Modulation of agonist-induced phosphoinositide metabolism, Ca2+ signalling and contraction of airway smooth muscle by cyclic AMP-dependent mechanisms

British Journal of Pharmacology

Volumn 117, Issue 3, 1996, Pages 419-426

  Hoiting, B H ^a   Meurs, H ^a   Schuiling, M ^a   Kuipers, R ^a   Elzinga, C R S ^a   Zaagsma, J ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

8 Br cyclic AMP; Airway smooth muscle cells; Contraction; Cyclic AMP; Forskolin; Histamine; Intracellular calcium; Isoprenaline; Methacholine; Phosphoinositide metabolism

Indexed keywords

8 BROMO CYCLIC AMP; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EGTAZIC ACID; FORSKOLIN; HISTAMINE; ISOPRENALINE; LITHIUM CHLORIDE; METHACHOLINE; MUSCARINIC AGENT; PHOSPHATIDYLINOSITIDE;

AIRWAY CONSTRICTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM MOBILIZATION; CATTLE; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; TRACHEA MUSCLE;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM; CATTLE; CELLS, CULTURED; CHOLINERGIC AGENTS; CYCLIC AMP; FORSKOLIN; HISTAMINE; ISOPROTERENOL; METHACHOLINE CHLORIDE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PHOSPHATIDYLINOSITOLS; SIGNAL TRANSDUCTION; TRACHEA;

EID: 0030023755     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15207.x     Document Type: Article

References (37)

