Altered structural and mechanistic properties of mutant dihydropteridine reductases

Journal of Biological Chemistry

Volumn 271, Issue 7, 1996, Pages 3437-3444

  Kiefer, P M ^a   Varughese, K I ^a   Su, Y ^a   Xuong, N H ^a   Chang, C F ^a   Gupta, P ^a   Bray, T ^a   Whiteley, J M ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOENZYME; DIHYDROPTERIDINE REDUCTASE; MUTANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SERINE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ESCHERICHIA COLI; GENETIC ENGINEERING; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN TERTIARY STRUCTURE; PROTON TRANSPORT; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; CRYSTALLIZATION; DIHYDROPTERIDINE REDUCTASE; ESCHERICHIA COLI; KINETICS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; PROTEIN CONFORMATION; RATS; RECOMBINANT PROTEINS;

EID: 0030042793     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.7.3437     Document Type: Article

References (0)