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For recent examples, see: (a) Shepard, M. S.; Carreira, E. M. J. Am. Chem. Soc. 1997, 119, 2597. (b) Ikeda, I.; Honda, K.; Osawa, E.; Shiro, M; Aso, M.; Kanematsu, K. J. Org. Chem. 1996, 61, 2031. (c) Borzilleri, R. M.; Weinreb, S. M.; Parvez, M. J. Am. Chem. Soc. 1995, 117, 10905. (d) Masse, C. E.; Panek, J. S. Chem. Rev. 1995, 95, 1293. (e) Ikeda, I.; Kanematsu, K. J. Chem. Soc., Chem. Commun. 1995, 453. (f) Marshall, J. A.; Perkins, J. J. Org. Chem. 1994, 59, 3509. (g) Carreira, E. M.; Hastings, C. A.; Shepard, M. S.; Yerkey, L. A.; Millward, D. B. J. Am. Chem. Soc. 1994, 116, 6622. (h) De Schrijver, J.; De Clercq, P. L. Tetrahedron Lett. 1993, 34, 4369. (i) Matsumoto, Y.; Naito, M.; Uozumi, Y.; Hayashi, T. J. Chem. Soc., Chem. Commun. 1993, 1468. (j) Myers, A. G.; Condroski, K. R. J. Am. Chem. Soc. 1993, 115, 7926.
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Portions of this work were orally presented at the 70th Symposium on Organic Synthesis, Japan; November 6-8, 1996, Tokyo (Urabe, H.; Suzuki, K.; Takeda, T.; Hideura, D.; Sato, F. Abstr. of the Symposium 1996, 17) and at the 72nd Annual Meeting of the Chemical Society of Japan; March 27-30, 1997, Tokyo (Hideura, D.; Takeda, T.; Urabe, H.; Sato, F. Abstr. II 1997, 874. Takeda, T.; Urabe, H.; Sato, F. Abstr. II 1997, 875).
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The ee's of the samples, 19, 22, 46, and 54, may be somewhat lower than the specified values.
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One referee suggested the possibility of another isomer shown below. However, its contribution is much less likely due to the highly strained structure. (Matrix Presented)
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