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Volumn 10, Issue 1-2, 1997, Pages 87-99

Antisense agrin cDNA transfection blocks neuroblastoma cell-induced acetylcholine receptor aggregation when co-cultured with myotubes

Author keywords

Antisense; Nerve muscle co culture; Neuroblastoma; Neuromuscular junction; Synaptogenesis

Indexed keywords

AGRIN; CHOLINERGIC RECEPTOR; COMPLEMENTARY DNA;

EID: 0030696922     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1997.0637     Document Type: Article
Times cited : (21)

References (45)
  • 1
    • 0019436012 scopus 로고
    • Partial purification of a neuronal factor which increase acetylcholine receptor aggregation on cultured muscle cells
    • Bauer, H. C., Daniels, M. P., Pudimat, P. A., Jacques, L., Sugiyama, H., and Christian, C. N. (1981). Partial purification of a neuronal factor which increase acetylcholine receptor aggregation on cultured muscle cells. Brain Res. 209: 395-404.
    • (1981) Brain Res. , vol.209 , pp. 395-404
    • Bauer, H.C.1    Daniels, M.P.2    Pudimat, P.A.3    Jacques, L.4    Sugiyama, H.5    Christian, C.N.6
  • 2
    • 0028914466 scopus 로고
    • The role of agrin in synapse formation
    • Bowe, M. A., and Fallon, J. R. (1995). The role of agrin in synapse formation. Annu. Rev. Neurosci. 18: 443-462.
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 443-462
    • Bowe, M.A.1    Fallon, J.R.2
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 4
    • 0021679630 scopus 로고
    • Three cholinergic neuroblastoma hybrid cell lines that form few synapses on myotubes are deficient in acetylcholine receptor aggregation molecules and large dense core vesicles
    • Busis, N. A., Daniels, M. P., Bauer, H. C., Pudimat, P. A., Sonderegger, P., Schaffner, A. E., and Nirenberg, M. (1984). Three cholinergic neuroblastoma hybrid cell lines that form few synapses on myotubes are deficient in acetylcholine receptor aggregation molecules and large dense core vesicles. Brain Res. 324: 201-210.
    • (1984) Brain Res. , vol.324 , pp. 201-210
    • Busis, N.A.1    Daniels, M.P.2    Bauer, H.C.3    Pudimat, P.A.4    Sonderegger, P.5    Schaffner, A.E.6    Nirenberg, M.7
  • 5
    • 0029609816 scopus 로고
    • Agrin is a differentiation-inducing "stop signal" for motoneurons in vitro
    • Campagna, J. A., Ruegg, M. A., and Bixby, J. L. (1995). Agrin is a differentiation-inducing "stop signal" for motoneurons in vitro. Neuron 15: 1365-1374.
    • (1995) Neuron , vol.15 , pp. 1365-1374
    • Campagna, J.A.1    Ruegg, M.A.2    Bixby, J.L.3
  • 6
    • 0025786165 scopus 로고
    • Agrin mediates cell contact-induced acetylcholine receptor clustering
    • Campanelli, J. T., Hoch, W., Rupp, F., Kreiner, T., and Scheller, R. H. (1991). Agrin mediates cell contact-induced acetylcholine receptor clustering. Cell 67: 909-916.
    • (1991) Cell , vol.67 , pp. 909-916
    • Campanelli, J.T.1    Hoch, W.2    Rupp, F.3    Kreiner, T.4    Scheller, R.H.5
  • 7
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-choroform extraction
    • Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-choroform extraction. Anal. Biochem. 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 8
    • 0018154832 scopus 로고
    • A factor from neurons increases the number of acetylcholine receptor aggregates on cultured muscle cells
    • Christian, C. N., Daniels, M. P., Sugiyama, H., Vogel, Z., Jacques, L., and Nelson, P. G. (1978). A factor from neurons increases the number of acetylcholine receptor aggregates on cultured muscle cells. Proc. Natl. Acad. Sci. USA 75: 4011-4015.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 4011-4015
    • Christian, C.N.1    Daniels, M.P.2    Sugiyama, H.3    Vogel, Z.4    Jacques, L.5    Nelson, P.G.6
  • 9
    • 0026665716 scopus 로고
    • Early appearance of and neuronal contribution to agrin-like molecules at embryonic frog nerve-muscle synapses formed in culture
