The mechanism of locally enhanced production of tumor necrosis factor-α in tumor tissues by the administration of a new synthetic lipid A analog, ONO-4007, in hepatoma-bearing rats

Anti-Cancer Drugs

Volumn 8, Issue 9, 1997, Pages 886-893

  Kuramitsu, Yasuhiro ^a,b   Ohiro, Youichi ^a   Matsushita, Kazuhiro ^a   Obara, Manabu ^a   Kobayashi, Masanobu ^a   Hosokawa, Masuo ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hepatocellular carcinoma; Lipid A; ONO 4007; Tumor necrosis factor

Indexed keywords

2 DEOXY 3 O (9 PHENYLNONANOYL) 2 [3 (9 PHENYLNONANOYLOXY)TETRADECANOYLAMINO]GLUCOPYRANOSE 4 SULFATE; LIPID A DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; DRUG ACTIVITY; FEMALE; FIBROSARCOMA; HUMAN CELL; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN CELL; TUMOR NECROSIS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CELL LINE; COCULTURE TECHNIQUES; EXTRACELLULAR MATRIX; FEMALE; LIPID A; LIVER NEOPLASMS, EXPERIMENTAL; MACROPHAGES; MITOMYCIN; RATS; RATS, WISTAR; SPLEEN; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030725783     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199710000-00010     Document Type: Article

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