Angiotensin II signal transduction in vascular smooth muscle cells: Role of tyrosine kinases

Keio Journal of Medicine

Volumn 46, Issue 2, 1997, Pages 61-68

  Ishida, Mari ^a   Berk, Bradford C ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Angiotensin II; Signal transduction; Tyrosine kinase; Vascular smooth muscle

Indexed keywords

ANGIOTENSIN; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ATHEROSCLEROSIS; BLOOD PRESSURE REGULATION; BLOOD VESSEL TONE; CARDIOVASCULAR DISEASE; CONGESTIVE HEART FAILURE; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION; HEMOSTASIS; HYPERTENSION; NONHUMAN; ONCOGENE C FOS; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; PROTO ONCOGENE; REVIEW; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; VASCULAR SMOOTH MUSCLE;

EID: 0030749622     PISSN: 00229717     EISSN: None     Source Type: Journal    
DOI: 10.2302/kjm.46.61     Document Type: Review

References (86)

1. Skeggs LT Jr, Marsh WH, Kahn JR, Shumway NP: The purification of hypertensin I. J Exper Med 1954; 100: 363-370
2. Berk BC, Vekshtein V, Gordon HM, Tsuda T: Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells. Hypertension 1989; 13: 305-314
3. Geisterfer AA, Peach MJ, Owens GK: Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ Res 1988; 62: 749-756
4. 2 in cultured rat mesangial cells. Am J Physiol (Cell Physiol) 1987; 253: C113-C120
5. Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW: Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74: 1141-1148
6. 2+ mobilization and protein kinase C activation. J Biol Chem 1989; 264: 526-530
7. SOLVD Investigators: Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991; 325: 293-302
8. Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ Jr, Cuddy TE, Davis BR, Geltman EM, Goldman S, Flaker GC: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. N Engl J Med 1992; 327: 669-677
9. Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE: Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature 1991; 351: 233-236
10. Sasaki K, Yamamo Y, Bardham S, Iwai N, Murray JJ, Hasegawa M, Matsuda Y, Inagami T: Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin type-1 receptor. Nature 1991; 351: 230-233
11. Ji H, Leung M, Zhang Y, Catt KJ, Sandberg K: Differential structural requirements for specific binding of nonpeptide and peptide antagonists to the AT1 angiotensin receptor. Identification of amino acid residues that determine binding of the antihypertensive drug losartan. J Biol Chem 1994; 269: 16533-16536
12. Noda K, Saad Y, Kinoshita A, Boyle TP, Graham RM, Husain A, Karnik SS: Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms. J Biol Chem 1995; 270: 2284-2289
13. Bihoreau C, Monnot C, Davies E, Teutsch B, Bernstein KE, Corvol P, Clauser E: Mutation of Asp74 of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling. Proc Natl Acad Sci USA 1993; 90: 5133-5137
14. Yamano Y, Ohyama K, Kikyo M, Sano T, Nakagomi Y, Inoue Y, Nakamura N, Morishima I, Guo DF, Hamakubo T, Inagami T: Mutagenesis and the molecular modeling of the rat angiotensin II receptor (AT1). J Biol Chem 1995; 270: 14024-14030
15. Marie J, Maigret B, Joseph MP, Larguier R, Nouet S, Lombard C, Bonnafous JC: Tyr292 in the seventh transmembrane domain of the AT1A angiotensin II receptor is essential for its coupling to phospholipase C. J Biol Chem 1994; 269: 20815-20818
16. Shirai H, Takahashi K, Katada T, Inagami T: Mapping of G protein coupling sites of the angiotensin II type 1 receptor. Hypertension 1995; 25: 726-730
17. Ohyama K, Yamano Y, Chaki S, Kondo T, Inagami T: Domains for G-protein coupling in angiotensin II receptor type I: studies by site-directed mutagenesis. Bioehem Biophys Res Commun 1992; 189: 677-683