    • Cohen, M. W., and Godfrey, E. W. (1992). Early appearance of and neuronal contribution to agrin-like molecules at embryonic frog nerve-muscle synapses formed in culture. J. Neurosci. 12: 2982-2992.
    • (1992) J. Neurosci. , vol.12 , pp. 2982-2992
    • Cohen, M.W.1    Godfrey, E.W.2
  • 10
    • 0024522577 scopus 로고
    • Agrin related molecules are concentrated at acetylcholine receptor cluster in normal and aneural developing muscle
    • Fallon, J. R., and Gelfman, C. E. (1989). Agrin related molecules are concentrated at acetylcholine receptor cluster in normal and aneural developing muscle. J. Cell Biol. 108: 1527-1535.
    • (1989) J. Cell Biol. , vol.108 , pp. 1527-1535
    • Fallon, J.R.1    Gelfman, C.E.2
  • 11
    • 0026652948 scopus 로고
    • RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes
    • Ferns, M., Hock, W., Campanelli, J. T., Rupp, F., Hall, Z. W., and Scheller, R. H. (1992). RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes. Neuron 8: 1079-1086.
    • (1992) Neuron , vol.8 , pp. 1079-1086
    • Ferns, M.1    Hock, W.2    Campanelli, J.T.3    Rupp, F.4    Hall, Z.W.5    Scheller, R.H.6
  • 12
    • 0027517961 scopus 로고
    • The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans
    • Ferns, M., Campanelli, J. T., Hoch, W., Scheller, R. H., and Hall, Z. W. (1993). The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans. Neuron 11: 491-502.
    • (1993) Neuron , vol.11 , pp. 491-502
    • Ferns, M.1    Campanelli, J.T.2    Hoch, W.3    Scheller, R.H.4    Hall, Z.W.5
  • 13
    • 0028897167 scopus 로고
    • Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site
    • Gesemann, M., Denzer, A. J., and Ruegg, M. A. (1995). Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site. J. Cell Biol. 128: 625-636.
    • (1995) J. Cell Biol. , vol.128 , pp. 625-636
    • Gesemann, M.1    Denzer, A.J.2    Ruegg, M.A.3
  • 15
    • 0023937264 scopus 로고
    • Acetylcholine receptor-aggregating proteins are associated with the extracellular matrix of many tissues in Torpedo
    • Godfrey, E. W., Dietz, M. E., Morstad, A. L., Wallskog, P. A., and Yorde, D. E. (1988). Acetylcholine receptor-aggregating proteins are associated with the extracellular matrix of many tissues in Torpedo. J. Cell Biol. 106: 1263-1272.
    • (1988) J. Cell Biol. , vol.106 , pp. 1263-1272
    • Godfrey, E.W.1    Dietz, M.E.2    Morstad, A.L.3    Wallskog, P.A.4    Yorde, D.E.5
  • 16
    • 0025773938 scopus 로고
    • Comparison of agrin-like proteins from the extracellular matrix of chicken kidney and muscle with neural agrin, a synapse organizing protein
    • Godfrey, E. W. (1991). Comparison of agrin-like proteins from the extracellular matrix of chicken kidney and muscle with neural agrin, a synapse organizing protein. Exp. Cell Res. 195: 99-109.
    • (1991) Exp. Cell Res. , vol.195 , pp. 99-109
    • Godfrey, E.W.1
  • 17
    • 0027480289 scopus 로고
    • Synaptic structure and development: The neuromuscular junction
    • Hall, Z. W., and Sanes, J. R. (1993). Synaptic structure and development: The neuromuscular junction. Cell72/Neuron 10(Suppl.): 99-121.
    • (1993) Cell72/Neuron , vol.10 , Issue.SUPPL. , pp. 99-121
    • Hall, Z.W.1    Sanes, J.R.2
  • 18
    • 0027369903 scopus 로고    scopus 로고
    • Developmental regulation of highly active alternatively spliced forms of agrin
    • Hoch, W., Ferns, M., Campanelli, J. T., Hall, Z. W., and Scheller, R. H. (1993). Developmental regulation of highly active alternatively spliced forms of agrin. Neuron 11: 479-490.
    • Neuron , vol.11 , pp. 479-490
    • Hoch, W.1    Ferns, M.2    Campanelli, J.T.3    Hall, Z.W.4    Scheller, R.H.5
  • 19
    • 0030032097 scopus 로고    scopus 로고
    • The developing avian retina expresses agrin isoforms during synaptogenesis
