cDNA cloning and chromosomal mapping of a predicted coiled-coil proline-rich protein immunogenic in meningioma patients

Human Molecular Genetics

Volumn 6, Issue 12, 1997, Pages 2031-2041

  Heckel, Dirk ^a   Brass, Nicole ^a   Fischer, Ulrike ^a   Blin, Nikolaus ^a   Steudel, Ingo ^a   Türeci, Özlem ^b   Fackler, Oliver ^c   Zang, Klaus D ^a   Meese, Eckart ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GLYCOPROTEIN P; PROLINE; TUMOR ANTIGEN;

ARTICLE; CHROMOSOME 13; CHROMOSOME 14; CHROMOSOME 2; CHROMOSOME 3; CHROMOSOME 6; CHROMOSOME 7; CHROMOSOME 9; CHROMOSOME MAP; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOREACTIVITY; MENINGIOMA; MOLECULAR CLONING; NORTHERN BLOTTING; OPEN READING FRAME; PRIORITY JOURNAL;

EID: 0030714173     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/6.12.2031     Document Type: Article

References (22)

1. Russel,D.S and Rubinstein,L.J. (1989) Pathology of Tumours of the Nervous System. Edward Arnold, London, Melbourne, Auckland 449-532.
2. Zang,K.D. and Singer,H. (1967) Chromosomal constitution of meningiomas. Nature 216, 84-85.
3. Meese,E.U., Blin,N. and Zang,K.D. (1987) Loss of heterozygosity and the origin of meningioma. Human Genet. 77, 349-351.
4. Dumanski,J.P., Rouleau,G.A., Nordenskjold,M. and Collins,V.P. (1990) Molecular genetic analysis of chromosome 22 in 81 cases of meningioma. Cancer Res. 50, 5863-5867.
5. Ruttledge,M.H., Sarrazin,J., Rangaratnam,S., Phelan,C.M., Twist,E., Merel,P., Delattre,O., Thomas,G., Nordenskjold,M., Collins,V.P., Dumanski,J.P. and Rouleau,G.A. (1994) Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas. Nature Genet. 6, 180-184.
6. Murphy,M., Pykett,M.J., Hamish,P., Zang,K.D. and George,D.L. (1993) Identification and characterization of genes differentially expressed in meningiomas. Cell Growth Differ. 4, 715-722.
7. Lekanne Deprez,R.H., Riegman,P.H, van Drunen,E., Warringa,U.L., Groen,N.A., Stefanko,S.Z., Koper,J.W., Avezaat,C.J.J., Mulder,P.G.H., Zwarthoff,E.C. and Hagemeijer,A. (1995) Cytogenetic, molecular genetic and pathological analyses in 126 meningiomas. J. Neuropath. Exp. Neurol. 54, 224-235.
8. Ben-Mahrez,K., Sorokine,I., Thierry,D., Kawasumi,T., Ishi,S., Salmon,R. and Kohiyama,M. (1990) Circulating antibodies against c-myc oncogene product in sera of colorectal cancer patients. Int. J. Cancer 46, 35-38.
9. Brass,N., Heckel,D., Sahin,U., Pfreundschuh,M., Sybrecht,G. and Meese,E. (1997) Translation initiation factor eIF-4gamma is encoded by an amplified gene and induces an immune response in squamous cell lung carcinoma. Hum. Mol. Genet. 6, 33-39.
10. Disis,M.L., Calenoff,E., McLaughlin,G., Murphy,A.E., Cehn,W., Groner,B., Jeschke,B., Lydon,N., McGlynn,E., Livingston,R.B., Moe,R. and Cheever,M.A. (1994) Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer. Cancer Res. 54, 16-20.
11. Schlichtholz,B., Legros,Y., Gillet,D., Gaillard,C., Marty,M., Lane,D., Calvo,F. and Soussi,T. (1992) The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot. Cancer Res. 52, 6380-6384.
12. Sorokine,I., Ben-Mahrez,K., Bracone,A., Thierry,D., Ishi,S., Imamoto,F. and Kohiyama,M. (1991) Presence of circulating anti-c-myc oncogene product antibodies in human sera. Int. J. Cancer 47, 665-669.
13. Sahin,U., Tureci,O., Schmitt,H., Cochlovius,B., Johannes,T., Schmits,R., Luo,G., Schobert,I. and Pfreundschuh,M. (1996) Human neoplasms elicit multiple specific immune responses in the autologous host. Proc. Natl. Acad. Sci. USA 92, 11810-11813.
14. Tureci,Ö., Sahin,U., Schobert,I., Koslowski,M., Schmitt,H., Schild,H.J., Rammensee,H.G., Seitz,G. and Pfreundschuh,M. (1996) The SSX-2 gene, which is involved in the t(X; 18) translocation of synovial sarcomes codes for the human tumor antigen HOM-MEL-40. Cancer Res. 56, 4766-4772.
15. Lupas,A., Van Dyke,M. and Stock,J. (1991) Predicting coiled coiles from protein sequences. Science 252, 1162-1164.
16. Nagase,T., Seki,N., Ishikawa,K., Ohara,O. and Nomura,N. (1996) Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from human cell line KG-1 and brain. DNA Res. 3, 321-329.
17. Norris,M.D., Gilbert,J., Madafiglio,J. and Haber,M. (1995) Analysis of a novel cDNA encoding a C219-reactive peptide isolated from methotrexate-selected multidrug-resistant human leukemic cells. Gene 156, 313-314.
18. Harborth,J., Weber,K. and Osborn,M. (1995) Epitope mapping and direct visualization of the parallel, in register arrangement of the double-stranded coiled-coil in the NuMA protein. EMBO J. 14, 2447-2460.
19. Artandi,S.E., Merrell,K., Avitahl,N., Wong,K.K. and Calame,K. (1995) TFE3 contains two actication domains, one acidic and the other proline-rich, that synergistically activate transcription. Nucleic Acids Res. 23, 3865-3871.
20. Marcias,M.J., Hyvonen,M., Baraldi,E., Schultz,J., Sudol,M., Saraste,M. and Oschkinat,H. (1996) Structure of the WW-domain of a kinase associated protein complexed with a proline-rich peptide. Nature 382, 646-649.
21. Alexandropoulos,K., Cheng,G. and Baltimore,D. (1995) Proline-rich , sequences that bind to SRC homology 3 domains with individual specificities. Proc. Natl. Acad. Sci. USA 92, 3110-3114.
22. Lekanne-Deprez,R.H. (1995) Cytogenetic, molecular genetic and pathological analyses in 126 meningiomas. J. Neuropath. Exp. Neurol. 54, 224-235.