메뉴 건너뛰기




Volumn 49, Issue 10, 1997, Pages 991-998

Effects of meloxicam, compared with other NSAIDs, on cartilage proteoglycan metabolism, synovial prostaglandin E2, and production of interleukins 1, 6 and 8, in human and porcine explants in organ culture

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; INDOMETACIN; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PROSTAGLANDIN E2; PROTEOGLYCAN;

EID: 0030697233     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06030.x     Document Type: Article
Times cited : (56)

References (28)
  • 1
    • 0022342047 scopus 로고
    • The properties of proteoglycan prepared from human articular cartilage by using associative cesium chloride gradients of high and low starting densities
    • Bayliss, M. T., Roughley, P. J. (1985) The properties of proteoglycan prepared from human articular cartilage by using associative cesium chloride gradients of high and low starting densities. Biochem. J. 232: 111-117
    • (1985) Biochem. J. , vol.232 , pp. 111-117
    • Bayliss, M.T.1    Roughley, P.J.2
  • 2
    • 15644368105 scopus 로고
    • Non-steroidal anti-inflammatory drugs and the augmented lipoxygenase pathway: Conceivable impact on joint conditions
    • Rainsford, K. D., Velo, G. P. (eds) Kluwer Academic Publishers, Lancaster
    • Bonta, I. L., Elliott, G. R. (1992) Non-steroidal anti-inflammatory drugs and the augmented lipoxygenase pathway: conceivable impact on joint conditions. In: Rainsford, K. D., Velo, G. P. (eds) Side Effects of Anti-inflammatory Drugs 3. Kluwer Academic Publishers, Lancaster, pp 269-274
    • (1992) Side Effects of Anti-inflammatory Drugs , vol.3 , pp. 269-274
    • Bonta, I.L.1    Elliott, G.R.2
  • 4
    • 0000040320 scopus 로고
    • Transsynovial kinetics of meloxicam
    • abstract 121
    • Degner, F., Heinzel, G., Busch, U. (1994) Transsynovial kinetics of meloxicam. Scand. J. Rheumatol. 23 (Suppl 98): abstract 121
    • (1994) Scand. J. Rheumatol. , vol.23 , Issue.98 SUPPL.
    • Degner, F.1    Heinzel, G.2    Busch, U.3
  • 5
    • 0013567673 scopus 로고
    • NSAIDs and human cartilage metabolism
    • Rainsford, K. D., Velo, G. P. (eds) Kluwer Academic Publishers, Lancaster
    • Dingle, J. T. (1992) NSAIDs and human cartilage metabolism. In: Rainsford, K. D., Velo, G. P. (eds) Side Effects of Anti-inflammatory Drugs 3. Kluwer Academic Publishers, Lancaster, pp 261-268
    • (1992) Side Effects of Anti-inflammatory Drugs , vol.3 , pp. 261-268
    • Dingle, J.T.1
  • 6
    • 0030007321 scopus 로고    scopus 로고
    • Global analysis of gastrointestinal safety of a new NSAID, meloxicam
    • Distel, M., Mueller, C., Bluhmki, E. (1996) Global analysis of gastrointestinal safety of a new NSAID, meloxicam. Inflammopharmacology 4: 71-81
    • (1996) Inflammopharmacology , vol.4 , pp. 71-81
    • Distel, M.1    Mueller, C.2    Bluhmki, E.3
  • 7
    • 0028860983 scopus 로고
    • Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance
    • Engelhardt, G., Homma, D., Schlegel, K., Utzmann, R., Schnitzler, C. (1995) Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance. Inflamm. Res. 44: 423-433
    • (1995) Inflamm. Res. , vol.44 , pp. 423-433
    • Engelhardt, G.1    Homma, D.2    Schlegel, K.3    Utzmann, R.4    Schnitzler, C.5
  • 8
    • 0030030129 scopus 로고    scopus 로고
    • Meloxicam: Influence on arachidonic acid metabolism. In vitro findings-Part I
    • Engelhardt, G., Bgel, R., Schnitzler, C., Utzmann, R. (1996) Meloxicam: influence on arachidonic acid metabolism. In vitro findings-Part I. Biochem. Pharmacol. 51: 21-28
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 21-28
    • Engelhardt, G.1    Bgel, R.2    Schnitzler, C.3    Utzmann, R.4
  • 9
    • 0019914963 scopus 로고
