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Volumn 4, Issue 11, 1997, Pages 1237-1245

Adenovirus-mediated transfer of a functional GAD gene into nerve cells: Potential for the treatment of neurological diseases

Author keywords

Adenoviral vector; Brain cells; Epilepsy; GABA; GAD; Gene therapy

Indexed keywords

4 AMINOBUTYRIC ACID; NEUROTRANSMITTER; VIRUS VECTOR;

EID: 0030733145     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300521     Document Type: Article
Times cited : (24)

References (53)
  • 1
    • 0024283304 scopus 로고
    • Transgenic animals
    • Jaenisch R. Transgenic animals. Science 1988; 240: 1468-1474.
    • (1988) Science , vol.240 , pp. 1468-1474
    • Jaenisch, R.1
  • 3
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996; 272: 263267.
    • (1996) Science , vol.272 , pp. 263267
    • Naldini, L.1
  • 4
    • 0027512404 scopus 로고
    • Gene delivery into the brain using virus vectors
    • Breakefield XO. Gene delivery into the brain using virus vectors. Nat Genet 1993; 3: 187-189.
    • (1993) Nat Genet , vol.3 , pp. 187-189
    • Breakefield, X.O.1
  • 5
    • 0027158244 scopus 로고
    • Gene therapy for disorders of the nervous system
    • Friedmann T, Hyder AJ. Gene therapy for disorders of the nervous system. Tibtech 1993; 11: 192-197.
    • (1993) Tibtech , vol.11 , pp. 192-197
    • Friedmann, T.1    Hyder, A.J.2
  • 7
    • 0027525494 scopus 로고
    • Gene therapy for neurological disease
    • Suhr SR, Gage FH. Gene therapy for neurological disease. Arch Neurol 1993; 50: 1252-1268.
    • (1993) Arch Neurol , vol.50 , pp. 1252-1268
    • Suhr, S.R.1    Gage, F.H.2
  • 8
    • 0030296554 scopus 로고    scopus 로고
    • Immune responses to adenovirus vectors in the nervous system
    • Wood MJ et al. Immune responses to adenovirus vectors in the nervous system. Trends Neurosci 1996; 19: 497-501.
    • (1996) Trends Neurosci , vol.19 , pp. 497-501
    • Wood, M.J.1
  • 9
    • 0029760296 scopus 로고    scopus 로고
    • Role of T cells in inflammation caused by adenovirus vectors in the brain
    • Byrnes AP, Wood MJ, Charlton HM. Role of T cells in inflammation caused by adenovirus vectors in the brain. Gene Therapy 1996; 3: 644-651.
    • (1996) Gene Therapy , vol.3 , pp. 644-651
    • Byrnes, A.P.1    Wood, M.J.2    Charlton, H.M.3
  • 10
    • 0027408530 scopus 로고
    • Transfer of a foreign gene into the brain using adenovirus vectors
    • Akli S et al. Transfer of a foreign gene into the brain using adenovirus vectors. Nat Genet 1993; 3: 224-228.
    • (1993) Nat Genet , vol.3 , pp. 224-228
    • Akli, S.1
  • 11
    • 0027477148 scopus 로고
    • Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors
    • Bajocchi G, Feldman SH, Crystal RG, Mastrangeli A. Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nat Genet 1993; 3: 229-234.
    • (1993) Nat Genet , vol.3 , pp. 229-234
    • Bajocchi, G.1    Feldman, S.H.2    Crystal, R.G.3    Mastrangeli, A.4
  • 12
    • 0027522920 scopus 로고
    • A model system for in vivo gene transfer into the central nervous system using an adenoviral vector
    • Davidson BL et al. A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nat Genet 1993; 3: 219-223.
    • (1993) Nat Genet , vol.3 , pp. 219-223
    • Davidson, B.L.1
  • 13
    • 0000185612 scopus 로고
    • Adenovirus as a potent vector for gene transfer in neurons and glia in the brain
    • Le Gal La Salle G et al. Adenovirus as a potent vector for gene transfer in neurons and glia in the brain. Science 1993; 235: 986-988.
    • (1993) Science , vol.235 , pp. 986-988
    • Le Gal La Salle, G.1
  • 14
    • 0027432367 scopus 로고
    • Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells
    • Caillaud C et al. Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells. Euro J Neurosci 1993; 5: 1287-1291.
    • (1993) Euro J Neurosci , vol.5 , pp. 1287-1291
    • Caillaud, C.1
  • 15
    • 0027395911 scopus 로고