    • Kröger, S., Horton, S. E., and Honig, L. S. (1996). The developing avian retina expresses agrin isoforms during synaptogenesis. J. Neurobiol. 29: 165-182.
    • (1996) J. Neurobiol. , vol.29 , pp. 165-182
    • Kröger, S.1    Horton, S.E.2    Honig, L.S.3
  • 20
    • 0028230678 scopus 로고
    • Distribution of agrin messenger-RNAs in the chick embryo nervous system
    • Ma, E., Morgan, R., and Godfrey, E. W. (1994). Distribution of agrin messenger-RNAs in the chick embryo nervous system. J. Neurosci. 14: 2943-2952.
    • (1994) J. Neurosci. , vol.14 , pp. 2943-2952
    • Ma, E.1    Morgan, R.2    Godfrey, E.W.3
  • 21
    • 0023723324 scopus 로고
    • Motor neurons contain agrin-like molecules
    • Magill-Solc, C., and McMahan, U. J. (1988). Motor neurons contain agrin-like molecules. J. Cell Biol. 107: 1825-1833.
    • (1988) J. Cell Biol. , vol.107 , pp. 1825-1833
    • Magill-Solc, C.1    McMahan, U.J.2
  • 25
    • 0028344867 scopus 로고
    • Localization and alternative splicing of agrin mRNA in adult rat brain: Transcript encoding isoforms that aggregate acetylcholine receptors are not restricted to cholinergic regions
    • O'Connor, L. T., Lauterborn, J. C., Gall, C. M., and Smith, M. A. (1994). Localization and alternative splicing of agrin mRNA in adult rat brain: Transcript encoding isoforms that aggregate acetylcholine receptors are not restricted to cholinergic regions. J. Neurosci. 14: 1141-1152.
    • (1994) J. Neurosci. , vol.14 , pp. 1141-1152
    • O'Connor, L.T.1    Lauterborn, J.C.2    Gall, C.M.3    Smith, M.A.4
  • 26
    • 0030689638 scopus 로고    scopus 로고
    • Agrin-deficient myotube retains its acetylcholine receptor aggregation ability when challenged with agrin
    • in press
    • Pun, S., Ng, Y.P., Yang, J.F., Ip, N.Y., and Tsim, K.W.K. (1997). Agrin-deficient myotube retains its acetylcholine receptor aggregation ability when challenged with agrin. J. Neurochem., in press.
    • (1997) J. Neurochem.
    • Pun, S.1    Ng, Y.P.2    Yang, J.F.3    Ip, N.Y.4    Tsim, K.W.K.5
  • 27
    • 0010983530 scopus 로고
    • Agrin from NG108-15 induces acetylcholine receptor aggregation on primary rat myotube cultures
    • Pun, S., So, K. L., and Tsim, K. W. K. (1995). Agrin from NG108-15 induces acetylcholine receptor aggregation on primary rat myotube cultures. Soc. Neurosci. Abstr. 21: 700.6.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 7006
    • Pun, S.1    So, K.L.2    Tsim, K.W.K.3
  • 28
    • 0028972373 scopus 로고
    • Truncated form of pro-acetylcholine receptor-inducing activity (ARIA) induces AChR α-subunit but not AChE transcripts in cultured chick myotubes
    • Pun, S., and Tsim, K. W. K. (1995). Truncated form of pro-acetylcholine receptor-inducing activity (ARIA) induces AChR α-subunit but not AChE transcripts in cultured chick myotubes. Neurosci. Lett. 198: 107-110.
    • (1995) Neurosci. Lett. , vol.198 , pp. 107-110
    • Pun, S.1    Tsim, K.W.K.2
  • 29
    • 0023581595 scopus 로고
    • Agrin-like molecules at synaptic sites in normal, denervated, and damaged skeletal muscles
    • Reist, N. E., Magill, C., and McMahan, U. J. (1987). Agrin-like molecules at synaptic sites in normal, denervated, and damaged skeletal muscles. J. Cell Biol. 105: 2457-2469.
    • (1987) J. Cell Biol. , vol.105 , pp. 2457-2469
    • Reist, N.E.1    Magill, C.2    McMahan, U.J.3
  • 30
    • 0026633248 scopus 로고
    • Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions
    • Reist, N. E., Werle, M. J., and McMahan, U. J. (1992). Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions. Neuron 8: 865-868.
    • (1992) Neuron , vol.8 , pp. 865-868
    • Reist, N.E.1    Werle, M.J.2    McMahan, U.J.3
  • 31
    • 0022135418 scopus 로고
    • 2+ mediates changes in acetylcholinesterase and acetylcholine receptor caused by muscle contraction