    • A direct spectrophotometric microassay for sulphated glycosaminoglycan in articular cartilage cultures
    • Farndale, R. W., Savers, C. A., Barrett, A. J. (1982) A direct spectrophotometric microassay for sulphated glycosaminoglycan in articular cartilage cultures. Connect. Tissue Res. 9: 247-248
    • (1982) Connect. Tissue Res. , vol.9 , pp. 247-248
    • Farndale, R.W.1    Savers, C.A.2    Barrett, A.J.3
  • 10
    • 0027304433 scopus 로고
    • Interleukin-6 in autoimmune diseases. Role of IL-6 in physiology and pathology of immune defence
    • Graeve, L., Baumarm, M., Heinrich, P. C. (1993) Interleukin-6 in autoimmune diseases. Role of IL-6 in physiology and pathology of immune defence. Clin. Invest. 71: 664-671
    • (1993) Clin. Invest. , vol.71 , pp. 664-671
    • Graeve, L.1    Baumarm, M.2    Heinrich, P.C.3
  • 12
    • 0024406352 scopus 로고
    • Simple, sensitive and specific bioassay of interleukin-1
    • Hopkins, S. J., Humphreys, M. (1989) Simple, sensitive and specific bioassay of interleukin-1. J. Immunol. Methods 120: 271-276
    • (1989) J. Immunol. Methods , vol.120 , pp. 271-276
    • Hopkins, S.J.1    Humphreys, M.2
  • 13
    • 15644362862 scopus 로고
    • Removal of inhibitory activity and determination of biologically active interleukin-1 in biological fluids
    • Dinarell, C. A., Kluger, M. J., Powanda, M. C., Oppenheim, J. J. (eds) Wiley-Liss, New York
    • Hopkins, S. J., Holt, I., Humphreys, M. (1990) Removal of inhibitory activity and determination of biologically active interleukin-1 in biological fluids. In: Dinarell, C. A., Kluger, M. J., Powanda, M. C., Oppenheim, J. J. (eds) The Physiological and Pathological Effects of Cytokines. Wiley-Liss, New York, pp 7-12
    • (1990) The Physiological and Pathological Effects of Cytokines , pp. 7-12
    • Hopkins, S.J.1    Holt, I.2    Humphreys, M.3
  • 17
    • 0021920409 scopus 로고
    • Kinetics of extraction of proteoglycans from human cartilage
    • Pottenger, L. A., Webb, J. E., Lyon, N. B. (1985) Kinetics of extraction of proteoglycans from human cartilage. Arthritis Rheum. 28: 323-330
    • (1985) Arthritis Rheum. , vol.28 , pp. 323-330
    • Pottenger, L.A.1    Webb, J.E.2    Lyon, N.B.3
  • 18
    • 0038597868 scopus 로고    scopus 로고
    • Mode of action, uses, and side effects of anti-inflammatory drugs
    • Rainsford, K. D. (ed.) CRC Press, Boca Raton
    • Rainsford, K. D. (1996) Mode of action, uses, and side effects of anti-inflammatory drugs. In: Rainsford, K. D. (ed.) Advances in Anti-Rheumatic Therapy. CRC Press, Boca Raton, pp 59-111
    • (1996) Advances in Anti-Rheumatic Therapy , pp. 59-111
    • Rainsford, K.D.1
  • 19
    • 0024391719 scopus 로고
    • Comparative effects of azapropazone on cellular events at inflamed sites. Influence on joint pathology in arthritic rats, leucocyte superoxide and eicosanoid production, platelet aggregation, synthesis of cartilage proteoglycans, synovial production and actions of interleukin-1 in cartilage resorption correlated with drug uptake into cartilage in-vitro
    • Rainsford, K. D., Davies, A., Mundy, L., Ginsburg, I. (1989) Comparative effects of azapropazone on cellular events at inflamed sites. Influence on joint pathology in arthritic rats, leucocyte superoxide and eicosanoid production, platelet aggregation, synthesis of cartilage proteoglycans, synovial production and actions of interleukin-1 in cartilage resorption correlated with drug uptake into cartilage in-vitro. J. Pharm. Pharmacol. 41: 322-330
    • (1989) J. Pharm. Pharmacol. , vol.41 , pp. 322-330
    • Rainsford, K.D.1    Davies, A.2    Mundy, L.3    Ginsburg, I.4
  • 20
    • 8044256292 scopus 로고
    • Effects of NSAIDs on cartilage proteoglycan and synovial prostaglandin metabolism in relation to joint deterioration in osteoarthritis
