Calcitonin gene-related peptide (CGRP), a potent regulator of biliary flow

Neurogastroenterology and Motility

Volumn 9, Issue 4, 1997, Pages 215-220

  Rasmussen, T N ^a   Harling, H ^b   Rehfeld, J F ^a   Holst, J J ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Biliary motility; Gastrointestinal motility; Neuropeptides; Sphincter of Oddi

Indexed keywords

ATROPINE; CALCITONIN GENE RELATED PEPTIDE; CHOLECYSTOKININ;

ANIMAL EXPERIMENT; ARTICLE; BILE FLOW; CHOLINERGIC SYSTEM; CONTROLLED STUDY; GALLBLADDER; GALLBLADDER CONTRACTION; HEPATOBILIARY SYSTEM; HORMONE RELEASE; NONHUMAN; ODDI SPHINCTER; PRIORITY JOURNAL; SWINE;

EID: 0030671450     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.1997.d01-57.x     Document Type: Article

References (31)

1. Funch-Jensen P. Sphincter of Oddi motility. Acta Chir Scand 1990 (Suppl. 553).
2. Dahlstrand C. The vagal nerves and peptides in the control of extrahepatic biliary motility. Acta Physiol Scand 1990; 139: (Suppl. 589).
3. Wiley JW, O'Dorisio TM, Owyang C. Vasoactive intestinal polypeptide mediates cholecystokinin-induced relaxation of the sphincter of Oddi. J Clin Invest 1988; 81: 1920-4.
4. Becker JM, Moody FG, Zinsmeister AR. Effect of gastrointestinal hormones on the biliary sphincter of the opossum. Gastroenterology 1982; 82: 1300-7.
5. Sarles JC, Delecourt P, Castello H, et al. Action of gastrointestinal hormones on the myoelectrical activity of the sphincter of Oddi in living rabbits. Regul Pept 1981; 2: 114-24.
6. Lin TM, Spray GF. Effect of pentagastrin, cholecystokinin, caerulein and glucagon on the cholodochal resistance and bile flow of dogs. Gastroenterology 1969; 56: 1178.
7. Behar J, Biancani P. Effect of cholecystokinin and octapeptide of cholecystokinin on the feline sphincter of Oddi and gallbladder. J Clin Invest 1980; 66: 1231-9.
8. Sand J, Tainio H, Nordback I. Neuropeptides in pig sphincter of Oddi, bile duct, gallbladder, and duodenum. Dig Dis Sci 1993; 4: 694-700.
9. Amara SG, Jonas V, Rosenfeld MG, Ong ES, Evans RM. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature 1982; 298: 240-4.
10. Rosenfeld MG, Mermod J-J, Amara SG, et al. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 1983; 304: 129-35.
11. Amara SG, Arriza JL, Leff SE, Swanson LW, Evans RM, Rosenfeld MG. Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. Science 1985; 229: 1094-7.
12. Morris HR, Panico M, Etienne T, Tippins J, Girgis SI, MacIntyre I. Isolation and characterization of human calcitonin gene-related peptide. Nature 1984; 308: 746-8.
13. Rasmussen TN, Bersani M, Johnsen AH, Kofod H, Holst JJ. Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments. Peptides 1994; 15: 89-94.
14. Hashimoto T, Poston GJ, Greeley GH, Thompson JC. Calcitonin gene-related peptide inhibits gallbladder contractility. Surgery 1988; 104: 419-23.
15. Maggi CA, Santicioli P, Renzi D, Patacchini R, Surrenti C, Meli A. Release of substance P- and calcitonin gene-related peptide-like immunoreactivity and motor response of the isolated guinea pig gallbladder to capsaicin. Gastroenterology 1989; 96: 1093-101.
16. Kline LW, Kaneko T, Benishin G, Pang PKT. Calcitonin gene-related peptide: an inhibitor of guinea pig gallbladder contraction. Can J Physiol Pharmacol 1991; 69: 1149-54.
17. Muller EL, Lewinski MA, Pitt HA. The cholecysto-sphincter of Oddi reflex. J Surg Res 1984; 36: 377-83.
18. Webb TA, Lillemoe KD, Pitt HA. The gastro-sphincter of Oddi reflex. Am J Surg 1988; 155: 193-8.
19. Rasmussen TN, Bersani M, Schmidt P, et al. Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas. Pancreas.
20. Muller EL, Grace PA, Conter RL, Roslyn JJ, Pitt HA. Influence of motilin and cholecystokinin on sphincter of Oddi and duodenal motility. Am J Physiol 1987; 16: 253, G679-83.
21. Cantor P, Rehfeld JF. Cholecystokinin in pig plasma: release of components devoid of a bioactivc COOH-terminus. Am J Physiol 1989; 256: G53-61.
22. Toouli J. Sphincter of Oddi motility. Br J Surg 1984; 71: 251-6.
23. Grace PA, Poston GJ, Williamson RCN. Biliary motility. Gut 1990; 31: 571-82.
24. Sternini C, Reeve JR, Brecha N. Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats. Gastroenterology 1987; 93: 852-62.
25. Belai A, Burnstock G. Selective damage of intrinsic calcitonin gene-related peptide-like immunoreactive enteric nerve fibers in streptozotocin-induced diabetic rats. Gastroenterology 1987; 92: 730-4.
26. Bartho L, Petho G, Antal A, Holzer P, Szolcsanyi J. Two types of relaxation due to capsaicin in the guinea pig isolated ileum. Neurosci Lett 1987; 81: 146-50.
27. Maggi CA, Manzini S, Giuliani S, Santicioli P, Meli A. Calcitonin gene-related peptide activates non-adrenergic non-cholinergic relaxation of the rat isolated duodenum. J Pharm Pharmacol 1987; 39: 327-8.
28. Holzer P. Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. Neurosci 1988; 24: 739-68.
29. Bartho L, Lembeck F, Holzer P. Calcitonin gene-related peptide is a potent relaxant of intestinal muscle. Eur J Pharmacol 1987; 135: 449-51.
30. Rasmussen TN, Gregersen H, Harling H, Holst JJ. Calcitonin gene-related peptide (CGRP): effect on contractile activity and luminal cross-sectional area in the isolated perfused porcine ileum. Scand J Gastroenterol 1992; 36: 345-58.
31. Lenz HJ, Zimmerman FG, Messmer B. Regulation of canine gallbladder motility by brain peptides. Gastroenterology 1993; 104: 1678-85.