Use of transgenic mice in lipoprotein metabolism and atherosclerosis research

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 57, Issue 4-5, 1997, Pages 463-466

  Havekes, L M ^a   Van Vlijmen, B J M ^a   Jong, M C ^a   Van Dijk, K W ^a   Hofker, M H ^b  

^a TNO   (Netherlands)

^b Department of Human Genetics ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN C1; APOLIPOPROTEIN E; VERY LOW DENSITY LIPOPROTEIN;

AGE; ANIMAL MODEL; ANIMAL TISSUE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; DIET; FEMALE; GENDER; LIPID BLOOD LEVEL; LIPOPROTEIN METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0030734942     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-3278(97)90429-4     Document Type: Conference Paper

References (6)

1. Van den Maagdenberg A. M., J. M., Hofker M. H., Krimpenfort P. J. A., et al. Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia. J Biol Chem 1993; 268: 10540-10545.
2. . Van Vlijmen B., Van den Maagdenberg A. M. J. M., Gijbels M. J. J., et al. Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice. J Clin Invest 1994; 93: 1403-1410.
3. Groot P. H. E., van Vlijmen B. J. M., Benson G. M., et al. Quantitative assessment of aortic atherosclerosis in apoE3Leiden transgenic mice and its relationship to serum cholesterol exposure. Arterioscler Thromb Vasc Biol 1996; 16: 926-933.
4. Van Vlijmen B. J. M., van't Hof H. B., Mol M. J. T. M., et al. Modulation of very low density lipoprotein production and clearance contributes to age and gender dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice. J Clin Invest 1996; 97: 1184-1192.
5. Van Ree J. H., Hofker M. H., van den Broek W. J. A. A., et al. Increased response to cholesterol feeding in apolipoprotein Cl-deficient mice. Biochem J 1995; 305: 905-911.
6. Jong M. C., Dahlmans V. E. H., van Gorp P. J. J., et al. Both lipolysis and hepatic uptake of very low density lipoproteins are impaired in transgenic mice co-expressing human apolipoprotein E*3Leiden and human apolipoprotein C1. Arterioscler Thromb Vasc Biol 1996; 16: 934-940.