Development of obesity and insulin resistance in the Israeli sand rat (Psammomys obesus) does leptin play a role?

Annals of the New York Academy of Sciences

Volumn 827, Issue , 1997, Pages 50-63

  Collier, G R ^a   De Silva, A ^a   Sanigorski, A ^a   Walder, K ^a   Yamamoto, A ^b   Zimmet, P ^c  

^a DEAKIN UNIVERSITY   (Australia)

^b SHIZUOKA UNIVERSITY   (Japan)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; GLUCOSE; HORMONE RECEPTOR; INSULIN; LEPTIN; LEPTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; FOOD INTAKE; GENE MUTATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; RAT;

ANIMALIA; PSAMMOMYS OBESUS;

EID: 0030670427     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb51821.x     Document Type: Article

References (41)

1. SHAFRIR, E. & A. GUTMAN. 1993. Psammomys obesus of the Jerusalem colony: a model for nutritionally induced, non-insulin-dependent diabetes. J. Basic Clin. Physiol. Pharmacol. 4: 83-99.
2. KALDERON, B., A. GUTMAN, E. LEVY, E. SHAFRIR & J. H. ADLER. 1986. Characterization of stages of development of obesity-diabetes syndrome in sand rat (Psammomys obesus). Diabetes 35: 717-724.
3. BARNETT, M., G. R. COLLIER, F. M. COLLIER, P. ZIMMET & K. O'DEA. 1994. A cross-sectional and short-term longitudinal characterization of NIDDM in Psammomys obesus. Diabetologia 37: 671-676.
4. BARNETT, M., G. R. COLLIER, P. ZIMMET & K. O'DEA. 1995. Energy intake with respect to the development of diabetes mellitus in Psammomys obesus. Diabetes Nutr. Metab. 8:42-47.
5. HABITO, R., M. BARNETT, A. YAMAMOTO, D. CAMERON-SMITH, K. O'DEA, P. ZIMMET & G. R. COLLIER. 1995. Basal glucose turnover in Psammomys obesus: an animal model of type 2 (non-insulin-dependent) diabetes mellitus. Acta Diabetol. 32: 187-192.
6. BARNETT, M., R. HABITO, D. CAMERON-SMITH, A. YAMAMOTO & G. R. COLLIER. 1996. The effect of inhibiting fatty acid oxidation on basal glucose metabolism in Psammomys obesus. Horm. Metab. Res. 28: 165-170.
7. BARNETT, M., G. R. COLLIER, P. ZIMMET & K. O'DEA. 1994. The effect of restricting energy intake on diabetes in Psammomys obesus. Int. J. Obes. 18: 789-794.
8. DEFRONZO, R. A. 1988. The triumvirate: b-cell, muscle, liver-a collusion responsible for NIDDM. Diabetes 37: 667-687.
9. REAVEN, G. M. 1988. Role of insulin resistance in human disease. Diabetes 37: 1595-1607.
10. ZIMMET, P. Z. 1992. Challenges in diabetes epidemiology-from west to the rest. Diabetes Care 15: 232-247.
11. KENNEDY, G. 1953. The role of depot fat in the hypothalamic control of food intake in the rat. Proc. R. Soc. Lond. 140: 578-592.
12. COLEMAN, D. L. 1978. Obesity and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14: 141-148.
13. COLEMAN, D. L. 1973. Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 9: 294-298.
14. ZHANG, Y, R. PROENCA, M. MAFFEI, M. BARONE, L. LEOPOLD & J. M. FRIEDMAN. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432.
15. HALAAS, J. L., K. S. GAJIWALA, M. MAFFEI, S. L. COHEN, B. T. CHAIT, D. RABINOWITZ, R. L. LALLONE, S. K. BURLEY & J. M. FRIEDMAN. 1995. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269: 543-546.
16. CAMPFIELD, L. A., F. J. SMITH, Y. GUISEZ, R. DEVOS & P. BURN. 1995. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549.
17. PELLEYMOUNTER, M. A., M. J. CULLEN, M. B. BAKER, R. HECHT, D. WINTERS, T. BOONE & F. COLLINS. 1995. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543.
18. WALDER, K., M. WILLET, P. ZIMMET & G. R. COLLIER. 1996. Ob gene expression and leptin levels in Israeli Sand Rats (Psammomys obesus). Biochim. Biophys. Acta. In press.
19. FREDERICH, R. C., A. HAMANN, S. ANDERSON, B. LOLLMANN, B. B. LOWELL & J. S. FUER. 1995. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat. Med. 1: 1311-1314.
20. FREDERICH, R. C, B. LÖLLMANN, A. HAMANN, A. NAPOLITANO-ROSEN, B. B. KAHN, B. B. LOWELL & J. S. FLIER. 1995. Expression of ob mRNA and its enclosed protein in rodents: impact of nutrition and obesity. J. Clin. Invest. 96: 1658-1663.
21. FUNAHASHI, T., I. SHIMOMURA, H. HIRAOKA, T. ARAI, M. TAKAHASHI, T. NAKAMURA et al. 1995. Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned rats. Biochem. Biophys. Res. Commun. 211: 469-475.
