Resolution of a citric acid derivative: Synthesis of (R)-(-)-homocitric acid-γ-lactone

Tetrahedron Asymmetry

Volumn 8, Issue 20, 1997, Pages 3379-3382

  Ancliff, Rachael A ^a   Russell, Andrew T ^b   Sanderson, Adam J ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF SALFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CITRIC ACID; HOMOCITRIC ACID GAMMA LACTONE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CRYSTALLIZATION; ENANTIOMER; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS;

EID: 0030693639     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(97)00435-7     Document Type: Article

References (14)

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9. A small amount of ring opening to give the ethyl ester 10 was found to accompany this treatment but 10 remained in the mother liquor. figure presented
10. Basification of the aqueous layer with sodium hydroxide allows the recovery and recycling of the α-methylbenzylamine.
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