Inhibitory effects of gastrin releasing peptide on gastric emptying in rats

Regulatory Peptides

Volumn 61, Issue 3, 1996, Pages 175-180

  Yeǧen, Berrak Ç ^a,c   Gürbüz, Vildan ^a   Coşkun, Tamer ^a   Bozkurt, Ayhan ^a   Kurtel, Hizir ^a   Alican, Inci ^a   Dockray, Graham J ^b  

^a MARMARA UNIVERSITY   (Turkey)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Gastric empyting; Gastrin releasing peptide; HCl; Peptone

Indexed keywords

BOMBESIN ANTAGONIST; BW 2258U89; GASTRIN RELEASING PEPTIDE; GASTRIN RELEASING PEPTIDE ANTAGONIST; NC 889; PEPTONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; FOOD INTAKE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH EMPTYING; STOMACH FISTULA; SUBCUTANEOUS DRUG ADMINISTRATION; TEST MEAL;

EID: 0242594257     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-0115(95)00151-4     Document Type: Article

References (44)

1. Bunnett, N., Gastrin-releasing peptide. In J.H. Walsh and GJ. Dockray, Gut Peptides: Biochemistry and Physiology, Raven Press, New York, 1994, pp. 423-445.
2. Giraud, A.S., Soll, A.H., Cuttitta, F. and Walsh, J.H., Bombesin stimulation of gastrin release from canine gastrin cells in primary culture, Am. J. Physiol., 252 (1987) G413-G420.
3. Sugano, K., Park, J., Soll, A.H. and Yamada, T., Stimulation of gastrin release by bombesin and canine gastrin-releasing peptides, J. Clin. Invest., 79 (1987) 935-942.
4. Aponte, G.W., Taylor, I.L. and Soll, A.H., Primary culture of PYY cells from canine colon, Am. J. Physiol., 254 (1988) G829-G836.
5. Walsh, J.H., Bombesinlike peptides, In D. Krieger, M. Brownstein and J. Martin (Eds.), Brain Peptides, John Wiley & Sons, New York, 1983, pp. 941-960.
6. Lundell, L., Cantor, P., Sjoval, M., Rehfeld, J.F., Olbe, L., Factors influencing the release of cholecystokinin induced by gastrin-releasing peptide in man, Scand. J. Gastroenterol., 26 (1991) 544-550.
7. Gibbs, J., Fauser, D.J., Rowe, E.A., Rolls, B.J., Rolls, E.T. and Maddison, S.P., Bombesin suppresses feeding in rats, Nature Lond., 282 (1979) 208-210.
8. Muurahainen, N.E., Kissileff, H.R. and Pi-Sunyer, F.X., Intravenous infusion of bombesin reduces food intake in humans, Am. J. Physiol, 264 (1993) R350-R354.
9. 2NH-Leu14)-Bombesin, Scand. J. Gastroenterol., 25 (1990) 89-96.
10. Scarpignato, C., Micali, B., Vitulo, B. and Zimbaro, G., Bertaccini, G., The effect of bombesin on gastric emptying of solids in man, Peptides, 2 (Suppl. 2) (1981) 199-203.
11. Corazziari, E., Torsoli, A., Delle Fave, G.F., Melchiorri, P. and Habib, F.J., Effects of bombesin on the mechanical activity of the human duodenum and jejunum, Rend. Gastroenterol., 6 (1974) 55-59.
12. Scarpignato, C. and Bertaccini, G., Bombesin delays gastric emptying in the rat, Digestion, 21 (1981) 104-106.
13. Vagne, M., Collinet, M., Cuber, J.C., Bernard, C., Chayvialle, J.A., McDonald, T.J. and Mutt, V., Effect of porcine gastrin releasing peptide on gastric secretion and motility and the release of hormonal peptides in conscious cats, Peptides, 8 (1987) 423-430.
14. Walsh, J.H., Maxwell, V., Ferrari, J. and Varner, A.A., Bombesin stimulates human gastric function by gastrin-dependent and independent mechanisms, Peptides, 2 (Suppl. 2) (1981) 193-198.
15. Kelly, K.A., Gastric emptying of liquids and solids: roles of proximal and distal stomach, Am. J. Physiol., 239 (1980) G71-G76.
16. Meyer, J.H., Motility of the stomach and the gastroduodenal junction. In L.R. Johnson, Physiology of the Gastrointestinal Tract (2nd Edn.), Raven, New York, 1987, pp. 613-629.
17. Forster, E.R., Green, T., Elliot, M., Bremner, A. and Dockray, G.J., Gastric emptying in rats: role of afferent neurons and cholecystokinin, Am. J .Physiol., 258 (1990) G552-G556.
18. Forster, E.R., Green, T. and Dockray, G.J., Efferent pathways in the reflex control of gastric emptying in rats, Am. J. Physiol., 260 (1991) G499-G504.
19. Raybould, H.E., Roberts, M.E. and Dockray, G.J., Refles decreases in intragastric pressure in response to cholecystokinin in rats, Am. J. Physiol., 253 (1987) G165-G170.
20. Raybould, H.E. and Tache, Y., Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats, Am. J. Physiol., 255 (1988) G242-G246.