18. Hunyady L, Bor M, Balla T, Catt KJ: Critical role of a conserved intramembrane tyrosine residue in angiotensin II receptor activation. J Biol Chem 1995; 270: 9702-9705
19. Griendling KK, Rittenhouse SE, Brock TA, Ekstein LS, Gimbrone MA Jr, Alexander RW: Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells. J Biol Chem 1986; 261: 5901-5906
20. Brock TA, Alexander RW, Ekstein LS, Atkinson WJ, Gimbrone MA Jr: Angiotensin increases cytosolic free calcium in cultured vascular smooth muscle cells. Hypertension 1985; 7: I-105-I-109
21. Griendling KK, Tsuda T, Berk BC, Alexander RW: Angiotensin II stimulation of vascular smooth muscle cells. Secondary signalling mechanisms. Am J Hypertens 1989; 2: 659-665
22. Huckle WR, Prokop CA, Dy RC, Herman B, Earp S: Angiotensin II stimulates protein-tyrosine phosphorylation in a calcium-dependent manner. Mol Cell Biol 1990; 10: 6290-6298
23. Huckle WR, Dy RC, Earp HS: Calcium-dependent increase in tyrosine kinase activity stimulated by angiotensin II. Proc Natl Acad Sci USA 1992; 89: 8837-8841
24. Molloy CJ, Taylor DS, Weber H: Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells. J Biol Chem 1993; 268: 7338-7345
25. Duff JL, Berk BC, Corson MA: Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells. Biochem Biophys Res Commun 1992; 188: 257-264
26. Tsuda T, Kawahara Y, Ishida Y, Koide M, Shii K, Yokoyama M: Angiotensin II stimulates two myelin basic protein/microtubule-associated protein 2 kinases in cultured vascular smooth muscle cells. Circ Res 1992; 71: 620-630
27. Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE: Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor. Nature 1995; 375: 247-250
28. Hollenberg MD: Thyrosine kinase pathways and the regulation of smooth muscle contractility. Trends Pharmacol Sci 1994; 15: 108-114
29. Leduc I, Haddad P, Giasson E, Meloche S: Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells. Mol Pharmacol 1995; 48: 582-592
30. Premont RT, Inglese J, Lefkowitz RJ: Protein kinases that phosphorylate activated G protein-coupled receptors. Faseb J 1995; 9: 175-182
31. Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG: G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins. Cold Spring Harb Symp Quant Biol 1992; 57: 127-133
32. 1 receptor is tyrosine and serine phosphorylated and can serve as a substrate for the SRC family of tyrosine kinases. Biochem Biophys Res Commun 1994; 200: 260-267
33. Kai H, Griendling KK, Lassegue B, Ollerenshaw JD, Runge MS, Alexander RW: Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor. Hypertension 1994; 24: 523-527
34. Oppermann M, Freedman NJ, Alexander RW, Lefkowitz RJ: Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C. J Biol Chem 1996; 271: 13266-13272
35. Crespo P, Xu N, Simonds WF, Gutkind JS: Ras-dependent activation of MAP kinase pathway mediated by G-protein β γ subunits. Nature 1994; 369: 418-420
36. βγ, subunits and lipid. J Biol Chem 1995; 270: 11707-11710
37. Marrero MB, Schieffer B, Paxton WG, Duff JL, Berk BC, Bernstein KE: The role of tyrosine phosphorylation in angiotensin II-mediated intracellular signalling. Cardiovasc Res 1995; 30: 530-536
38. Hunyady L, Bor M, Baukal AJ, Balla T, Catt KJ: A conserved NPLFY sequence contributes to agonist binding and signal transduction but is not an internalization signal for the type 1 angiotensin II receptor. J Biol Chem 1995; 270: 16602-16609
39. Laporte SA, Servant G, Richard DE, Escher E, Guillemette G, Leduc R: The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization. Mol Pharmacol 1996; 49: 89-95
40. Pascal SM, Singer AU, Gish G, Yamazaki T, Shoelson SE, Pawson T, Kay LE, Forman Kay JD: Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-γ 1 complexed with a high affinity binding peptide. Cell 1994; 77: 461-172