1. 2+ and cyclic AMP signalling systems in smooth muscle. Cell. Signal., 3, 371-385.
2. BARON, C.B., CUNNINGHAM, M., STRAUSS III, J.F. & COBORN, R.F. (1984). Pharmacomechanical coupling in smooth muscle may involve phosphatidylinositol metabolism. Proc. Nat. Acad. Sci. U.S.A., 81, 6899-6903.
3. BROWN, B.L., ALBANO, J.D.M., EKINS, R.P., SGHERZI, A.M. & TAMPION, W. (1971). A simple and sensitive saturation assay method lor measurement of adenosine-3′,5′-cyclic monophosphate. Biochem. J., 121, 561-562.
4. CHALLISS, R.A.J. & BOYLE, J.P. (1994). Modulation of agonist-stimulated phosphoinositide turnover in airways smooth muscle by cyclic nucleotide-dependent and independent mechanisms. In Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation, ed. Raeburn, D & Giembycz, M.A. pp. 309-327. Basel, Switzerland: Birkhauser.
5. CHALLISS, R.A.J., MISTRY, R., ADAMS, D. & NICHOLSON, C.D. (1995). Muscarinic cholinoceptor-stimulated inositol 1,4,5-trisphosphate generation and phasic contraction are inhibited by phosphodiesterase III/IV inhibition in airways smooth muscle. Br. J. Pharmacol., (in press).
6. DAYKIN, K., WIDDOP, S. & HALL, I.P. (1993). Control of histamine induced inositol phospholipid hydrolysis in cultured human tracheal smooth muscle cells. Eur. J. Pharmacol., 246, 135-140.
7. DE LANEROLLE, P. & PAUL, R.J. (1991). Myosin phosphorylation/ dephosphorylation and regulation of airway smooth muscle. Am. J. Physiol., 291, L1-14.
8. FELBEL, J., TROCKUR, B., ECKER, T., LANDGRAF, W. & HOFMANN, F. (1988). Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea. J. Biol. Chem., 263, 16764-16771.
9. GRUNSTEIN, M.M., SCHRAMM, C.M. & CHUANG, S.S. (1994). Inhibition of inositol 1,4,5-trisphosphate receptor binding by activation of the cAMP/protein kinase A signalling pathway in rabbit airway smooth muscle. Am. J. Respir. Crit. Care Med., 149, A1079.
10. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem., 260, 3440-3450.
11. HALL, I.P., DONALDSON, J. & HILL, S.J. (1989). Inhibition of histamine-stimulated inositol phospholipid hydrolysis by agents which increase cyclic AMP levels in bovine tracheal smooth muscle. Br. J. Pharmacol., 97, 603-613.
12. HALL, I.P. & HILL, S.J. (1988). β-Adrenoceptor stimulation inhibits histamine-stimulated inositol phospholipid hydrolysis in bovine tracheal smooth muscle. Br. J. Pharmacol., 95, 1204-1212.
13. HASHIMOTO, T., HIRATA, M. & ITO, Y. (1985). A role for inositol 1,4,5 trisphosphate in the initiation of agonist-induced contractions of dog tracheal smooth muscle. Br. J. Pharmacol., 86, 191-199.
14. JENNE, J.W., SHAUGHNESSY, T.K., DRUZ, W.S., MANFREDI, C.J. & VESTAL, R.E. (1987). In vivo functional antagonism between isoproterenol and bronchoconstrictants in the dog. J. Appl. Physiol., 63, 812-819.
15. JONKS, C.A., MADISON, J.M., TOM-MOY, M. & BROWN, J.K. (1987). Muscarinic cholinergic inhibition of adenylate cyclase in airway smooth muscle. Am. J. Physiol., 253, C97-C104.
16. KAJITA, J. & YAMAGUCHI, H. (1993). Calcium mobilization by muscarinic cholinergic stimulation in bovine single airway smooth muscle. Am. J. Physiol., 264, L496-L503.
17. MADISON, J.M. & BROWN, J.K. (1988). Differential inhibitory effects of forskolin, isoproterenol, and dibutyryl cyclic adenosine monophosphate on phosphoinositide hydrolysis in canine tracheal smooth muscle. J. Clin. Invest., 82, 1462-1465.
18. MEURS, H., ROFFEL, A.F., POSTEMA, J.B., TIMMERMANS, A., ELZINGA, C.R.S., KAUFFMAN, H.F. & ZAAGSMA, J. (1988). Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists. Eur. J. Pharmacol., 156, 271-274.
19. MEURS, H., TIMMERMANS, A., VAN AMSTERDAM, R.G.M., BROUWER, F., KAUFFMAN, H.F. & ZAAGSMA, J. (1989). Muscarinic receptors in human airway smooth muscle are coupled to phosphoinositide metabolism. Eur. J. Pharmacol., 164, 369-371.
20. MEURS, H., ROFFEL, A.F., ELZINGA, C.R.S., BOER, R.E.P.D.E. & ZAAGSMA, J. (1993). Muscarinic receptor-mediated inhibition of adenylyl cyclase and its role in the functional antagonism of isoprenaline in airway smooth muscle. Br. J. Pharmacol. 108, 208P.
21. MURRAY, R.K. & KOTLIKOFF, M.I. (1991). Receptor-activated calcium influx in human airway smooth muscle cells. J. Physiol., 435, 123-144.
22. OFFER, G.J., CHILVERS, E.R. & NAHORSKI, S.R. (1991). β-Adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle. Eur. J. Pharmacol., 207, 243-248.
23. 2+ and contraction induced by various stimulants and relaxants in canine tracheal smooth muscle. Pflügers Arch., 416, 351-359.
24. ROFFEL, A.F., MEURS, H., ELZINGA, C.R.S. & ZAAGSMA, J. (1990). Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle. Br. J. Pharmacol., 99, 293-296.
25. RUSSELL, J.A. (1984). Differential inhibitory effects of isoproterenol on contractions of canine airways. J. Appl. Physiol., 57, 801-807.
26. SIM, S.S., KIM, J.W. & RHEE, S.G. (1990). Regulation of D-myoinositol 1,4,5 trisphosphate 3-kinase by cAMP-dependent protein kinase and protein kinase C. J. Biol. Chem., 265, 10367-10372.
27. 2+ uptake by highly purified sarcolemmal vesicles of vascular smooth muscle. Biochem. Biophys. Acta, 773, 83-90.
28. TAKUWA, Y., TAKUWA, N. & RASMUSSEN, H. (1988). The effects of isoproterenol on intracellular calcium concentration. J. Biol. Chem., 263, 762-768.
29. 2+ is a primary determinant for myosine phosphorylation in smooth muscle cells. J. Biol. Chem., 264, 6207-6213.
30. TWORT, C.H.C. & VAN BREEMEN, C. (1989). Human airway smooth muscle in cell culture: Control of the intracellular calcium store. Pulm. Pharmacol., 2, 45-53.
31. VAN AMSTERDAM, R.G.M., MEURS, H., BROUWER, F., POSTEMA, J.B., TIMMERMANS, A. & ZAAGSMA, J. (1989). Role of phosphoinositide metabolism in functional antagonism of airway smooth muscle contraction by β-adrenoceptor agonists. Eur. J. Pharmacol., 172, 175-183.
32. VAN AMSTERDAM, R.G.M., MEURS, H., TEN BERGE, R.E.J., VENINGA, N.C.M., BROUWBR, F. & ZAAGSMA, J. (1990). Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by β-adrenoceptor agonists. Am. Rev. Respir. Dis., 142, 1124-1128.
33. VELEMA, J., NOORDMAN, P.C. & ZAAGSMA, J. (1983). Comparison of cyclic AMP-dependent phosphorylation of sarcolemma and sarcoplasmic reticulum from rat cardiac ventricle muscle. Int. J. Biochem., 15, 675-684.
34. 2+ release II. Effect of cAMP-dependent protein kinase. Am. J. Physiol., 258, C1086-C1091.
35. i in single airway smooth muscle cells. Am. J. Physiol., 268, C771-C779.
36. YANG, C.M., CHOU, S.-P. & SUNG, T.-C. (1991). Muscarinic receptor subtypes coupled to generation of different second messengers in isolated trachea smooth muscle cells. Br. J. Pharmacol., 104, 613-618.
37. ZHOU, H-L., NEWSHOLME, S.J. & TORPHY, T.J. (1992). Agonist-related differences in the relationship between cAMP content and protein kinase activity in canine trachealis. J. Pharmacol. Exp. Ther., 261, 1260-1267.