • (1994) Blood , vol.84 , pp. 3660-3666
    • Zhao, Q.1    Waldschmidt, T.2    Fisher, E.3    Herrera, C.J.4    Krieg, A.M.5
  • 61
    • 0028705254 scopus 로고
    • Calibration of flow cytometer detector systems
    • R. E. Durand. Calibration of flow cytometer detector systems. Methods in Cell Biology 42:597-604 (1994).
    • (1994) Methods in Cell Biology , vol.42 , pp. 597-604
    • Durand, R.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.