Moment analysis of intestinal first-pass metabolism by portal-systemic concentration difference in single conscious rat using 5'-deoxy-5- fluorouridine and 5-fluorouracil as model drug system

Journal of Pharmaceutical Sciences

Volumn 86, Issue 11, 1997, Pages 1269-1272

  Sawai, Yoneichi ^a   Yamaoka, Kiyoshi ^a   Takemura, Arisa ^a   Nakagawa, Terumichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG METABOLISM; FIRST PASS EFFECT; INTESTINE ABSORPTION; INTESTINE MUCOSA; NONHUMAN; PORTAL VEIN; RAT;

EID: 0030686441     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js970103o     Document Type: Article

References (27)

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