Extracellular HIV-1 tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid jurkat cells

European Journal of Immunology

Volumn 27, Issue 11, 1997, Pages 2805-2811

  Borgatti, Paola ^a,b   Zauli, Giorgio ^a   Colamussi, Maria Luisa ^a   Gibellini, Davide ^c   Previati, Maurizio ^a   Cantley, Lewis L ^b   Capitani, Silvano ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Akt PKB; Apoptosis; HIV 1; Phosphatidylinositol 3 kinase; Tat

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CD4 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSACTIVATOR PROTEIN; WORTMANNIN;

APOPTOSIS; ARTICLE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA CELL LINE; PRIORITY JOURNAL; T LYMPHOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; ENZYME ACTIVATION; EXTRACELLULAR SPACE; GENE PRODUCTS, TAT; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MICROSCOPY, CONFOCAL; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 0030723358     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830271110     Document Type: Article

References (38)

1. Jones, K. A. and Peterlin, M. B., Annu. Rev. Biochem. 1994. 63: 717.
2. Ensoli, B., Barillari, G., Zaki Salahuddin, S., Gallo, R. C. and Wong-Staal, F., Nature 1990. 345: 84.
3. Ensoli, B., Buonaguro, L., Barillari, G., Fiorelli, V., Gendelman, R., Morgan, R. A., Wingfield, P. and Gallo, R. C., J. Virol. 1993. 67: 277.
4. Zauli, G., La Placa, M., Vignoli, M., Re, M. C., Gibellini, D., Furlini, G., Milani, D., Marchisio, M., Mazzoni, M. and Capitani, S., J. Acquir. Immune Defic. Syndr. 1995. 10: 306.
5. Westendorp, M. O., Frank, R., Ochsenbauer, C., Stricker, K., Dhein, J., Walczak, H., Debatin, K. M. and Krammer, P. H., Nature 1995. 375: 497.
6. Zauli, G., Gibellini, D., Milani, D., Mazzoni, M., Borgatti, P., La Placa, M. and Capitani, S., Cancer Res. 1993. 53: 4481.
7. Zauli, G., Gibellini, D., Caputo, A., Bassini, A., Negrini, M., Monne, M., Mazzoni, M. and Capitani, S., Blood 1995. 86: 3823.
8. Zauli, G., Gibellini, D., Deleghini, C., Mischiati, C., Bassini, A., La Placa, M. and Capitani, S., J. Immunol. 1996. 157: 2216.
9. Viscidi, R. P., Mayur, K., Lederman, H. M. and Frankel, A. D., Science 1989. 246: 1606.
10. Subramanyam, M., Gutheil, W. G., Bachovchin, W. W. and Huber, B. T., J. Immunol. 1993. 150: 2544.
11. Mc Closkey, T. W., Ott, M., Tribble, E., Khan, S. A., Teichberg, S., Paul, M. O., Pahwa, S., Verdin, E. and Chirmule, N., J. Immunol. 1997. 158: 1014.
12. Li, C. J., Friedman, D. J., Wang, C., Metelev, V. and Pardee, A. B., Science 1995. 268: 229.
13. Goldstein, G., Nature Med. 1996. 1: 960.
14. Brake, D. A., Debouck, C. and Biesecher, G., J. Cell Biol. 1990. 111: 1275.
15. Barillari, G., Gendelman, R., Gallo, R. C. and Ensoli, B., Proc. Natl. Acad. Sci. USA 1993. 90: 7941.
16. Vogel, B. E., Lee, S. J., Hildebrand, A., Craig, W., Pierschbacher, M. D., Wong-Staal, F. and Ruoslahti, E., J. Cell. Biol. 1993. 121: 461.
17. Weeks, B. C., Desai, K., Loewenstein, P. M., Klotman, M. E., Klotman, P., Green, M. and Kleinman, H. K., J. Biol. Chem. 1993. 268: 5279.
18. Albini, A., Soldi, R., Giunciuglio, D., Giraudo, E., Benelli, R., Primo, L., Noonan, D., Salio, M., Camussi, G., Rocki, W. and Bussolino, F., Nature Med. 1996. 2: 1371.
19. Milani, D., Mazzoni, M., Borgatti, P., Zauli, G., Cantley, L. and Capitani, S., J. Biol. Chem. 1996. 271: 22961.
20. Yao, R. and Cooper, G. M., Science 1995. 267: 2003.
21. Franke, T. F., Kaplan, D. R., Cantley, L. C. and Toker, A., Science 1997. 275: 665.
22. Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R., Cooper, G. M., Segal, R. A., Kaplan, D. R. and Greenberg, M. E., Science 1997. 275: 661.
23. Kauffmann-Zeh, A., Rodriguez-Viciana, P., Ulrich, E., Gilbert, C., Coffer, P., Downward, J. and Evan, G., Nature 1997. 385: 544.
24. Borgatti, P., Mazzoni, M., Carini, C., Neri, L. M., Marchisio, M., Bertolaso, L., Previati, M., Zauli, G. and Capitani, S., Exp. Cell. Res. 1996. 224: 72.
25. Datta, K., Franke, T. F., Chan, T. O., Makris, A., Yang, S., Kaplan, D. R., Morrison, D. K., Golemis, E. A. and Tsichlis, P. N., Mol. Cell. Biol. 1995. 15: 2304.
26. Zauli, G., Vitale, M., Re, M. C., Furlini, G., Zamai, L., Falcieri, E., Gibellini, D., Visani, G., Davis, B. R., Capitani, S. and La Placa, M., Blood 1994. 83: 167.
27. Powis, G., Bonjouklian, R., Bergren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., Grindey, G. and Vlanos, C. J., Cancer Res. 1994. 54: 2419.
28. Vlanos, C. J., Matter, W. F., Hui. K. Y. and Brown, R. F., J. Biol. Chem. 1994. 269: 5241.
29. Panayotou, G. and Waterfield, M. D., Trends Cell. Biol. 1992. 2: 358.
30. Nakanishi, H., Brewer, K. A. and Exton, J. H., J. Biol. Chem. 1993. 268: 13.
31. Weng, Q.-P., Andrabi, K., Klippel, A., Kozlowski, M. T. and Williams, L. T., Proc. Natl. Acad. Sci. USA 1995. 92: 5744.
32. Yao, R. and Cooper, G. M., Oncogene 1996. 13: 343.
33. Cai, Y-C., Cefai, D., Schneider, H., Raab, M., Nabavi, N. and Rudd, C. E., Immunity 1995. 3: 417.
34. Ward, S. G., Wilson, A., Turner, L., Westwick, J. and Sansom, D. M., Eur. J. Immunol. 1995. 25: 526.
35. Ghiotto-Ragueneau, M., Battifora, M., Truneh, A., Waterfield, M. D. and Olive, D., Eur. J. Immunol. 1996. 26: 34.
36. Edmead, C. E., Patel, Y. I., Wilson, A., Boulougouris, G., Hall, N. D., Ward, S. G. and Sansom, D. M., J. Immunol. 1996. 157: 3290.
37. McCloskey, T. W., Ott, M., Tribble, E., Khan, S. A., Teichberg, S., Paul, M. O., Pahwa, S., Verdin, E. and Chirmule, N., J. Immunol. 1997. 158: 1014.
38. Liu, Z.-G., Hsu, H., Goeddel, D. V. and Karin, M., Cell. 1996. 87: 565.