General method for the synthesis of N-methyl amino acids and N-alkyl amino esters from O'Donnell's Schiff bases

Tetrahedron Letters

Volumn 38, Issue 29, 1997, Pages 5085-5086

  Chruma, Jason J ^a   Sames, Dalibor ^a   Polt, Robin ^a  

^a University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; SCHIFF BASE;

ALKYLATION; ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030740169     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01132-5     Document Type: Article

References (22)

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19. 3, filtered through Celite,® reduced via rotary evaporation, and dried overnight in vacuo. Product (2 or 3) purified via flash chromatography. Generally, 5-19% unmethylated secondary amine, and no 1, is recovered.
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