41. Fantl WJ, Johnson DE, Williams LT: Signalling by receptor tyrosine kinases. Annu Rev Biochem 1993; 62: 453-481
42. Bolen JB, Rowley RB, Spana C, Tsygankov AY: The Src family of tyrosine protein kinases in hemopoietic signal transduction. Faseb J 1992; 6: 3403-3409
43. c-src in vascular smooth muscle cells. Circ Res 1995; 77: 1053-1059
44. c-src antibodies inhibits the angiotensin II activation of phospholipase C-γ1 in rat aortic smooth muscle cells. J Biol Chem 1995; 270: 15734-15738
45. Sadoshima J, Izumo S: The heterotrimeric Gq protein-coupled angiotensin II receptor activates p21ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J 1996; 15: 775-787
46. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O: Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem Sci 1994; 19: 222-227
47. Pleiman CM, Clark MR, Gauen LK, Winitz S, Coggeshall KM, Johnson GL, Shaw AS, Cambier JC: Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-γ 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase. Mol Cell Biol 1993; 13: 5877-5887
48. Darnell JE Jr, Kerr IM, Stark GR: Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-1421
49. Bhat GJ, Thekkumkara TJ, Thomas WG, Conrad KM, Baker KM: Angiotensin II stimulates sis-inducing factor-like DNA binding activity. Evidence that the AT 1A receptor. J Biol Chem 1994; 269: 31443-31449
50. Rodriguez-Linares B, Watson SP: Phosphorylation of JAK2 in thrombin-stimulated human platelets. FEBS Lett 1994; 352: 335-338
51. Polte TR, Naftilan AJ, Hanks SK: Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II. J Cell Biochem 1994; 55: 106-119
52. Leduc I, Meloche S: Angiotensin II stimulates tyrosine phosphorylation of the focal adhesion-associated protein paxillin in aortic smooth muscle cells. J Biol Chem 1995; 270: 4401-4404
53. Turner CE, Pietras KM, Taylor DS, Molloy CJ: Angiotensin II stimulation of rapid paxillin tyrosine phosphorylation correlates with the formation of focal adhesions in rat aortic smooth muscle cells. J Cell Sci 1995; 108: 333-342
54. Okuda M, Kawahara Y, Nakayama I, Hoshijima M, Yokoyama M: Angiotensin II transduces its signal to focal adhesions via angiotensin II type 1 receptors in vascular smooth muscle cells. FEBS Lett 1995; 368: 343-347
55. FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol 1992; 119: 893-903
56. Turner CE, Schaller MD, Parsons JT: Tyrosine phosphorylation of the focal adhesion kinase pp125FAK during development: relation to paxillin. J Cell Sci 1993; 105: 637-645
57. Calalb MB, Polte TR, Hanks SK: Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol Cell Biol 1995; 15: 954-963
58. Sabe H, Hata A, Okada M, Nakagawa H, Hanafusa H: Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src. Proc Natl Acad Sci USA 1994; 91: 3984-3988
59. Yamaguchi R, Maki M, Hatanaka M, Sabe H: Unphosphorylated and tyrosine-phosphorylated forms of a focal adhesion protein, paxillin, are substrates for calpain II in vitro: implications for the possible involvement of calpain II in mitosis-specific degradation of paxillin. FEBS Lett 1994; 356: 114-116
60. Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT: Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol Cell Biol 1994; 14: 1680-1688
61. Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J: Protein tyrosine kinase PYKG involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. Nature 1995; 376: 737-745
62. Sasaki H, Nagura K, Ishino M, Tobioka H, Kotani K, Sasaki T: Cloning and characterization of cell adhesion kinase β, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily. J Biol Chem 1995; 270: 21206-21219
63. Daub H, Weiss FU, Wallasch C, Ullrich A: Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996; 379: 557-560
