Nef protein of HIV-1 induces apoptotic cytolysis of murine lymphoid cells independently of CD95 (Fas) and its suppression by serine/threonine protein kinase inhibitors

FEBS Letters

Volumn 417, Issue 1, 1997, Pages 61-64

  Okada, Harue ^a   Takei, Ryoichi ^a,b   Tashiro, Masato ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b ASAHI CHEMICAL INDUSTRY CO   (Japan)

Author keywords

Apoptosis; HIV 1; Murine blood cell; Nef; Protein kinase inhibitor

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; BISINDOLYLMALEIMIDE; CONCANAVALIN A; FAS ANTIGEN; FASUDIL; NEF PROTEIN; PHYTOHEMAGGLUTININ; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOID CELL; NONHUMAN; PRIORITY JOURNAL;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANTIGENS, CD95; APOPTOSIS; CELL LINE; ENZYME INHIBITORS; GENE PRODUCTS, NEF; HIV-1; HUMANS; LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MURINAE;

EID: 0030717477     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01255-6     Document Type: Article

References (17)

1. Ho D.D., Neuman A.U., Perelson A.S., Chen W., Leonard J.M., Markowitz M. Nature. 373:1995;123-126.
2. Pitrak D.L., Tsai H.C., Mullane K.M., Sutton S.H., Stevens P. J. Clin. Invest. 98:1996;2714-2719.
3. Boudet F., Lecoeur H., Gougeon M.L. J. Immunol. 156:1996;2282-2293.
4. Gougeon M.-L., Lecoeur H., Dulioust A., Enouf M.-L., Crouvoisier M., Goujard C., Debord T., Montagnier L. J. Immunol. 156:1996;3509-3522.
5. Fujii Y., Otake K., Tashiro M., Adachi A. FEBS Lett. 393:1996;93-96.
6. Fujii Y., Otake K., Tashiro M., Adachi A. FEBS Lett. 391:1996;105-108.
7. Fujii Y., Otake K., Tashiro M., Adachi A. J. Gen. Virol. 77:1996;2943-2951.
8. Okada, H., Takei, R. and Tashiro, M. (1997) FEBS Lett. (in press).
9. Nunn M.F., Marsh J.W. J. Virol. 70:1996;6157-6161.
10. Asano T., Ikegaki I., Satoh S., Shibuya M., Takayasu M., Hidaka H. J. Pharmacol. Exp. Ther. 241:1987;1033-1040.
11. Asano T., Suzuki T., Tsuchiya M., Ikegaki I., Shibuya T., Suzuki Y., Hidaka H. Br. J. Pharmacol. 98:1989;1091-1100.
12. Shibuya M., Suzuki T., Sugita K., Saito I., Sasaki T., Takakura K., Nagata I., Kikuchi H., Takemae T., Hidaka H., Nakashima M. J. Neurosurg. 76:1992;571-577.
13. Nicoletti I., Migliorati G., Pagliacci M.C., Grinani F., Riccaridi C. J. Immunol. Methods. 139:1991;271-279.
14. Ruiz-Ruiz M.C., Izquierdo M., de Murcia G., Lpez-Rivas A. Eur. J. Immunol. 27:1997;1442-1450.
15. Westendorp M.O., Frank R., Ochsenbauer C., Stricker K., Dhein J., Walczak H., Debatin K.M., Krammer P.H. Nature. 375:1995;497-500.
16. Seto M., Sasaki Y., Sasaki Y., Hidaka H. Eur. J. Pharmacol. 195:1991;267-272.
17. Maecker H.T., Hedjbeli S., Alzona M., Le P.T. Exp. Cell Res. 222:1996;95-102.