-
1
-
-
0020010617
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons. Examinations of the mechanism of toxicity
-
A. Poland and J.C. Knutson, 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons. Examinations of the mechanism of toxicity, Annu. Rev. Pharmacol. Toxicol., 22 (1982) 517-554.
-
(1982)
Annu. Rev. Pharmacol. Toxicol.
, vol.22
, pp. 517-554
-
-
Poland, A.1
Knutson, J.C.2
-
2
-
-
0000539634
-
Mechanism of action and structure-activity relationships for the chlorinated dibenzo-p-dioxins and related compounds
-
R.D. Kimbrough and A.A. Jensen (Eds.), Elsevier-North Holland, Amsterdam
-
J.A. Goldstein and S. Safe, Mechanism of action and structure-activity relationships for the chlorinated dibenzo-p-dioxins and related compounds, in: R.D. Kimbrough and A.A. Jensen (Eds.), Halogenated Biphenyls, Naphthalenes, Dibenzodioxins and Related Compounds, Elsevier-North Holland, Amsterdam, 1989, pp. 239-293.
-
(1989)
Halogenated Biphenyls, Naphthalenes, Dibenzodioxins and Related Compounds
, pp. 239-293
-
-
Goldstein, J.A.1
Safe, S.2
-
3
-
-
0027521742
-
Mechanistic aspects of dioxin action
-
J.P. Whitlock, Jr. Mechanistic aspects of dioxin action, Chem. Res. Toxicol., 6 (1993) 754-763.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 754-763
-
-
Whitlock J.P., Jr.1
-
4
-
-
0026749010
-
cDNA cloning and structure of the putative Ah receptor
-
M. Ema, K. Sogawa, N. Watanabe, Y. Chujoh, N. Matsushita, O. Gotoh, Y. Funae and Y. Fujii-Kuriyama, cDNA cloning and structure of the putative Ah receptor, Biochem. Biophys. Res. Commun., 184 (1992) 246-253.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.184
, pp. 246-253
-
-
Ema, M.1
Sogawa, K.2
Watanabe, N.3
Chujoh, Y.4
Matsushita, N.5
Gotoh, O.6
Funae, Y.7
Fujii-Kuriyama, Y.8
-
5
-
-
0022570025
-
Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P450c gene
-
A. Fujisawa-Sehara, K. Sogawa, C. Nishi and Y. Fujii-Kuriyama, Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P450c gene, Nucl. Acids Res., 14 (1986) 1465-1477.
-
(1986)
Nucl. Acids Res.
, vol.14
, pp. 1465-1477
-
-
Fujisawa-Sehara, A.1
Sogawa, K.2
Nishi, C.3
Fujii-Kuriyama, Y.4
-
6
-
-
0024472675
-
1-450 gene expression in mouse hepatoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
1-450 gene expression in mouse hepatoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin, Drug Metab. Rev., 20 (1989) 839-846.
-
(1989)
Drug Metab. Rev.
, vol.20
, pp. 839-846
-
-
Whitlock J.P., Jr.1
Denison, M.S.2
Durrin, L.K.3
Fisher, J.M.4
Galeazzi, D.R.5
Jones, P.B.C.6
-
7
-
-
0021289379
-
1-450 gene transcription by 2,3,7,8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells
-
1-450 gene transcription by 2,3,7,8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells, J. Biol. Chem., 259 (1984) 5400-5402.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 5400-5402
-
-
Israel, D.I.1
Whitlock J.P., Jr.2
-
9
-
-
0026569524
-
Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell line 1c1c7
-
G.H. Perdew, Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell line 1c1c7, Biochem. Biophys. Res. Commun., 182 (1992) 55-62.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.182
, pp. 55-62
-
-
Perdew, G.H.1
-
10
-
-
0023741595
-
Association of the dioxin receptor with the mr 90 000 heat shock protein: A structural kinship with the glucocorticoid receptor
-
M. Denis, S. Cuthill, A.C. Wilkstrom, L. Poellinger and J. Gustafsson, Association of the dioxin receptor with the mr 90 000 heat shock protein: a structural kinship with the glucocorticoid receptor, Biochem. Biophys. Res. Commun., 155 (1989) 801-807.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.155
, pp. 801-807
-
-
Denis, M.1
Cuthill, S.2
Wilkstrom, A.C.3
Poellinger, L.4
Gustafsson, J.5
-
11
-
-
0027970550
-
Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex
-
H. Chen and G.H. Perdew, Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex, J. Biol. Chem., 269 (1994) 27554-27558.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27554-27558
-
-
Chen, H.1
Perdew, G.H.2
-
12
-
-
0027135268
-
Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells
-
G.H. Perdew, N. Hord, C.E. Hollenback and M.J. Welsh, Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells, Exp. Cell Res., 209 (1993) 350-356.
