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Some of the altohyrtin macrolides reported in the following papers are assumed to be structurally identical to the spongistatins (i.e. altohyrtin A corresponds to spongistatin 1): (a) Kobayashi, M.; Aoki, S.; Gato, K.; Kitagawa, I. Chem. Pharm. Bull. 1996, 44, 2142.
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Cinachyrolide A, isolated from a sponge of the genus Cinachyra, is assumed to be structurally identical to spongistatin 4: Fusetani, N.; Shinoda, K.; Matsunaga, S. J. Am. Chem. Soc. 1993, 115, 3977.
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note
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15) (cf. 5.12, dd, J = 1.7, 11), 6.90 (2H, d, J = 8.6 Hz, Ar, 7.26 (2H, d, J = 8.6 Hz, Ar).
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22
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Paterson, I.; Goodman, J. M.; Lister, M. A.; Schumann, R. C.; McClure, C. K.; Norcross, R. D. Tetrahedron 1990, 46, 4663.
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85036684389
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note
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iPrMgCl, THF, -20 °C, 1 h; and (iii) MeMgBr, THF, 0 °C → 20 °C, 2 h.
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Paterson, I.; Goodman, J. M.; Isaka, M. Tetrahedron Lett. 1989, 30, 7121.
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