Effects of gastrin-releasing peptide (GRP) on the mechanical activity of the human ileocaecal region in vitro

Neurogastroenterology and Motility

Volumn 9, Issue 4, 1997, Pages 265-270

  Vadokas, B ^a   Ludtke F E ^a   Lepsien, G ^a   Golenhofen, K ^b   Mandrek, K ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Gastrin releasing peptide (GRP); Human ileocaecal region; In vitro; Mechanical activity

Indexed keywords

ADRENERGIC RECEPTOR; CHOLINERGIC RECEPTOR; GASTRIN RELEASING PEPTIDE; PENTAGASTRIN; TETRODOTOXIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT; HUMAN; HUMAN TISSUE; NERVE BLOCK; PRIORITY JOURNAL; SMOOTH MUSCLE; SMOOTH MUSCLE TONE;

EID: 0030704243     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.1997.d01-59.x     Document Type: Article

References (26)

1. McDonald TJ, Jörnvall H, Nilsson G, et al. Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue. Biochem Biophys Res Commun 1979; 90: 227-33.
2. Walsh JH. Bombesin-like peptides. In: Schultz SG, Makhlouf GM, eds. Handbook of Physiology. Bethesda: American Physiological Society, 1989; sect. 6, Vol. II, 587-610.
3. Bunnett N. Gastrin-releasing peptide. In: Walsh JH, Dockray GJ, eds. Gut Peptides. New York: Raven Press Ltd, 1994, 423-45.
4. Daniel EE, Collins SM, Fox JET, Huizinga JD. Pharmacology of neuroendocrine peptides. In: Schultz SG, Wood JD, eds. Handbook of Physiology. Bethesda: American Physiological Society, 1989; sect 6, Vol. I, 759-816.
5. Girard F, Bachelard H, St-Pierre S, Rioux F. The contractile effect of bombesin, gastrin-releasing peptide and various fragments in the rat stomach strip. Eur J Pharmacol 1984; 102: 489-97.
6. Mayer EA, Elashoff J, Walsh JH. Characterization of bombesin effects on canine gastric muscle. Am J Physiol 1982; 243: G141-7.
7. Lüdtke FE, Golenhofen K, Becker HD. Mechanical activity of isolated human pyloric muscle, in comparison with canine pylorus. In: Roman C, ed. Gastrointestinal Motility. Lancaster: MTP Press, 1984; 87-94.
8. Dockray GJ. Physiology of enteric neuropeptides. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract, 3rd edn. New York: Raven Press, 1994, 169-206.
9. Yegen BC, Gürbüz V, Coskun T, et al. Inhibitory effects of gastrin releasing peptide on gastric emptying in rats. Regul Pept 1996:175-80.
10. Angel F, Go VLW, Szurszewski JH. Innervation of muscularis mucosae of canine proximal colon. J Physiol 1984; 357: 93-108.
11. Lüdtke FE, Pogrzeba B, Mandrek K, Lepsien G, Neufang T, Golenhofen K. Bombesin - the most stimulating peptide of human gastric smooth muscle. Dig Dis 1991; 9: 414-31.
12. Pogrzeba B, Mandrek K, Lüdtke FE, Lepsien G, Golenhofen K. Contractile action of gastrin-releasing peptide on isolated preparations of human gastroduodenal muscle. Dig Dis 1991; 9: 354-9.
13. Bogers JJ, Van Marck E. The ileocaecal junction. Histol Histopath 1993; 8: 561-6.
14. McKirdy HC, Marshall RW, Taylor BA. Control of human ileocaecal junction: an in vitro analysis of adrenergic and non-adrenergic non-cholinergic mechanisms. Digestion 1993; 54: 200-6.
15. Golenhofen K, During B, Mandrek K. In vitro studies of phasic and tonic components of gastrointestinal motility. In: Holle GE, et al., eds. Advances in the Innervation of the Gastrointestinal Tract. Amsterdam: Elsevier Science Publishers B.V., 1992; 221-35.
16. De Man JG, Boeckxstaens GE, De Winter BY, et al. Comparison of the pharmacological profile of S-nitrosothiols, nitric oxide and nitrergic neurotransmitter in the canine ileocolonic junction, Br J Pharmacol 1995; 114: 1179-84.
17. Phillips SF, Quigley EM, Kumar D, Kamath PS. Motility of the ileocolonic junction. Gut 1988; 29: 390-406.
18. During B, Mandrek K, Lüdtke FE, Lepsien G, Golenhofen K. Gastrin-releasing peptide modulates the mechanical activity of the human ileocecal region in vitro. Dig Dis Sci 1994; 8: 1776.
19. Golenhofen K, Mandrek K. Phasic and tonic contraction processes in the gastrointestinal tract. Dig Dis 1991; 9: 341-6.
20. Mandrek K, Golenhofen K. Phasic-rhythmical and tonic components in gastrointestinal motility. Prog Clin Biol Res 1990; 327: 463-81.
21. Micheletti R, Grider JR, Makhlouf GM. Identification of bombesin receptors on isolated muscle cells from human intestine, Regul Pept 1986, 21: 219-26.
22. Yagi H, Snape WJ Jr, Hyman PE. Perinatal changes in bombesin-stimulated muscle contraction in rabbit stomach and colon. Gastroenterology 1991; 100: 980-5.
23. Chijiiwa Y, Harada N, Misawa T, et al The direct contractile effect of gastrin releasing peptide on isolated gastric smooth muscle cells of the guinea pig. Life Sci 1991; 49: 173-8.
24. Moran TH, Moody TW, Hosteler AM, Robinson PH, Goldrich M, McHugh PR. Distribution of bombesin binding sites in the rat gastrointestinal tract. Peptides 1988; 9: 643-9.
25. Severi C, Jensen RT, Erspamer V, et al. Different receptors mediate the action of bombesin-related peptides on gastric smooth muscle cells. Am J Physiol 1991; 260: G683-90.
26. Vigna SR, Mantyh CR, Giraud AS, Soil AH, Walsh JH, Mantyh PW. Localization of specific binding sites for bombesin in the canine gastrointestinal tract. Gastroenterology 1987; 93: 1287-95.