Hemihypertrophy: Concepts and controversies

Journal of Bone and Joint Surgery

Volumn 79, Issue 11, 1997, Pages 1731-1738

  Ballock, R Tracy ^a,b   Wiesner, Georgia L ^a,b   Myers, Melissa T ^a,c   Thompson, George H ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOOSTEOHYPERTROPHY SYNDROME; BECKWITH WIEDEMANN SYNDROME; BONE MATURATION; CHILDHOOD CANCER; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; ECHOGRAPHY; HEMIHYPERTROPHY; HUMAN; LEG LENGTH INEQUALITY; MULTIPLE CANCER; NEUROFIBROMATOSIS; PRIORITY JOURNAL; REVIEW; SCREENING;

EID: 0030709478     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/00004623-199711000-00016     Document Type: Review

References (67)

1. Anderson, M.; Messner, M. B.; and Green, W. T.: Distribution of lengths of the normal femur and tibia in children from one to eighteen years of age. J. Bone and Joint Surg., 46-A: 1197-1202, Sept. 1964.
2. Andrews, M. W., and Amparo, E. G.: Wilms' tumor in a patient with Beckwith-Wiedemann syndrome: onset detected with 3-month serial sonography. AJR: Am. J. Roentgenol., 160: 139-140, 1993.
3. Azouz, E. M.; Larson, E. J.; Patel, J.; and Gyepes, M. T.: Beckwith-Wiedemann syndrome: development of nephroblastoma during the surveillance period. Pediat. Radiol., 20: 550-552, 1990.
4. Beals, R. K.: Hemihypertrophy and hemihypotrophy. Clin. Onthop., 166: 199-203, 1982.
5. Beckwith, J. B.: Extreme cytomegaly of the adrenal fetal cortex, omphalocele, hyperplasia of kidneys and pancreas, and Leydig-cell hyperplasia. Another syndrome? Read at the Annual Meeting of the Western Society for Pediatric Research, Los Angeles, California, Nov. 11, 1963.
6. Beckwith, J. B.: Macroglossia, omphalocele, adrenal cytomegaly, gigantism, and hyperplastic visceromegaly. Birth Defects, 5: 188-196, 1969.
7. Beckwith, J. B.: Questions and answers. AJR: Am. J. Roentgenol., 164: 1294-1295, 1995.
8. Behrman, R. E.; Kliegman, R. M.; and Arvin, A. M. [editors]: Nelson Textbook of Pediatrics. Ed. 15. Philadelphia, W. B. Saunders, 1996.
9. Boxer, L. A., and Smith, D. L.: Wilms' tumor prior to onset of hemihypertrophy. Am. J. Dis. Child., 120: 564-565, 1970.
10. Breslow, N.; Beckwith, J. B.; Ciol, M.; and Sharples, K.: Age distribution of Wilms' tumor: report from the National Wilms' Tumor Study. Cancer Res., 48: 1653-1657, 1988.
11. Clericuzio, C. L.: Clinical phenotypes and Wilms tumor. Med. and Pediat. Oncol., 21: 182-187, 1993.
12. Clericuzio, C. L., and Johnson, C.: Screening for Wilms tumor in high-risk individuals. Hematol./Oncol. Clin. North America, 9: 1253-1265, 1995.
13. Cohen, M. M., Jr.: A comprehensive and critical assessment of overgrowth and overgrowth syndromes. Adv. Hum. Genet., 18: 181-303, 373-376, 1989.
14. Cohen, M. M., Jr.: Wiedemann-Beckwith syndrome, imprinting, IGF2, and H19: implications for hemihvperplasia, associated neoplasms, and overgrowth [letter]. Am. J. Med. Genet., 52: 233-234, 1994.
15. Consensus Development Conference: Neurofibromatosis. Conference statement. Arch. Neurol., 45: 575-578, 1988.
16. Craft, A. W.; Parker, L.; Stiller, C.; and Cole, M.: Screening for Wilms' tumour in patients with aniridia, Beckwith syndrome, or hemihypertrophy. Med. and Pediat. Oncol., 24: 231-234, 1995.
17. Demetriades, D.; Hager, J.; Nikolaides, N.; Malamitsi-Puchner, A.; and Bartsocas, C. S.: Proteus syndrome: musculoskeletal manifestations and management: a report of two cases. J. Pediat. Onthop., 12: 106-113, 1992.
18. Elliott, M., and Maher, E. R.: Beckwith-Wiedemann syndrome. J. Med. Genet., 31: 560-564, 1994.
19. Elliott, M.; Bayly, R.; Cole, T.; Temple, I. K.; and Maher, E. R.: Clinical features and natural history of Beckwith-Wiedemann syndrome: presentation of 74 new cases, Clin. Genet., 46: 168-174, 1994.
20. Filippi, G., and McKusick, V. A.: The Beckwith-Wiedemann syndrome (the exomphalos-macroglossia-gigantism syndrome). Report of two cases and review of the literature. Medicine, 49: 279-298, 1970.