-
(1993)
Exp. Cell Res.
, vol.209
, pp. 350-356
-
-
Perdew, G.H.1
Hord, N.2
Hollenback, C.E.3
Welsh, M.J.4
-
13
-
-
0026631538
-
Dual roles of the 90 kDa heat shock protein Hsp 90 in modulating functional activities of the dioxin receptor
-
I. Pongratz, G.G.F. Mason and L. Poellinger, Dual roles of the 90 kDa heat shock protein Hsp 90 in modulating functional activities of the dioxin receptor, J. Biol. Chem., 267 (1992) 13728-13734.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13728-13734
-
-
Pongratz, I.1
Mason, G.G.F.2
Poellinger, L.3
-
14
-
-
0025906014
-
Cloning of a factor required for activity of the Ah (dioxin) receptor
-
E.C. Hoffman, H. Reyes, F. Chu, F. Sander, L.H. Conley, B.A. Brooks and O. Hankinson, Cloning of a factor required for activity of the Ah (dioxin) receptor, Science, 252 (1991) 954-958.
-
(1991)
Science
, vol.252
, pp. 954-958
-
-
Hoffman, E.C.1
Reyes, H.2
Chu, F.3
Sander, F.4
Conley, L.H.5
Brooks, B.A.6
Hankinson, O.7
-
15
-
-
0025201536
-
Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric
-
C.J. Elferink, T.A. Gasiewicz and J.P. Whitlock, Jr., Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric, J. Biol. Chem., 265 (1990) 20708-20712.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20708-20712
-
-
Elferink, C.J.1
Gasiewicz, T.A.2
Whitlock J.P., Jr.3
-
16
-
-
0025752367
-
Characterization of multiple forms of the Ah receptor: Recognition of a dioxin-responsive enhancer involves heteromer formation
-
T.A. Gasiewicz, C.J. Elferink and E.C. Henry, Characterization of multiple forms of the Ah receptor: recognition of a dioxin-responsive enhancer involves heteromer formation, Biochemistry, 30 (1991) 2909-2916.
-
(1991)
Biochemistry
, vol.30
, pp. 2909-2916
-
-
Gasiewicz, T.A.1
Elferink, C.J.2
Henry, E.C.3
-
17
-
-
0027403810
-
Ligand-dependent recruitment of the arnt coregulator determines DNA recognition by the dioxin receptor
-
M. Whitelaw, I. Pongratz, A. Wilhelmsson, J.A. Gustafsson and L. Poellinger, Ligand-dependent recruitment of the arnt coregulator determines DNA recognition by the dioxin receptor, Mol. Cell. Biol., 13 (1993) 2504-2514.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2504-2514
-
-
Whitelaw, M.1
Pongratz, I.2
Wilhelmsson, A.3
Gustafsson, J.A.4
Poellinger, L.5
-
18
-
-
0024210678
-
The DNA recognition site for the dioxin-Ah receptor complex
-
M.S. Denison, J.M. Fisher and J.P. Whitlock, Jr. The DNA recognition site for the dioxin-Ah receptor complex, J. Biol. Chem., 263 (1988) 17221-17224.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 17221-17224
-
-
Denison, M.S.1
Fisher, J.M.2
Whitlock J.P., Jr.3
-
19
-
-
0025806510
-
Transcriptional regulation of the rat NAD(P)H:Quinone reductase gene
-
L.V. Favreau and C.B. Pickett, Transcriptional regulation of the rat NAD(P)H:quinone reductase gene, J. Biol. Chem., 266 (1991) 4556-4561.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 4556-4561
-
-
Favreau, L.V.1
Pickett, C.B.2
-
20
-
-
0020320502
-
Regulatory gene product of the Ah locus: Characterization of receptor mutants among mouse hepatoma clones
-