    • 2+ mediates changes in acetylcholinesterase and acetylcholine receptor caused by muscle contraction. Proc. Natl. Acad. Sci. USA 82: 7121-7125.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 7121-7125
    • Rubin, L.L.1
  • 32
    • 0026583243 scopus 로고
    • The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
    • Ruegg, M. A., Tsim, K. W. K., Horton, S. E., Kröger, S., Escher, G., Gensch, E. M., and McMahan, U. J. (1992). The agrin gene codes for a family of basal lamina proteins that differ in function and distribution. Neuron 8: 691-699.
    • (1992) Neuron , vol.8 , pp. 691-699
    • Ruegg, M.A.1    Tsim, K.W.K.2    Horton, S.E.3    Kröger, S.4    Escher, G.5    Gensch, E.M.6    McMahan, U.J.7
  • 36
    • 0028230010 scopus 로고
    • Cell-specific regulation of agrin RNA splicing in the chick ciliary ganglion
    • Smith, M. A., and O'Dowd, D. K. (1994). Cell-specific regulation of agrin RNA splicing in the chick ciliary ganglion. Neuron 12: 795-804.
    • (1994) Neuron , vol.12 , pp. 795-804
    • Smith, M.A.1    O'Dowd, D.K.2
  • 37
    • 0010989671 scopus 로고
    • NGF dependent regulation of agrin gene expression in PC12 cells
    • Smith, M. A., O'Connor, L. T., Fanger, G., and Maue, R. A. (1995). NGF dependent regulation of agrin gene expression in PC12 cells. Soc. Neurosci. Abstr. 21: 700.8.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 700
    • Smith, M.A.1    O'Connor, L.T.2    Fanger, G.3    Maue, R.A.4
  • 38
    • 0030034404 scopus 로고    scopus 로고
    • Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity
    • So, K. L., Pun, S., Wan, D. C. C., and Tsim, K. W. K. (1996). Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity. FEBS Lett. 379: 63-68.
    • (1996) FEBS Lett. , vol.379 , pp. 63-68
    • So, K.L.1    Pun, S.2    Wan, D.C.C.3    Tsim, K.W.K.4
  • 39
    • 0027200561 scopus 로고
    • Developmental expression and alternative splicing of chick agrin RNA
    • Thomas, W. S., O'Dowd, D. K., and Smith, M. A. (1993). Developmental expression and alternative splicing of chick agrin RNA. Dev. Biol. 158: 523-535.
    • (1993) Dev. Biol. , vol.158 , pp. 523-535
    • Thomas, W.S.1    O'Dowd, D.K.2    Smith, M.A.3
  • 40
    • 0028813382 scopus 로고
    • Agrin is a heparan sulfate proteoglycan
    • Tsen, G., Halfter, W., Kröger, S., and Cole, G. K. (1995). Agrin is a heparan sulfate proteoglycan. J. Biol. Chem. 270: 3392-3399.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3392-3399
    • Tsen, G.1    Halfter, W.2    Kröger, S.3    Cole, G.K.4
  • 42
    • 0022472566 scopus 로고
    • Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase and butyrylcholinesterase on cultured myotubes
    • Wallace, B. G. (1986). Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase and butyrylcholinesterase on cultured myotubes. J. Cell Biol. 102: 783-794.
    • (1986) J. Cell Biol. , vol.102 , pp. 783-794
    • Wallace, B.G.1
  • 43
    • 0026684767 scopus 로고
    • Mechanism of agrin-induced acetylcholine receptor aggregation
    • Wallace, B. G. (1992). Mechanism of agrin-induced acetylcholine receptor aggregation. J. Neurobiol. 23: 592-604.
    • (1992) J. Neurobiol. , vol.23 , pp. 592-604
    • Wallace, B.G.1
  • 44
    • 0028260234 scopus 로고
    • Staurosporine inhibits agrin-induced acetylcholine receptor phosphorylation and aggregation
    • Wallace, B. G. (1994). Staurosporine inhibits agrin-induced acetylcholine receptor phosphorylation and aggregation. J. Cell Biol. 125: 661-668.
    • (1994) J. Cell Biol. , vol.125 , pp. 661-668
    • Wallace, B.G.1
  • 45
    • 0025779156 scopus 로고
    • Agrin induces phosphorylation of the nicotinic acetylcholine receptor
    • Wallace, B. G., Qu, Z., and Huganir, R. L. (1991). Agrin induces phosphorylation of the nicotinic acetylcholine receptor. Neuron 6: 869-878.
    • (1991) Neuron , vol.6 , pp. 869-878
    • Wallace, B.G.1    Qu, Z.2    Huganir, R.L.3


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