Alkylation of a catalytic aspartate group of the SIV protease by an epoxide inhibitor

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 11, 1997, Pages 2019-2027

  Caldera, Patricia S ^a   Yu, Zhonghua ^a   Knegtel, Ronald M A ^a   McPhee, Fiona ^a   Burlingame, Alma L ^a   Craik, Charles S ^a   Kuntz, Irwin D ^a   De Montellano, Paul R Ortiz ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR;

ALKYLATION; ARTICLE; CATALYSIS; ENZYME INACTIVATION; ENZYME MODIFICATION; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; SIMIAN IMMUNODEFICIENCY VIRUS;

ALKYLATION; ANTIVIRAL AGENTS; ASPARTIC ACID; ASPARTIC ENDOPEPTIDASES; CATALYSIS; ENZYME ACTIVATION; EPOXY COMPOUNDS; MASS SPECTROMETRY; MODELS, MOLECULAR; PROTEASE INHIBITORS; SIMIAN IMMUNODEFICIENCY VIRUS;

SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0030687592     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00131-4     Document Type: Article

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