C. Legraverend, R.R. Hannah, H.J. Eisen, I.S. Owens, D.W. Nebert and O. Hankinson, Regulatory gene product of the Ah locus: characterization of receptor mutants among mouse hepatoma clones, J. Biol. Chem., 257 (1982) 6402-6407.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 6402-6407
-
-
Legraverend, C.1
Hannah, R.R.2
Eisen, H.J.3
Owens, I.S.4
Nebert, D.W.5
Hankinson, O.6
-
21
-
-
0024997241
-
Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene: Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants
-
T.H. Rushmore and C.B. Pickett, Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene: characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants, J. Biol. Chem., 265 (1990) 14648-14653.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 14648-14653
-
-
Rushmore, T.H.1
Pickett, C.B.2
-
22
-
-
0023871977
-
Glutathione S-transferase Ya subunit gene: Identification of regulatory elements required for basal level and inducible expression
-
C.A. Telakowski-Hopkins, R.G. King and C.B. Pickett, Glutathione S-transferase Ya subunit gene: identification of regulatory elements required for basal level and inducible expression, Proc. Natl. Acad. Sci. USA, 85 (1988) 1000-1004.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1000-1004
-
-
Telakowski-Hopkins, C.A.1
King, R.G.2
Pickett, C.B.3
-
23
-
-
0024207289
-
Physicochemical characterization of the nuclear form of Ah receptor from mouse hepatoma cells exposed in culture to 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
R.D. Prokipcak and A.B. Okey, Physicochemical characterization of the nuclear form of Ah receptor from mouse hepatoma cells exposed in culture to 2,3,7,8-tetrachlorodibenzo-p-dioxin, Arch. Biochem. Biophys., 267 (1988) 811-828.
-
(1988)
Arch. Biochem. Biophys.
, vol.267
, pp. 811-828
-
-
Prokipcak, R.D.1
Okey, A.B.2
-
25
-
-
0025302841
-
Human estrogen receptor multiple protein-DNA complexes
-
M. Brown and P.A. Sharp, Human estrogen receptor multiple protein-DNA complexes, J. Biol. Chem., 265 (1990) 11238-11243.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 11238-11243
-
-
Brown, M.1
Sharp, P.A.2
-
26
-
-
0026406784
-
Uterine estrogen receptor-DNA complexes: Effects of different ERE sequences, ligands and receptor forms
-
S.W. Curtis and K.S. Korach, Uterine estrogen receptor-DNA complexes: effects of different ERE sequences, ligands and receptor forms, Mol. Endocrinel., 5 (1991) 959-966.
-
(1991)
Mol. Endocrinel.
, vol.5
, pp. 959-966
-
-
Curtis, S.W.1
Korach, K.S.2
-
27
-
-
0024293495
-
Identification of a novel lymphoid specific octomer binding protein (OTF-2B) by proteolytic clipping band shift assay (PCBA)
-
E. Schreiber, P. Matthias, M.M. Muller and W. Schaffner, Identification of a novel lymphoid specific octomer binding protein (OTF-2B) by proteolytic clipping band shift assay (PCBA), EMBO J., 7 (1988) 4221-4229.
-
(1988)
EMBO J.
, vol.7
, pp. 4221-4229
-
-
Schreiber, E.1
Matthias, P.2
Muller, M.M.3
Schaffner, W.4
-
28
-
-
0024270618
-
Radioligand-dependent differences in the molecular properties of the mouse and rat hepatic aryl hydrocarbon receptor complexes
-
J. Piskorska-Pliszczynska and S. Safe, Radioligand-dependent differences in the molecular properties of the mouse and rat hepatic aryl hydrocarbon receptor complexes, Arch. Biochem. Biophys., 267 (1988) 372-383.