21. Scarpignato, C., Capovilla, T. and Bertaccini, G., Action of caerulein on gastric emptying of conscious rat, Arch, Int. Pharmacodyn. Ther., 246 (1980) 286-294.
22. Debas, H.T., Farooq, O. and Grossman, M.I., Inhibition of gastric emptying is a physiological action of cholecystokinin, Gastroenterology, 68 (1975) 1211-1217.
23. Green, T., Dimaline, R., Peikin, S. and Dockray, G.J., Action of cholecystokinin antagonist L364,718 on gastric emptying in the rat, Am. J. Physiol., 255 (1988) G685-G689.
24. Lenz, H.J., CNS regulation of gastric and autonomie functions in dogs by gastrin-releasing peptide, Am. J. Physiol., 255 (1988) G298-G303.
25. Chikh-Issa, A.R., Scarpignato, C., Collinet, M., Chayvialle, J.A. and Vagne, M., Dual effect of bombesin and gastrin releasing peptide on gastric emptying in conscious cats, Peptides, 10 (1989) 281-287.
26. McHugh, P.R. and Moran T.H., The stomach, cholecystokinin and satiety, Fed. Proc., 45 (1986) 1384-1390.
27. Jensen, R.T. and Coy, D.H., Progress in the development of potent bombesin receptor antagonists, TIPS, 12 (1991) 13-19.
28. Singh, P., Guo, Y.-S., Kull, F.C. and Leban, J.J., A novel bombesin receptor antagonist (2258U89, potently inhibits bombesin evoked release of gastrointestinal hormones from rats and dogs, in vitro and in vivo, Regul. Pept., 40 (1992) 75-86.
29. Wiley, J.C., Lechner, J.G. and Harris, C.C., Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells, Exp. Cell Res., 153(1984)245-248.
30. von Schenck, T., Wang, L.-H., Coy, D.H., Villanueva, M.L., Mantey, S. and Jensen, R.T., Potent bombesin receptor antagonists distinguish receptor subtypes, Am. J. Physiol., 259 (1990) G468-G473.
31. Dockray, G.J., Vaillant, C. and Walsh, J.H., The neuronal origin of bombesin-like immunoreactivity in the rat gastrointestinal tract, Neuroscience, 4 (1979) 1561-1568.
32. Moghimazadeh, E., Ekman, R., Hkanson, R., Yanaihara, N. and Sundler, F., Neuronal gastrin releasing peptide in the mammalian gut and pancreas, Neuroscience, 10 (1983) 553-563.
33. Bertaccini, G., Erspamer, V., Melchiorri, P. and Sopranzi, N., Gastrin release by bombesin in the dog, Br. J. Pharm., 52 (1974) 219-225.
34. Walsh, J.H., Why does the oxyntic gland and mucosa contain gastrin-releasing peptide nerve fibers? (Editorial), Gastroenterology, 97 (1989) 793-797.
35. Coy, D., Wang, L.-H., Jiang, N.-Y. and Jensen, R., Short chain bombesin pseudopeptides with potent bombesin receptor antagonist activity in rat and guinea pig pancreatic acinar cells, Eur. J. Pharm., 190 (1990) 31-38.
36. Wang, L.-H. Coy, D.H. and Taylor, I.E., Des-met carboxyl-terminally modified analogues of bombesin function as potent receptor antagonists, partial agonists or agonists. J. Biol. Chem., 265 (1990) 15695-15703.
37. Coy, D.H., Jiang, N.-Y. and Kim, S.H., Covalently cyclized agonist and antagonist analogues of bombesin and related peptides, J. Biol. Chem., 266 (1991) 16441-16447.
38. Grider, J.R., Cable, M.B., Said, S.I. and Makhlouf, G.M., Vasoactive intestinal peptide as a neural mediator of gastric relaxation, Am. J. Physiol., 248 (1985) G73-G78.
39. De Beurme, F.A. and Lefebvre, R.A., Vasoactive intestinal polypeptide as possible mediator of relaxation in the rat gastric Fundus, J. Pharm. Pharmacol., 40 (1988) 711-715.
40. Lefebvre, R.A., Hasrat, J. and Gobert, A., Influence of NG-nitro-L-arginine methyl ester on vagally induced gastric relaxation in the anesthetized rat, Br. J. Pharm., 105 (1992) 315-320.
41. Anderson, L. and Dockray, G.J., The cholecystokinin antagonist L-364,718 inhibits the action of cholecystokinin but not bombesin on rat pancreatic secretion in vivo, Eur. J. Pharmacol., 146 (1988) 307-311.
42. Gutzwiller, J.P., Drewe, J., Hildebrand, P., Rossi, L., Lauper, J.Z. and Beglinger, C., Effect of intravenous human gastrin-releasing peptide on food intake in humans, Gastroenterology, 106 (1994) 1168-1173.
43. Gibbs, J., Smith, G.P. and Kirkham, T.C., Gastrin-releasing peptide and satiety, Gastroenterology, 106 (1994) 1374-1376.
44. Flynn, F.W., Fourth ventricular injection of selective bombesin receptor antagonists facilitates feeding in rats, Am. J. Physiol., 264 (1993) R218-R221.