22. MAFFEI, M., H. FEI, G. H. LEE, C. DANI, P. LEROY, Y. ZHANG, eial. 1995. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proc. Natl. Acad. Sci. U.S.A. 92: 6957-6960.
23. MAFFEI, M., J. HALAAS, E. RAVUSSIN, R. E. PRATLEY, G. H. LEE, Y. ZHANG, H. FEI, R. LALLONE, S. RANGANATHAN, P. A. KERN & J. M. FRIEDMAN. 1995. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1: 1155-1161.
24. OGAWA, Y., H. MASUZAKI, N. ISSE, T. OKAZAKI, K. MORI, M. SHIGEMOTO, etal. 1995. Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats. J. Clin. Invest. 96: 1647-1652.
25. ZIMMET, P., A. HODGE, M. NICHOLSON, M. STATEN, M. DE COURTEN, J. MOORE, A. MORAWIECZKI, J. LUBINA, G. COLLIER, G. ALBERTI & G. DOWSE. 1996. Serum leptin concentration, obesity, and insulin resistance in Western Samoans: the expression of the "thrifty gene"? Br. Med. J. 313: 965-969.
26. ZIMMET, P. Z. & G. R. COLLIER. 1996. Of mice and (wo)men: the obesity (ob) gene, its product, leptin, and obesity. Med. J. Aust. 164: 393-394.
27. COLLIER, G. R., K. WALDER, P. LEWANDOWSKI, A. SANIGORSKI & P. ZIMMET. 1996. Does the "thrifty gene" cause leptin resistance? Submitted.
28. WALDER, K., P. LEWANDOWSKI, A. SANIGORSKI, S. LEE, P. ZIMMET & G. R. COLLIER. 1996. Leptin administration has no effect on food intake, body weight, or diabetic status in a multigenie model of obesity: Psammomys obesus. Submitted.
29. TARTAGUA, L. A., M. DEMBSKI, X. WENG, N. DENG, J. CULPEPPER, R. DEVOS, G. J. RICHARDS, L. A. CAMPFIELD, F. T. CLARK, J. DEEDS, C. MUIR, S. SANKER, A. MORIARTY, K. J. MOORE, J. S. SMUTKO, G. G. MAYS, E. A. WOOLF, C. A. MONROE & R. I. TEPPER. 1995. Identification and expression cloning of a leptin receptor, OB-R. Cell 83: 1263-1271.
30. LEE, G.-H., R. PROENCA, J. M. MONTEZ, K. M. CARROLL, J. G. DARVISHZADEH, J. I. LEE & J. M. FRIEDMAN. 1996. Abnormal splicing of the leptin receptor in diabetic mice. Nature 379: 632-635.
31. CHUA, S. C., JR., W. K. CHUNG, X. S. WU-PENG, Y. ZHANG, S.-M. Liu, L. TARTAGLIA & R. L. LEIBEL. 1996. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 271: 994-996.
32. PHILLIPS, M. S., Q. Lu, H. A. HAMMOND, V. DUGAN, P. J. HEY, C. T. CASKEY & J. F. HESS. 1996. Leptin receptor missense mutation in the fatty Zucker rat. Nat. Genet. 13: 18-19.
33. ZARJEVSKI, N., I. CUSIN, R. VETTOR, F. ROHNER-JEANRENAUD & B. JEANRENAUD. 1993. Chronic intracerebrovemricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity. Endocrinology 133: 1753-1758.
34. Qu, D., D. S. LUDWIG, S. GAMMELTOFT, M. PIPER, M. A. PELLEYMOUNTER, M. J. CULLEN, W. F. MATTHER, J. PRZYPEX, R. KANAREK & E. MARTALOS-FUER. 1996. A role for melanin concentrating hormone in the central regulation of feeding behavior. Nature 380: 243-246.
35. ERICKSON, J. C., K. E. CLEGG & R. D. PALMITER. 1996. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381: 415-418.
36. TURTON, M. D., D. O'SHEA, I. GUNN, S. A, BEAK, C. M. B. EDWARDS, K. MEERAN, S. J. CHOI, G. M. TAYLOR & S. R. BLOOM. 1996. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 389: 69-72.
37. STEPHENS,T. W., M. BASINSKI, P. K. BRISTOW,J. M. BUE-VALLESKEY, S. G. BURGETT, L. CRAFT, J. HALE, J. HOFFMANN, H. M. HSLUNG, A. KRIAUCIUNAS, W. MACKELLAR, P. R. ROSTECK, JR., B. SCHONER, D. SMITH, F. C. TINSLEY, X-Y. ZHANG & M. HEIMAN. 1995. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377: 530-532.
38. SMITH, F. J., L. S. CAMPFIELD, J. A. MOSCHERA, P. S. BAILON & P. BURN. 1996. Feeding inhibition by neuropeptide Y. Nature 382: 307.
39. SCHWARTZ, M. W., D. G. BASKIN, T. R. BUKOWSKI, J. L. KUIJPER, D. FOSTER, G. LASSER, D. E. PRUNKARD, D. PORTE, JR., S. C. WOODS, R. J. SEELEY & D. S. WEIGLE. 1996. Spec-ificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45: 531-535.
40. LEVIN, N., C. NELSON, A. GURNEY, R. VANDLEN & F. DE SAUVAGE. 1996. Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc. Natl. Acad. Sci. U.S.A. 93: 1726-1730.
41. AHIMA, R. S., D. PRABAKARAN, C. MANTZOROS, D. Qu, B. BLOWELL, E. MARATOS-FLIER & J. S. FUER. 1996. Role of leptin in the neuroendocrine response to fasting. Nature 382:250-252.