-
(1988)
Arch. Biochem. Biophys.
, vol.267
, pp. 372-383
-
-
Piskorska-Pliszczynska, J.1
Safe, S.2
-
29
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
M.M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72 (1976) 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
30
-
-
0020038220
-
Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene-, or mixed-type inducers to cytosolic Ah receptor
-
S. Bandiera, S. Safe and A.B. Okey, Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene-, or mixed-type inducers to cytosolic Ah receptor, Chem.-Biol. Interact., 39 (1982) 259-277.
-
(1982)
Chem.-Biol. Interact.
, vol.39
, pp. 259-277
-
-
Bandiera, S.1
Safe, S.2
Okey, A.B.3
-
32
-
-
0025969240
-
Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer
-
M.S. Denison and E.F. Yao, Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer, Arch. Biochem. Biophys., 284 (1991) 158-166.
-
(1991)
Arch. Biochem. Biophys.
, vol.284
, pp. 158-166
-
-
Denison, M.S.1
Yao, E.F.2
-
33
-
-
0026643609
-
DNA sequence determinants for binding of transformed Ah-receptor to a dioxin-responsive enhancer
-
E.F. Yao and M.S. Denison, DNA sequence determinants for binding of transformed Ah-receptor to a dioxin-responsive enhancer, Biochemistry, 31 (1992) 5060-5067.
-
(1992)
Biochemistry
, vol.31
, pp. 5060-5067
-
-
Yao, E.F.1
Denison, M.S.2
-
34
-
-
0026644794
-
Protein-DNA interactions at a dioxin-responsive enhancer - Mutational analysis of the DNA-binding site for the liganded Ah receptor
-
E.S. Shen and J.P. Whitlock, Protein-DNA interactions at a dioxin-responsive enhancer - mutational analysis of the DNA-binding site for the liganded Ah receptor, J. Biol. Chem., 267 (1992) 6815-6819.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 6815-6819
-
-
Shen, E.S.1
Whitlock, J.P.2
-
35
-
-
0026457123
-
Mechanism of action of aryl hydrocarbon receptor antagonists: Inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression
-
M. Merchant, V. Morrison, M. Santostefano and S. Safe, Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression, Arch. Biochem. Biophys., 298 (1992) 389-394.
-
(1992)
Arch. Biochem. Biophys.
, vol.298
, pp. 389-394
-
-
Merchant, M.1
Morrison, V.2
Santostefano, M.3
Safe, S.4
-
36
-
-
0027235615
-
Mechanism of action of α-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells
-
M. Merchant, V. Krishnan and S. Safe, Mechanism of action of α-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells, Toxicol. Appl. Pharmacol., 120 (1993) 179-185.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.120
, pp. 179-185
-
-
Merchant, M.1
Krishnan, V.2
Safe, S.3
-
37
-
-
0025836770
-
α-Naphthofiavone acts as an antagonist of 2,3,7,8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor
-
T.A. Gasiewicz and G. Rucci, α-Naphthofiavone acts as an antagonist of 2,3,7,8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor, Mol. Pharmacol., 40 (1991) 607-612.
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 607-612
-
-
Gasiewicz, T.A.1
Rucci, G.2
-
38
-
-
0027509084
-
α-Naphthoflavone-induced CYP1A1 gene expression and cytosolic Ah receptor transformation
-
M. Santostefano, M. Merchant, L. Arellano, V. Morrison, M.S. Denison and S. Safe, α-Naphthoflavone-induced CYP1A1 gene expression and cytosolic Ah receptor transformation, Mol. Pharmacol., 43 (1993) 200-206.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 200-206
-
-
Santostefano, M.1
Merchant, M.2
Arellano, L.3
Morrison, V.4
Denison, M.S.5
Safe, S.6
-
39
-
-
0025954669
-
Use of artificial intelligence in structure-affinity correlations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) receptor ligands
-
U. Rannug, M. Sjogren, A. Rannug, M. Gillner, R. Toftgard, J.A. Gustafsson, H. Rosenkranz and G. Klopman, Use of artificial intelligence in structure-affinity correlations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) receptor ligands, Carcinogenesis, 12 (1991) 2007-2015.