    • Regulation of γ-aminobutyric acid synthesis in the brain
    • Martin DL, Rimvall K. Regulation of γ-aminobutyric acid synthesis in the brain. J Neurochem 1993; 60: 395-407.
    • (1993) J Neurochem , vol.60 , pp. 395-407
    • Martin, D.L.1    Rimvall, K.2
  • 17
    • 0030041347 scopus 로고    scopus 로고
    • The clinical significance of an autoimmune response against glutamic acid decarboxylase
    • Ellis TM, Atkinson MA. The clinical significance of an autoimmune response against glutamic acid decarboxylase. Nature Med 1996; 2: 148-153.
    • (1996) Nature Med , vol.2 , pp. 148-153
    • Ellis, T.M.1    Atkinson, M.A.2
  • 18
    • 0028179659 scopus 로고
    • Cellular and molecular basis of epilepsy
    • McNamara J. Cellular and molecular basis of epilepsy. J Neurosci 1994; 14: 3413-3425.
    • (1994) J Neurosci , vol.14 , pp. 3413-3425
    • McNamara, J.1
  • 19
    • 0026547373 scopus 로고
    • GABA and epilepsy: Their complex relationship and the evolution of our understanding
    • Snodgrass SR. GABA and epilepsy: their complex relationship and the evolution of our understanding. J Child Neural 1992; 7: 77-86.
    • (1992) J Child Neural , vol.7 , pp. 77-86
    • Snodgrass, S.R.1
  • 20
    • 0025087703 scopus 로고
    • Long-term increase of glutamate decarboxylase mRNA in a rat model of temporal lobe epilepsy
    • Feldblum S, Ackermann RF, Tobin AJ. Long-term increase of glutamate decarboxylase mRNA in a rat model of temporal lobe epilepsy. Neuron 1990; 5: 361-371.
    • (1990) Neuron , vol.5 , pp. 361-371
    • Feldblum, S.1    Ackermann, R.F.2    Tobin, A.J.3
  • 21
    • 0025117514 scopus 로고
    • GABAergic neurons are spared after intrahippocampal kainate in the rat
    • Davenport CJ, Brown WJ, Babb TL. GABAergic neurons are spared after intrahippocampal kainate in the rat. Epilepsy Res 1990; 5: 28-42.
    • (1990) Epilepsy Res , vol.5 , pp. 28-42
    • Davenport, C.J.1    Brown, W.J.2    Babb, T.L.3
  • 22
    • 0024322622 scopus 로고
    • Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus
    • Babb TL, Pretorias JK, Kupfer WR, Crandall PH. Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J Neurosci 1989; 9: 2562-2574.
    • (1989) J Neurosci , vol.9 , pp. 2562-2574
    • Babb, T.L.1    Pretorias, J.K.2    Kupfer, W.R.3    Crandall, P.H.4
  • 23
    • 0028840599 scopus 로고
    • Hippocampal granule cells express glutamic acid decarboxylase-67 after limbic seizures in the rat
    • Schwarzer C, Sperk G. Hippocampal granule cells express glutamic acid decarboxylase-67 after limbic seizures in the rat. J Neurosci 1995; 69: 705-709.
    • (1995) J Neurosci , vol.69 , pp. 705-709
    • Schwarzer, C.1    Sperk, G.2
  • 24
    • 0026577196 scopus 로고
    • Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene
    • Bu DF et al. Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene. Proc Natl Acad Sci USA 1992; 89: 2115-2119.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2115-2119
    • Bu, D.F.1
  • 25
    • 0028287440 scopus 로고
    • Adenoviral vectors as functional retrograde neuronal tracers
    • Ridoux V et al. Adenoviral vectors as functional retrograde neuronal tracers. Brain Res 1994; 648: 171-175.
    • (1994) Brain Res , vol.648 , pp. 171-175
    • Ridoux, V.1
  • 26
    • 0029123286 scopus 로고
    • CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: Complete rescue of axotomized cholinergic neurons after transplantation into the septum
    • Martinez-Serrano A et al. CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after transplantation into the septum. J Neurosci 1995; 15: 5668-5680.
    • (1995) J Neurosci , vol.15 , pp. 5668-5680
    • Martinez-Serrano, A.1
  • 27
    • 0029982488 scopus 로고    scopus 로고
    • Astrocytes infected with replication-defective adenovirus containing a secreted form of CNTF or NT3 show enhanced support of neuronal populations in vitro