21. Fraumeni, J. F., Jr., and Miller, R. W.: Adrenocortical neoplasms with hemihypertrophy, brain tumors, and other disorders. J. Pediat., 70: 129-138, 1967.
22. Fraumeni, J. F., Jr.; Geiser, C. F.; and Manning, M. D.: Wilms' tumor and congenital hemihypertrophy: report of five new cases and review of literature. Pediatrics, 40: 886-899, 1967.
23. Fraumeni, J. F., Jr.; Miller, R. W.; and Hill, J. A.: Primary carcinoma of the liver in childhood: an epidemiologic study. J. Nat. Cancer Inst., 40: 1087-1099, 1968.
24. Furukawa, T., and Shinohara, T.: Congenital hemihypertrophy: oncogenic potential of the hypertrophie side. Am. J. Neurol., 10: 199-201, 1981.
25. Green, D. M.; Breslow, N. E.; Beckwith, J. B.; and Norkool, P.: Screening of children with hemihypertrophy, aniridia, and Beckwith-Wiedemann syndrome in patients with Wilms tumor: a report from the National Wilms Tumor Study. Med. and Pediat. Oncol., 21: 188-192, 1993.
26. Green, D. M.; Beckwith, J. B.; Breslow, N. E.; Faria, P.; Moksness, J.; Finkelstein, J. Z.; Grundy, P.; Thomas, P. R. M.; Kim, T.; Shochat, S.; Haase, G.; Ritchey, M.; Kelalis, P.; and D'Angio, G. J.: Treatment of children with stages II to IV anaplastic Wilms' tumor: a report from the National Wilms' Tumor Study Group. J. Clin. Oncol., 12: 2126-2131, 1994.
27. Haicken, B. N.; Schulman, N. H.; and Schneider, K. M.: Adrenocortical carcinoma and congenital hemihypertrophy. J. Pediat., 83: 284-285, 1973.
28. Harris, R. E.; Fuchs, E. F.; and Kaempf, M. J.: Medullary sponge kidney and congenital hemihypertrophy: case report and literature review. J. Urol., 126: 676-678, 1981.
29. Hennessy, W. T.; Cromie, W. J.; and Duckett, J. W.: Congenital hemihypertrophy and associated abdominal lesions. Urology, 18: 576-579, 1981.
30. Higurashi, M.; Iijima, K.; Sugimoto, Y.; Ishikawa, N.; Hoshina, H.; Watanabe, N.; and Yoneyama, K.: The birth prevalence of malformation syndromes in Tokyo infants: a survey of 14,430 newborn infants. Am. J. Med. Genet., 6: 189-194, 1980.
31. Hoyme, H. E.; Procopio, F.; Crooks, W.; Feingold, M.; and Jones, K. L.: The incidence of neoplasia in children with isolated congenital hypertrophy [abstract]. Proc. Greenwood Genet. Center, 6: 126, 1987.
32. Huang, W. J., and Creath, C. J.: Klippel-Trenaunay-Weber syndrome: literature review and case report. Pediat. Dent., 16: 231-235, 1994.
33. Jones, K. L.: The etiology and diagnosis of overgrowth syndromes. Growth Genet. and Horm., 10: 6-10, 1994.
34. Kinzler, K. W., and Vogelstein, B.: Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
35. Koufos, A.; Grundy, P.; Morgan, K.; Aleck, K. A.; Hadro, T.; Lampkin, B. C.; Kalbakji, A.; and Cavenee, W. K.: Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5. Am. J. Hum. Genet., 44: 711-719, 1989.
36. Leck, I.; Record, R. G.; McKeown, T.; and Edwards, J. H.: The incidence of malformation in Birmingham, England (1950-1959). Teratology, 1: 263-280, 1968.
37. Letts, R. M.: Orthopaedic treatment of hemangiomatous hypertrophy of the lower extremity. J. Bone and Joint Surg., 59-A: 777-783, Sept. 1977.
38. MacEwen, G. D., and Case, J. L.: Congenital hemihypertrophy. A review of 32 cases. Clin. Orthop., 50: 147-150, 1967.
39. Meadows, A. T.; Lichtenfeld, J. L.; and Koop, C. E.: Wilms's tumor in three children of a woman with congenital hemihypertrophy. New England J. Med., 291: 23-24, 1974.
40. Miller, R. W.: Relation between cancer and congenital defects: an epidemiologic evaluation. J. Nat. Cancer Inst., 40: 1079-1085, 1968.
41. Miller, R. W.; Fraumeni, J. F.; and Manning, M. D.: Association of Wilms's tumor with aniridia, hemihypertrophy and other congenital malformations. New England J. Med., 270: 922-927, 1964.
42. Morrissy, R. T., and Weinstein, S. L. [editors]: Lovell and Winter's Pediatric Orthopaedics. Ed. 4. Philadelphia, Lippincott-Raven, 1996.