    • Blint, G., Gmr, L., Hodinka, L. (eds) State of the Art, Elsevier, Amsterdam
    • Rainsford, K. D., Rashad, S. Y., Revell, P. A., Low, F. M., Hemingway, A. P., Walker, F. S., Johnson, D., Stetsko, P., Ying, C., Smith, F. (1992) Effects of NSAIDs on cartilage proteoglycan and synovial prostaglandin metabolism in relation to joint deterioration in osteoarthritis In: Blint, G., Gmr, L., Hodinka, L. (eds) Rheumatology, State of the Art, Elsevier, Amsterdam, pp 177-183
    • (1992) Rheumatology , pp. 177-183
    • Rainsford, K.D.1    Rashad, S.Y.2    Revell, P.A.3    Low, F.M.4    Hemingway, A.P.5    Walker, F.S.6    Johnson, D.7    Stetsko, P.8    Ying, C.9    Smith, F.10
  • 21
    • 0029918370 scopus 로고    scopus 로고
    • Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: Comparison with DL-1 synthesis inhibitors
    • Rainsford, K. D., Ying, C., Smith, F. (1996) Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with DL-1 synthesis inhibitors. J. Pharm. Pharmacol. 48: 45-50
    • (1996) J. Pharm. Pharmacol. , vol.48 , pp. 45-50
    • Rainsford, K.D.1    Ying, C.2    Smith, F.3
  • 22
    • 0031050198 scopus 로고    scopus 로고
    • A comparison between the effects of meloxicam and other NSAIDs on the production of oxyradicals by human polymorphonuclear leucocytes
    • Rainsford, K. D., Ginsburg, I., Gadd, S. J. (1997) A comparison between the effects of meloxicam and other NSAIDs on the production of oxyradicals by human polymorphonuclear leucocytes. Inflammopharmacology 5: 9-19
    • (1997) Inflammopharmacology , vol.5 , pp. 9-19
    • Rainsford, K.D.1    Ginsburg, I.2    Gadd, S.J.3
  • 23
    • 0024413965 scopus 로고
    • Effects of non-steroidal anti-inflammatory drugs on the course osteoarthritis
    • Rashad, S., Revell, P., Hemingway, A., Low, F., Rainsford, K., Walker, F. (1989) Effects of non-steroidal anti-inflammatory drugs on the course osteoarthritis. Lancet ii: 519-522
    • (1989) Lancet , vol.2 , pp. 519-522
    • Rashad, S.1    Revell, P.2    Hemingway, A.3    Low, F.4    Rainsford, K.5    Walker, F.6
  • 24
    • 0025046995 scopus 로고
    • Interleukin-6 enhances the production of tissue inhibitor of metalloproteinases TIMP but not that of matrix metalloproteinases by human fibroblasts
    • Sato, T., Ito, A., Mon, Y. (1990) Interleukin-6 enhances the production of tissue inhibitor of metalloproteinases (TIMP but not that of matrix metalloproteinases by human fibroblasts. Biochem. Biophys. Res. Commun. 170: 824-829
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 824-829
    • Sato, T.1    Ito, A.2    Mon, Y.3
  • 25
    • 0028926813 scopus 로고
    • New insights into the mode of action of anti-inflammatory drugs
    • Vane, J. R., Botting, R. M. (1995) New insights into the mode of action of anti-inflammatory drugs. Inflamm. Res. 44: 1-10
    • (1995) Inflamm. Res. , vol.44 , pp. 1-10
    • Vane, J.R.1    Botting, R.M.2
  • 26
    • 0017333913 scopus 로고
    • Synthesis of cartilage-specific proteoglycan by suspension cultures of adult chondrocytes
    • Weibkin, O. W., Muir, H. (1977) Synthesis of cartilage-specific proteoglycan by suspension cultures of adult chondrocytes. Biochem. J. 164: 269-272
    • (1977) Biochem. J. , vol.164 , pp. 269-272
    • Weibkin, O.W.1    Muir, H.2
  • 27
    • 0001692304 scopus 로고
    • The acute phase response
    • Whicher, J. T., Evans, S. W. (eds) Kluwer Academic Publishers, Dordrecht
    • Whicher, J. T., Westacott, C. I. (1992) The acute phase response. In: Whicher, J. T., Evans, S. W. (eds) Biochemistry of Inflammation. Kluwer Academic Publishers, Dordrecht, pp 243-269
    • (1992) Biochemistry of Inflammation , pp. 243-269
    • Whicher, J.T.1    Westacott, C.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.