-
(1991)
Carcinogenesis
, vol.12
, pp. 2007-2015
-
-
Rannug, U.1
Sjogren, M.2
Rannug, A.3
Gillner, M.4
Toftgard, R.5
Gustafsson, J.A.6
Rosenkranz, H.7
Klopman, G.8
-
40
-
-
0022384065
-
Interactions of indoles with specific binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver
-
M. Gillner, J. Bergman, C. Cambillau, C. Fernström and J. Gustafsson, Interactions of indoles with specific binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, Mol. Pharmacol., 28 (1985) 357-363.
-
(1985)
Mol. Pharmacol.
, vol.28
, pp. 357-363
-
-
Gillner, M.1
Bergman, J.2
Cambillau, C.3
Fernström, C.4
Gustafsson, J.5
-
41
-
-
0024566306
-
Interactions of nitaecarpine alkaloids with specific binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver
-
M. Gillner, J. Bergman, C. Cambillau and J. Gustafsson, Interactions of nitaecarpine alkaloids with specific binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, Carcinogenesis, 10 (1989) 651-654.
-
(1989)
Carcinogenesis
, vol.10
, pp. 651-654
-
-
Gillner, M.1
Bergman, J.2
Cambillau, C.3
Gustafsson, J.4
-
42
-
-
0022969614
-
The cytosolic receptor binding affinities and AHH induction potencies of 29 polynuclear aromatic hydrocarbons
-
J. Piskorska-Pliszczynska, B. Keys, S. Safe and M.S. Newman, The cytosolic receptor binding affinities and AHH induction potencies of 29 polynuclear aromatic hydrocarbons, Toxicol. Lett., 34 (1986) 67-74.
-
(1986)
Toxicol. Lett.
, vol.34
, pp. 67-74
-
-
Piskorska-Pliszczynska, J.1
Keys, B.2
Safe, S.3
Newman, M.S.4
-
43
-
-
0020042665
-
The Ah regulatory gene product. Survey of nineteen polycyclic aromatic compounds' and fifteen benzo[a]pyrene metabolites' capacity to bind to the cytosolic receptor
-
S.W. Bigelow and D.W. Nebert, The Ah regulatory gene product. Survey of nineteen polycyclic aromatic compounds' and fifteen benzo[a]pyrene metabolites' capacity to bind to the cytosolic receptor, Toxicol. Lett., 10 (1982) 109-118.
-
(1982)
Toxicol. Lett.
, vol.10
, pp. 109-118
-
-
Bigelow, S.W.1
Nebert, D.W.2
-
44
-
-
0023616773
-
Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances
-
A. Rannug, U. Rannug, H.S. Rosenkranz, L. Winqvist, R. Westerholm, E. Agurell and A. Grafstrom, Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances, J. Biol. Chem., 262 (1987) 15422-15427.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 15422-15427
-
-
Rannug, A.1
Rannug, U.2
Rosenkranz, H.S.3
Winqvist, L.4
Westerholm, R.5
Agurell, E.6
Grafstrom, A.7
-
45
-
-
0026669389
-
Chelatable metal ions are not required for aryl hydrocarbon receptor transformation to a DNA binding form: Phenanthrolines are possible competitive antagonists of 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
M.J. Mahon and T.A. Gasiewicz, Chelatable metal ions are not required for aryl hydrocarbon receptor transformation to a DNA binding form: phenanthrolines are possible competitive antagonists of 2,3,7,8-tetrachlorodibenzo-p-dioxin, Arch. Biochem. Biophys., 297 (1992) 1-8.
-
(1992)
Arch. Biochem. Biophys.
