The comparative interaction of quinonoid (6R)-dihydrobiopterin and an alternative dihydropterin substrate with wild-type and mutant rat dihydropteridine reductases

Biochemistry

Volumn 36, Issue 31, 1997, Pages 9438-9445

  Kiefer, Philip M ^a,b,c   Grimshaw, Charles E ^a   Whiteley, John M ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROBIOPTERIN; DIHYDROPTERIDINE REDUCTASE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE MUTATION; ISOMERISM; MULTIGENE FAMILY; PRIORITY JOURNAL;

ANIMALS; BIOPTERIN; DIHYDROPTERIDINE REDUCTASE; MUTATION; PTERINS; RATS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

FELIS CATUS;

EID: 0030741222     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970585i     Document Type: Article

References (29)

1. Armarego, W. L. F., Randles, D., & Taguchi, H. (1983) Eur. J. Biochem. 135, 393-403.
2. Armarego, W. L. F., Randles, D., & Waring, P. (1984) Med. Rev. 4, 267-321.
3. Askenes, A., & Ljones, T. (1980) Arch. Biochem. Biophys. 202, 342-347.
4. Blakley, R. L. (1969) in Frontiers of Biology (Newberger, A., & Tatum, E. L., Eds.) pp 62-63, John Wiley & Sons, Inc., New York.
5. Cleland, W. W. (1979) in Methods in Enzymology, Vol 63 (Purich, D. L., Ed.) pp 103-138, Academic Press, San Diego.
6. Fersht, A. (1985) in Enzyme Structure and Mechanism, W. H. Freeman & Co., New York.
7. Jörnvall, H., Persson, B., Krook, M., Atrian, S., Gonzàlez-Duarte, R., Jeffery, J., & Ghosh, D. (1995) Biochemistry 34, 6003-6013.
8. Kaufman, S., & Kaufman, E. E. (1985) in Folates and Pterins (Blakley, R. L., & Benkovic, S. J., Eds.) pp 251-352, John Wiley and Sons, Inc., New York.
9. Kaufman, S., Holtzman, N. A., Milstein, S., Butler, I. J., & Krumholz, A. (1975) N. Engl. J. Med. 293, 785-790.
10. Kiefer, P. M. (1996) Ph.D. Thesis, University of California at San Diego.
11. Kiefer, P. M., Varughese, K. I., Su, Y., Xuong, N. H., Chang, C. F., Gupta, P., Bray, T., & Whiteley, J. M. (1996) J. Biol. Chem. 271, 3437-3444.
12. Klinman, J. P. (1978) in Transition States of Biochemical Processes (Gandour, R. D., & Schowen, R. L., Eds.) pp 165-200, Plenum Press, New York.
13. Kuhn, D. M., & Lowenberg, W. (1985) in Folates and Pterins (Blakley, R. L., & Benkovic, S. J., Eds.) John Whiley and Sons, Inc., New York.
14. Matthews, D. A., Varughese, K. I., Skinner, M., Xuong, N. H., Hoch, J., Trach, K., Schneider, M., Bray, T., & Whiteley, J. M. (1991) Arch. Biochem. Biophys. 287, 234-239.
15. Mckinley-Mckee, J. S., Winberg, J. O., & Petterson, G. (1991) Biochem. Int. 25, 879-885.
16. Orr, G. A., & Blanchard, J. S. (1984) Anal. Biochem. 142, 232-234.
17. Poddar, S., & Henkin, J. (1984) Biochemistry 23, 3143-3148.
18. Pouplana, L. R., & Fothergill-Gilmore, L. A. (1994) Biochemistry 33, 7047-7055.
19. Sakai, N., Kaufman, S., & Milstien, S. (1995) J. Neurochem. 65, 895-902.
20. Shiman, R. (1985) in Folates and Pterins (Blakley, R. L., & Benkovic, S. J., Eds.) pp 179-249, John Wiley & Sons, Inc., New York.
21. Tanaka, N., Nonaka, T., Tanabe, T., Yoshimoto, T., Tsuru, D., & Mitsui, Y. (1996) Biochemistry 35, 7715-7730.
22. Thoden, J. B., Frey, P. A., & Holden, H. M. (1996a) Protein Sci. 5, 2149-2161.
23. Thoden, J. B., Frey, P. A., & Holden, H. M. (1996b) Biochemistry 35, 2557-2566.
24. Thoden, J. B., Frey, P. A., & Holden, H. M. (1996c) Biochemistry 35, 5137-5144.
25. Varughese, K. I., Skinner, M. M., Whiteley, J. M., Matthews, D. A., & Xuong, N. H. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 6080-6084.
26. Varughese, K. I., Xuong, N. H., Kiefer, P. M., Matthews, D. A., & Whiteley, J. M. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 5582-5586.
27. Viola, R. E., Cook, P. F., & Cleland, W. W. (1979) Anal. Biochem. 96, 334-340.
28. Webber, S., Deits, T. L., Snyder, W. R., & Whiteley, J. M. (1978) Anal. Biochem. 84, 491-503.
29. Whiteley, J. M., Varughese, K. I., Xuong, N.-H., & Matthews, D. A. (1993) Pteridines 4, 159-173.