    • Smith GM et al. Astrocytes infected with replication-defective adenovirus containing a secreted form of CNTF or NT3 show enhanced support of neuronal populations in vitro. Exp Neurol 1996; 139: 156-166.
    • (1996) Exp Neurol , vol.139 , pp. 156-166
    • Smith, G.M.1
  • 28
    • 0029122388 scopus 로고
    • Construction and characterization of adenoviral vector expressing biologically active brain-derived neurotrophic factor
    • Kojima H et al. Construction and characterization of adenoviral vector expressing biologically active brain-derived neurotrophic factor. Biochem Biophys Res Commun 1995; 212: 712-717.
    • (1995) Biochem Biophys Res Commun , vol.212 , pp. 712-717
    • Kojima, H.1
  • 29
    • 0028202066 scopus 로고
    • Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
    • Chen SH et al. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc Natl Acad Sci USA 1994; 91: 3054-3057.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3054-3057
    • Chen, S.H.1
  • 30
    • 0029043098 scopus 로고
    • Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats
    • Badie B et al. Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats. Neurol Res 1995; 17: 209-216.
    • (1995) Neurol Res , vol.17 , pp. 209-216
    • Badie, B.1
  • 31
    • 0029101080 scopus 로고
    • Adenovirus-mediated gene therapy for experimental spinal cord tumors: Tumoricidal efficacy and functional outcome
    • Colak A et al. Adenovirus-mediated gene therapy for experimental spinal cord tumors: tumoricidal efficacy and functional outcome. Brain Res 1995; 691: 76-82.
    • (1995) Brain Res , vol.691 , pp. 76-82
    • Colak, A.1
  • 32
    • 0028826147 scopus 로고
    • Delivery of herpes virus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption
    • Nilaver G et al. Delivery of herpes virus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption. Proc Natl Acad Sci USA 1995; 92: 9829-9833.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9829-9833
    • Nilaver, G.1
  • 33
    • 0027973509 scopus 로고
    • Adenovirus-mediated gene therapy of experimental gliomas
    • Perez-Cruet MJ et al Adenovirus-mediated gene therapy of experimental gliomas. J Neurosci Res 1994; 39: 506-511.
    • (1994) J Neurosci Res , vol.39 , pp. 506-511
    • Perez-Cruet, M.J.1
  • 34
    • 0029671441 scopus 로고    scopus 로고
    • Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle
    • Askanas J et al. Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle. Proc Natl Acad Sci USA 1996; 93: 1314-1319.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1314-1319
    • Askanas, J.1
  • 35
    • 0028606905 scopus 로고
    • Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease
    • Horellou P et al. Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease. Neuroreport 1994; 6: 49-53.
    • (1994) Neuroreport , vol.6 , pp. 49-53
    • Horellou, P.1
  • 36
    • 0027163719 scopus 로고
    • Rat-1 fibroblasts engineered with GAD65 and GAD67 cDNAs in retroviral vectors produce and release GABA
    • Ruppert C et al. Rat-1 fibroblasts engineered with GAD65 and GAD67 cDNAs in retroviral vectors produce and release GABA. J Neurochem 1993; 61: 768-771.
    • (1993) J Neurochem , vol.61 , pp. 768-771
    • Ruppert, C.1
  • 37
    • 0027769488 scopus 로고
    • Immortalized GABAergic cell lines derived from rat striarum using a temperature sensitive allele of the SV40 large T antigen
    • Giordano M et al. Immortalized GABAergic cell lines derived from rat striarum using a temperature sensitive allele of the SV40 large T antigen. Exp Neurol 1993; 124: 395-400.
    • (1993) Exp Neurol , vol.124 , pp. 395-400
    • Giordano, M.1
  • 38
    • 0027232980 scopus 로고
    • Establishment of a stable glutamate decarboxylase (GAD) expressing cell-line by transfection
    • Zhou FC, Cheng C, Bledsoe S. Establishment of a stable glutamate decarboxylase (GAD) expressing cell-line by transfection. Cell Transplantation 1993; 2: 193-205.