, vol.297
, pp. 1-8
-
-
Mahon, M.J.1
Gasiewicz, T.A.2
-
46
-
-
0023845568
-
Binding characteristics of Ah receptors from rats and mice before and after separation from hepatic cytosols: 7-hydroxyellipticine as a competitive antagonist of cytochrome P450 induction
-
N. Fernandez, M. Roy and P. Lesca, Binding characteristics of Ah receptors from rats and mice before and after separation from hepatic cytosols: 7-hydroxyellipticine as a competitive antagonist of cytochrome P450 induction, Eur. J. Biochem., 172 (1988) 585-592.
-
(1988)
Eur. J. Biochem.
, vol.172
, pp. 585-592
-
-
Fernandez, N.1
Roy, M.2
Lesca, P.3
-
47
-
-
0018609570
-
Regulatory gene product of the Ah locus: Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation
-
A.B. Okey, G.P. Bondy, M.E. Mason, G.F. Kahl, H.J. Eisen, T.M. Guenthner and D.W. Nebert, Regulatory gene product of the Ah locus: characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation, J. Biol. Chem., 254 (1979) 11636-11648.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 11636-11648
-
-
Okey, A.B.1
Bondy, G.P.2
Mason, M.E.3
Kahl, G.F.4
Eisen, H.J.5
Guenthner, T.M.6
Nebert, D.W.7
-
48
-
-
0026033370
-
Novel coumarins as potential anticarcinogenic agents
-
R.V. Nair, E.P. Fisher, S. Safe, C. Cortez, R.G. Harvey and J. DiGiovanni, Novel coumarins as potential anticarcinogenic agents, Carcinogenesis, 12 (1991) 65-70.
-
(1991)
Carcinogenesis
, vol.12
, pp. 65-70
-
-
Nair, R.V.1
Fisher, E.P.2
Safe, S.3
Cortez, C.4
Harvey, R.G.5
DiGiovanni, J.6
-
49
-
-
0027426274
-
6-Substituted 3,4-benzocoumarins: A new structural class of inducers and inhibitors of CYP1A1-dependent activity
-
H. Liu, M. Santostefano, Y. Lu and S. Safe, 6-Substituted 3,4-benzocoumarins: a new structural class of inducers and inhibitors of CYP1A1-dependent activity, Arch. Biochem. Biophys., 306 (1993) 223-281.
-
(1993)
Arch. Biochem. Biophys.
, vol.306
, pp. 223-281
-
-
Liu, H.1
Santostefano, M.2
Lu, Y.3
Safe, S.4
-
50
-
-
0027930777
-
2-Phenyl phenanthridinone and related compounds: Aryl hydrocarbon receptor agonists and suicide inactivators of P4501A1
-
H. Liu, M. Santostefano and S. Safe, 2-Phenyl phenanthridinone and related compounds: aryl hydrocarbon receptor agonists and suicide inactivators of P4501A1, Arch. Biochem. Biophys., 313 (1994) 206-214.
-
(1994)
Arch. Biochem. Biophys.
, vol.313
, pp. 206-214
-
-
Liu, H.1
Santostefano, M.2
Safe, S.3
-
51
-
-
0023617650
-
Synthesis and aryl hydrocarbon receptor binding properties of radiolabeled polychlorinated dibenzofuran congeners
-
K. Farrell, L. Safe and S. Safe, Synthesis and aryl hydrocarbon receptor binding properties of radiolabeled polychlorinated dibenzofuran congeners, Arch. Biochem. Biophys., 259 (1987) 185-195.
-
(1987)
Arch. Biochem. Biophys.
, vol.259
, pp. 185-195
-
-
Farrell, K.1
Safe, L.2
Safe, S.3
-
52
-
-
0021247878
-
Binding of benzo[a]pyrene and dibenz[a,h]anthracene to the Ah receptor in mouse and rat hepatic cytosols
-
A.B. Okey, A.W. Dubé and L.M. Vella, Binding of benzo[a]pyrene and dibenz[a,h]anthracene to the Ah receptor in mouse and rat hepatic cytosols, Cancer Res., 44 (1984) 1426-1432.
-
(1984)
Cancer Res.
