Analysis of a commercially improved Penicillium chrysogenum strain series: Involvement of recombinogenic regions in amplification and deletion of the penicillin biosynthesis gene cluster

Journal of Industrial Microbiology and Biotechnology

Volumn 19, Issue 1, 1997, Pages 18-27

  Newbert, R W ^a   Barton, B ^b   Greaves, P ^b   Harper, J ^a   Turner, G ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

lactam; Amplification; Penicillin; Recombination; Strain improvement

Indexed keywords

PENICILLIN G;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; FUNGUS MUTATION; GENE AMPLIFICATION; GENE CLUSTER; GENE DELETION; GENETIC RECOMBINATION; NONHUMAN; PENICILLIUM CHRYSOGENUM; PROMOTER REGION; SCREENING;

CHROMOSOME MAPPING; GENE AMPLIFICATION; MULTIGENE FAMILY; PENICILLINS; PENICILLIUM CHRYSOGENUM; PROMOTER REGIONS (GENETICS); RECOMBINATION, GENETIC; REPETITIVE SEQUENCES, NUCLEIC ACID;

FUNGI; PENICILLIUM; PENICILLIUM CHRYSOGENUM;

EID: 0030716357     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.2900411     Document Type: Article

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