64. Linseman DA, Benjamin CW, Jones DA: Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells. J Biol Chem 1995; 270: 12563-12568
65. Stitt TN, Conn G, Gore M, Lai C, Bruno J, Radziejewski C, Mattsson K, Fisher J, Gies DR, Jones PF, Masiakowski P, Ryan TE, Nancy JT, Chen DH, DiStefano PS, Long GL, Basiico C, Goldfarb MP, Lemke G, Glass DJ, Yancopoulos GD: The anti-coagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. Cell 1995; 80: 661-670
66. O'Bryan JP, Frye RA, Cogswell PC, Neubauer A, Kitch B, Prokop C, Espinosa R, Le Beau MM, Earp HS, Liu ET: Axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol 1991; 11: 5016-5031
67. Li R, Chen J, Hammonds G, Phillips H, Armanini M, Wood P, Bunge R, Godowski PJ, Sliwkowski MX, Mather JP: Identification of Gas6 as a growth factor for human Schwann cells. J Neurosci 1996; 16: 2012-2019
68. Ling L, Kung HJ: Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase. Mol Cell Biol 1995; 15: 6582-6592
69. 2+-mobilizing growth factors. J Biol Chem 1995; 270: 5702-5705
70. Rhee SG, Choi KD: Regulation of inositol phospholipid-specific phospholipase C isozymes. J Biol Chem 1992; 267: 12393-12396
71. Smrcka AV, Hepler JR, Brown KO, Sternweis PC: Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science 1991; 251: 804-807
72. Taylor SJ, Chae HZ, Rhee SG, Exton JH: Activation of the β 1 isozyme of phospholipase C by α subunits of the Gq class of G proteins. Nature 1991, 350: 516-518
73. Kim HK, Kim JW, Zilberstein A, Margolis B, Kim JG, Schlessinger J, Rhee SG: PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ 1 phosphorylation on tyrosine residues 783 and 1254. Cell 1991; 65: 435-141
74. Marrero MB, Paxton W, Duff JL, Berk BC, Bernstein KE: Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-γ1 in vascular smooth muscle cells. J Biol Chem 1994; 269: 10935-10939
75. Chao TS, Foster DA, Rapp UR, Rosner MR: Differential raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium. J Biol Chem 1994; 269: 7337-7341
76. Butcher RD, Schollmann C, Marme D: Angiotensin II mediates intracellular signalling in vascular smooth muscle cells by activation of tyrosine-specific protein kinases and c-raf-1. Biochem Biophys Res Commun 1993; 196: 1280-1287
77. Force T, Kyriakis JM, Avruch J, Bonventre JV: Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells. J Biol Chem 1991; 266: 6650-6656
78. Fabian JR, Daar IO, Morrison DK: Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol Cell Biol 1993; 13: 7170-7179
79. Marais R, Light Y, Paterson HF, Marshall CJ: Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. Embo J 1995; 14: 3136-3145
80. Jelinek T, Dent P, Sturgill TW, Weber MJ: Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation. Mol Cell Biol 1996; 16: 1027-1034
81. Schieffer B, Paxton WG, Chai Q, Marrero MB, Bernstein KE: Angiotensin II controls p21ras activity via pp60c-src. J Biol Chem 1996; 271: 10329-10333
82. Touhara K, Hawes BE, van Biesen T, Lefkowitz RJ: G protein β γ subunits stimulate phosphorylation of Shc adapter protein. Proc Natl Acad Sci USA 1995; 92: 9284-9287
83. Schorb W, Peeler TC, Madigan NN, Conrad KM, Baker KM: Angiotensin II-induced protein tyrosine phosphorylation in neonatal rat cardiac fibroblasts. J Biol Chem 1994; 269: 19626-19632
84. Buday L, Downward J: Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell 1993; 73: 611-620
85. Crespo P, Cachero TG, Xu N, Gutkind JS: Dual effect of β adrenergic receptors on mitogen-activated protein kinase. Evidence for a β γ-dependent activation and a G α s-cAMP-mediated inhibition. J Biol Chem 1995; 270: 25259-25265
86. Inglese J, Koch WJ, Touhara K, Lefkowitz RJ: G β γ interactions with PH domains and Ras-MAPK signaling pathways. Trends Biochem Sci 1995; 20: 151-156