43. Mullins, J. F.; Naylor, D.; and Redetsky, J.: The Klippel-Trenaunay-Weber syndrome. Naevus vasculosus osteohypertrophicus. Arch. Dermatol., 86: 202-206, 1962.
44. Newsham, I.; Kindler-Rohrborn, A.; Daub, D.; and Cavenee, W.: A constitutional BWS-related t(11;16) chromosome translocation occurring in the same region of chromosome 16 implicated in Wilms' tumors. Genes, Chrom, and Cancer, 12: 1-7, 1995.
45. Pappas, A. M., and Nehme, A.M.: Leg length discrepancy associated with hypertrophy. Clin. Orthop., 144: 198-211, 1979.
46. Parker, D. A., and Skalko, R. G.: Congenital asymmetry: report of 10 cases with associated developmental abnormalities. Pediatrics, 44: 584-589, 1969.
47. Parker, L.; Kollin, J.; Vicario, D.; and Nguyen, T.: Hemihypertrophy as possible sign of renal cell carcinoma. Urology, 40: 286-288, 1992.
48. Pearn, J.; Viljoen, D.; and Beighton, P.: Limb overgrowth - clinical observations and nosological considerations. South African Med. J., 64: 905-908, 1983.
49. Pendergrass, T. W.: Congenital anomalies in children with Wilms' tumor: a new survey. Cancer, 37: 403-408, 1976.
50. Ping, A. J.; Reeve, A. E.; Law, D. J.; Young, M. R.; Boehnke, M.; and Feinberg, A. P.: Genetic linkage of Beckwith-Wiedemann syndrome to 11p15. Am. J. Hum. Genet., 44: 720-723, 1989.
51. Ringrose, R. E.; Jabbour, J. T.; and Keele, D.K.: Hemihypertrophy. Pediatrics, 36: 434-448, 1965.
52. Rudolph, C. E., and Norvold, R. W.: Congenital partial hemihypertrophy involving marked malocclusion. J. Dent. Res., 23: 133-139, 1944.
53. Rush, W. A., and Steiner, H. A.: A study of lower extremity length inequality. Am. J. Roentgenol., 56: 616-623, 1946.
54. Shah, K. J.: Beckwith-Wiedemann syndrome: role of ultrasound in its management. Clin. Radiol., 34: 313-319, 1983.
55. Sotelo-Avila, C., and Gooch, W. M., III: Neoplasms associated with the Beckwith-Wiedemann syndrome. Penpect. Pediat. Pathol., 3: 255-272, 1976.
56. Sotelo-Avila, C.; Gonzalez-Crussi, F.; and Fowler, J. W.: Complete and incomplete forms of Beckwith-Wiedemann syndrome: their oncogenic potential. J. Pediat., 96: 47-50, 1980.
57. Stevenson, R. E., and Meyer, L. C.: The Limbs. In Oxford Monographs on Medical Genetics. No. 27. Human Malformations amd Related Anomalies, edited by R. E. Stevenson. J. G. Hall, and R. M. Goodman. Vol. 2. pp. 778-785. New York, Oxford University Press, 1993.
58. Stricker, S.: Musculoskeletal manifestations of Proteus syndrome: report of two cases with literature review. J. Pediat. Orthop., 12: 667-674, 1992.
59. Tachdjian, M. O.: Pediatric Orthopaedics. Ed. 2. Philadelphia. W. B. Saunders, 1990.
60. Viljoen, D.; Pearn, J.; and Beighton, P.: Manifestations and natural history of idiopathic hemihypertrophy: a review of eleven cases. Clin. Genet., 26: 81-86, 1984.
61. Ward, J., and Lerner, H. H.: A review of the subject of congenital hemihypertrophy and a complete case report. J. Pediat., 31: 403-414, 1947.
62. Waziri, M.; Patil, S. R.; Hanson, J. W.; and Bartley, J. A.: Abnormality of chromosome 11 in patients with features of Beckwith-Wiedemann syndrome. J. Pediat., 102: 873-876, 1983.
63. Weksberg, R.: Wiedemann-Beckwith syndrome: genomic imprinting revisited. Am. J. Med. Genet., 52: 235-236, 1994.
64. Weng, E. Y.; Mortier, G. R.; and Graham, J. M., Jr.: Beckwith-Wiedemann syndrome. An update and review for the primary pediatrician. Clin. Pediat., 34: 317-326, 1995.
65. Wiedemann, H. R.: Complexe malformatif familial avec hernia ombilicale et macroglossie - un "syndrome neouveau"? J. Génét. Hum., 13: 223-232, 1964.
66. Wiedemann, H.-R.: Tumours and hemihypertrophy associated with Wiedemann-Beckwith syndrome [letter]. European J. Pediat., 141: 129, 1983.
67. Wiedemann, H. R.; Burgio, G. R.; Aldenhoff, P.; Kunze, J.; Kaufmann, H. J.; and Schirg, E.: The Proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy. subcutaneous tumors, macrocephaly or other skull anomalies and possible accelerated growth and visceral affections. European J. Pediat., 140: 5-12, 1983.