, vol.44
, pp. 1426-1432
-
-
Okey, A.B.1
Dubé, A.W.2
Vella, L.M.3
-
53
-
-
0023617544
-
Ah receptor in human placenta: Stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo[a]pyrene
-
D.K. Manchester, S.K. Gordon, C.L. Golas, E.A. Roberts and A.B. Okey, Ah receptor in human placenta: stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo[a]pyrene, Cancer Res., 47 (1987) 4861-4868.
-
(1987)
Cancer Res.
, vol.47
, pp. 4861-4868
-
-
Manchester, D.K.1
Gordon, S.K.2
Golas, C.L.3
Roberts, E.A.4
Okey, A.B.5
-
54
-
-
0028815347
-
Identification of 3′-methoxy-4′-nitroflavone as a pure aryl hydrocarbon receptor antagonist and evidence for more than one form of the Ah receptor in MCF-7 human breast cancer cells
-
Y. Lu, M. Santostefano, D.M. Cunningham, M.D. Threadgill and S. Safe, Identification of 3′-methoxy-4′-nitroflavone as a pure aryl hydrocarbon receptor antagonist and evidence for more than one form of the Ah receptor in MCF-7 human breast cancer cells, Arch. Biochem. Biophys., 316 (1995) 470-477.
-
(1995)
Arch. Biochem. Biophys.
, vol.316
, pp. 470-477
-
-
Lu, Y.1
Santostefano, M.2
Cunningham, D.M.3
Threadgill, M.D.4
Safe, S.5
-
55
-
-
0027978227
-
Effect of ligand structure on formation and DNA binding of the transformed rat cytosolic aryl hydrocarbon receptor
-
M. Santostefano, H. Liu, X. Wang, K. Chaloupka and S. Safe, Effect of ligand structure on formation and DNA binding of the transformed rat cytosolic aryl hydrocarbon receptor, Chem. Res. Toxicol., 7 (1994) 544-550.
-
(1994)
Chem. Res. Toxicol.
, vol.7
, pp. 544-550
-
-
Santostefano, M.1
Liu, H.2
Wang, X.3
Chaloupka, K.4
Safe, S.5
-
56
-
-
0026725943
-
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
-
K.M. Burbach, A.B. Poland and C.A. Bradfield, Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor, Proc. Natl. Acad. Sci. USA, 89 (1992) 8185-8189.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 8185-8189
-
-
Burbach, K.M.1
Poland, A.B.2
Bradfield, C.A.3
-
57
-
-
0026691255
-
6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: Evidence for the role of the Ah receptor
-
T. Zacharewski, M. Harris, L. Siegel, V. Morrison, M. Merchant and S. Safe, 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: evidence for the role of the Ah receptor, Toxicol. Appl. Pharmacol., 13 (1992) 311-318.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.13
, pp. 311-318
-
-
Zacharewski, T.1
Harris, M.2
Siegel, L.3
Morrison, V.4
Merchant, M.5
Safe, S.6
-
58
-
-
33751385798
-
Binding of transformed Ah receptor complex to a dioxin responsive transcriptional enhancer: Evidence for two distinct heteromeric DNA-binding forms
-
H.I. Swanson, K. Tullis and M.S. Denison, Binding of transformed Ah receptor complex to a dioxin responsive transcriptional enhancer: evidence for two distinct heteromeric DNA-binding forms, Biochemistry, 32 (1993) 12841-12849.
-
(1993)
Biochemistry
, vol.32
, pp. 12841-12849
-
-
Swanson, H.I.1
Tullis, K.2
Denison, M.S.3
-
59
-
-
58149209724
-
Comparative properties of the nuclear Ah receptor complex from several human cell lines
-
X. Wang, J.S. Thomsen, M. Santostefano, R. Rosengren, S. Safe and G.H. Perdew, Comparative properties of the nuclear Ah receptor complex from several human cell lines, Eur. J. Pharmacol., 293 (1995) 191-205.
-
(1995)
Eur. J. Pharmacol.
, vol.293
, pp. 191-205
-
-
Wang, X.1
Thomsen, J.S.2
Santostefano, M.3
Rosengren, R.4
Safe, S.5
Perdew, G.H.6
|