    • (1993) Cell Transplantation , vol.2 , pp. 193-205
    • Zhou, F.C.1    Cheng, C.2    Bledsoe, S.3
  • 39
    • 0029240687 scopus 로고
    • Adenovirus-mediated gene transfer in organotypic brain slices
    • Ridoux V et al. Adenovirus-mediated gene transfer in organotypic brain slices. Neurobiol Dis 1995; 2: 49-54.
    • (1995) Neurobiol Dis , vol.2 , pp. 49-54
    • Ridoux, V.1
  • 40
    • 0028346175 scopus 로고
    • The use of adenovirus vectors for intracerebral grafting of transfected nervous cells
    • Ridoux V et al. The use of adenovirus vectors for intracerebral grafting of transfected nervous cells. Neuroreport 1994; 5: 801804.
    • (1994) Neuroreport , vol.5 , pp. 801804
    • Ridoux, V.1
  • 41
    • 0030563195 scopus 로고    scopus 로고
    • Adenoviruses as gene-deliverv vehicles
    • Wilson JM. Adenoviruses as gene-deliverv vehicles. New Engl J Med 1996; 334: 1185-1187.
    • (1996) New Engl J Med , vol.334 , pp. 1185-1187
    • Wilson, J.M.1
  • 43
    • 0023088674 scopus 로고
    • Molecular cloning, expression and in situ hybridization of rat brain glutamic acid decarboxylase messenger RNA
    • Julien JF et al. Molecular cloning, expression and in situ hybridization of rat brain glutamic acid decarboxylase messenger RNA. Neurosci Lett 1987; 73: 173-180.
    • (1987) Neurosci Lett , vol.73 , pp. 173-180
    • Julien, J.F.1
  • 44
    • 0023392945 scopus 로고
    • High-efficiency transformation of mammalian cells by plasmid DNA
    • Chen C, Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 1987; 7: 2745-2752.
    • (1987) Mol Cell Biol , vol.7 , pp. 2745-2752
    • Chen, C.1    Okayama, H.2
  • 45
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus 5
    • Graham FL, Smiley J, Russel WC, Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus 5. J Gen Virol 1977; 36: 59-72.
    • (1977) J Gen Virol , vol.36 , pp. 59-72
    • Graham, F.L.1    Smiley, J.2    Russel, W.C.3    Nairn, R.4
  • 47
    • 0020685169 scopus 로고
    • Palindromic adenovirus type 5-simian virus 40 hybrid
    • Gluzman Y, Van Doren K. Palindromic adenovirus type 5-simian virus 40 hybrid. J Virol 1983; 45: 91-103.
    • (1983) J Virol , vol.45 , pp. 91-103
    • Gluzman, Y.1    Van Doren, K.2
  • 48
    • 0028082502 scopus 로고
    • In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus
    • Bessereau JL et al. In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus. Proc Natl Acad Sci USA 1994; 91: 1304-1308.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1304-1308
    • Bessereau, J.L.1
  • 49
    • 0014329310 scopus 로고
    • The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12
    • Maizel JV, White DO, Scharff MD. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology 1968; 36: 115-125.
    • (1968) Virology , vol.36 , pp. 115-125
    • Maizel, J.V.1    White, D.O.2    Scharff, M.D.3
  • 50
    • 0014748494 scopus 로고
    • Early events in the interaction of adenoviruses with HeLa cells. I. Penetration of type 5 and intracellular release of the DNA genome
    • Chardonnet Y, Dales S. Early events in the interaction of adenoviruses with HeLa cells. I. Penetration of type 5 and intracellular release of the DNA genome. Virology 1970; 40: 462-477.
    • (1970) Virology , vol.40 , pp. 462-477
    • Chardonnet, Y.1    Dales, S.2
  • 51
    • 0018322590 scopus 로고
    • Long-term culture of dissociated sympathetic neurons
    • Hawrot E, Patterson PH. Long-term culture of dissociated sympathetic neurons. Meth Enzymol 1979; 58: 574-584.
    • (1979) Meth Enzymol , vol.58 , pp. 574-584
    • Hawrot, E.1    Patterson, P.H.2
  • 52
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L, Buchs PA, Muller D. A simple method for organotypic cultures of nervous tissue. J Neurosci Meth 1991; 37: 173-182.
    • (1991) J Neurosci Meth , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3


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