Insulin resistance due to hyperglycaemia: An adaptation protecting insulin-sensitive tissues

Diabetologia

Volumn 40, Issue SUPPL. 2, 1997, Pages

  Yki Jarvinen H ^a   Makimattila S ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

CONFERENCE PAPER; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; POSTPRANDIAL STATE; PRIORITY JOURNAL;

DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; GLUCOSE; HEXOSAMINES; HUMANS; HYPERGLYCEMIA; INSULIN RESISTANCE;

EID: 0030748460     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051431     Document Type: Conference Paper

References (32)

1. The Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-986
2. Kuusisto J, Mykkänen L, Pyörälä K, Laakso M (1994) NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes 43: 960-967
3. Lehto S, Rönnemaa T, Pyörälä K, Laakso M (1996) Predictors of stroke in middle-aged patients with non-insulin-dependent diabetes. Stroke 27: 63-68
4. King GL, Kunisaki M, Nishio Y, Inoguchi T, Shiba T, Xia P (1996) Biochemical and molecular mechanisms in the development of vascular complications. Diabetes 45:S105-S108
5. Gerich JE, Mitrakou A, Kelley D. et al. (1990) Contribution of impaired muscle glucose clearance to reduced post-absorptive systemic glucose clearance in NIDDM. Diabetes 39: 211-216
6. Yki-Järvinen H (1992) Glucose toxicity. Endocr Rev 13: 415-431
7. McMahon M, Marsh H, Rizza R (1989) Comparison of the pattern of postprandial carbohydrate metabolism after ingestion of a glucose drink or a mixed meal. J Clin Endocrinol Metab 68: 647-653
8. McMahon M, Marsh HM, Rizza RA (1989) Effects of basal insulin supplementation on disposition of mixed meal in obese patients with NIDDM. Diabetes 38: 291-303
9. Mitrakou A, Kelley D, Veneman T, et al. (1990) Contribution of abnormal muscle and liver metabolism to postprandial hyperglycaemia in NIDDM. Diabetes 39: 1381-1390
10. Dinneen S, Gerich J, Rizza R (1992) Carbohydrate metabolism in non-insulin-dependent diabetes mellitus. N Engl J Med 327: 707-713
11. Cherrington AD, Stevenson RV, Steiner KE, et al. (1987) Insulin, glucagon, and glucose as regulators of hepatic glucose uptake and production in vivo. Diabetes Metab Rev 3: 307-332
12. Yki-Järvinen H, Koivisto VA (1986) Natural course of insulin resistance in type 1 diabetes. N Engl J Med 315: 224-230
13. Lillioja S, Mott DM, Howard BV, et al. (1988) Impaired glucose tolerance as a disorder of insulin action. Longitudinal and cross-sectional studies in Pima Indians. N Engl J Med 318: 1217-1225
14. Vuorinen-Markkola H, Koivisto VA, Yki-Järvinen H (1992) Mechanisms of hyperglycaemia-induced insulin resistance in whole body and skeletal muscle of type 1 diabetic patients. Diabetes 41: 571-580
15. Yki-Järvinen H, Helve E, Koivisto VA (1987) Hyperglycaemia decreases glucose uptake in type 1 diabetes. Diabetes 36: 892-896
16. DeFronzo RA, Gunnarsson R, Björkman O, Olsson M, Wahren J (1985) Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest 76: 149-155
17. Yki-Järvinen H, Sahlin K, Ren JM, Koivisto VA (1990) Localization of the rate-limiting defect for glucose disposal in skeletal muscle of insulin-resistant type 1 diabetic patients. Diabetes 39: 157-167
18. Mäkimattila S, Virkamäki A, Malmström R, Utriainen T, Yki- Järvinen H (1996) Insulin resistance in type I diabetes mellitus: A major role for reduced glucose extraction. J Clin Endocrinol Metab 81: 707-712
19. Utriainen T, Malmström R, Mäkimattila S, Yki-Järvinen H (1995) Methodological aspects, dose-response characteristics and causes of interindividual variation in insulin stimulation of limb blood flow in normal subjects. Diabetologia 38: 555-564
20. Zierath JR, Galuska D, Nolle LA, Thörne A, Kristensen JS, Wallberg-Henriksson H (1994) Effect of glycaemia on glucose transport in isolated skeletal muscle from patients with NIDDM: in vitro reversal of muscular insulin resistance. Diabetologia 37: 270-277
21. Marshall S, Bacote V, Traxinger RR (1991) Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266: 4706-4712
22. Kornfeld R (1967) Studies on L-glutamine D-fructose 6-phophate amidotransferase. I. Feedback inhibition by uridine diphosphate-N- acetylglucosamine. J Biol Chem 242: 3135-3141
23. Hebert LF Jr., Daniels MC, Zhou J, et al. (1996) Overexpression of glutamine: fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance. J Clin Invest 98: 930-936
24. Robinson KA, Weinstein ML, Lindenmayer GE, Buse MG (1995) Effects of diabetes and hyperglycaemia on the hexosamine synthesis pathway in rat muscle and liver. Diabetes 44: 1438-1446
25. Rossetti L, Hawkins M, Chen W, Gindi J, Barzilai N (1995) In vivo glucosamine infusion induces insulin resistance in normoglycaemic but not in hyperglycaemic conscious rats. J Clin Invest 96: 132-140
26. Yki-Järvinen H, Daniels MC, Virkamäki A, Mäkimattila S, DeFronzo RA, McClain D (1996) Increased glutamine: fructose-6-phosphate amidotransferase activity in skeletal muscle of patients with NIDDM. Diabetes 45: 302-307
27. Haltiwanger RS, Kelly WG, Roquemore EP, et al. (1992) Glycosylation of nuclear and cytoplasmic proteins is ubiquitous and dynamic. Biochemical Society Transactions 20: 264-269
28. Dinter A, Berger EG (1995) The regulation of cell- and tissue-specific expression of glycans by glycosyltransferases. Adv Exp Med Biol 376: 53-82
29. Hart GW (1992) Glycosylation. Curr Opin Cell Biol 4: 1017-1023
30. Baron AD, Zhu J-S, Zhu J-H, Weldon H, Maianu L, Garvey WT (1995) Glucosamine induces insulin resistance in vivo by affecting GLUT4 translocation in skeletal muscle. J Clin Invest 96: 2792-2801
31. Haltiwanger RS, Blomberg MA, Hart GW (1992) Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetyl-glucosamine: polypeptide beta-N-acetylglucosaminyltransferase. J Biol Chem 267: 9005-9013
32. Daniels MC, Ciaraldi TP, Nikoulina S, Henry RR, McClain DA (1996) Glutamine: fructose-6-phosphate amidotransferase activity in cultured human skeletal muscle cells: relationship to glucose disposal rate in control and non-insulin-dependent diabetes mellitus subjects and regulation by glucose and insulin. J Clin Invest 97: 1235-1241