Immunobiology of childhood tuberculosis: A window on the ontogeny of cellular immunity

Journal of Pediatrics

Volumn 131, Issue 1 I, 1997, Pages 16-26

  Smith, S ^a   Jacobs, R F ^a   Wilson, C B ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD40 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 15; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTATION; CELLULAR IMMUNITY; CHILD; CHILDHOOD DISEASE; HUMAN; IMMUNOPATHOGENESIS; INFANT; INFECTION RISK; LUNG ALVEOLUS MACROPHAGE; MAJOR CLINICAL STUDY; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NEWBORN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; T LYMPHOCYTE ACTIVATION; TUBERCULOSIS;

EID: 0030670408     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3476(97)70120-3     Document Type: Article

References (132)

1. P Sudre G ten Dam A Kochi Tuberculosis: a global overview of the situation today Bull World Health Organ 70 1992 149 159
2. MC Raviglione DE Snider A Kochi Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic JAMA 273 1995 220 226
3. PJ Dolin MC Raviglione A Kochi Global tuberculosis incidence and mortality during 1990-2000 Bull World Health Organ 72 1994 213 220
4. Tuberculosis morbidity—United States 1995 MMWR Morb Mortal Wkly Rep 45 1996 365 370
5. DB Lewis CB Wilson Developmental immunology and role of host defenses in neonatal susceptibility to infection 4th ed JS Remington JO Klein Infectious diseases of the fetus and newborn infant 1995 WB Saunders Philadelphia 20 98
6. PG Holt Postnatal maturation of immune competence during infancy and childhood Pediatr Allergy Immunol 6 1995 59 70
7. RM Locksley CB Wilson Cell mediated immunity and its role in host defense 4th ed GL Mandell JE Bennett R Dolin Mandell, Douglas, Bennett’s principles and practice of infectious diseases 1995 Churchill Livingstone New York 102 148
8. MF Lipscomb DE Bice CR Lyons The regulation of pulmonary immunity Adv Immunol 59 1995 369 455
9. IA Orme P Anderson WH Boom T cell responses to Mycobacterium tuberculosis J Infect Dis 167 1993 1481 1497
10. PF Barnes RL Modlin JJ Ellner T cell responses and cytokines BR Bloom Tuberculosis: pathogenesis, protection and control 1994 ASM Press Washington (DC) 417 436
11. T Gedde-Dahl Tuberculosis infection in the light of tuberculin matriculation Am J Hyg 56 1952 130 214
12. PW Beaven An analysis of tuberculosis infection from birth to old age; its relationship to clinical tuberculosis and deaths from tuberculosis Dis Chest 17 1950 280 292
13. FJW Miller RME Scale MD Taylor Tuberculosis in children 1963 Little Brown Boston 73 78
14. JR Starke RF Jacobs J Jereb Resurgence of tuberculosis in children J Pediatr 120 1992 839 855
15. GW Comstock VT Livesay SF Woolpert The prognosis of a positive tuberculin reaction in childhood and adolescence Am J Epidemiol 99 1974 131 139
16. J Tortone A Chattas JS Myers Tuberculosis in children less than six years of age Arch Pediatr Adolesc Med [Am J Dis Child] 58 1939 92 101
17. M Brailey Mortality in tuberculin-positive infants Bull Johns Hopkins Hosp 59 1936 1 10
18. EM Lincoln The value of follow-up studies of children with primary tuberculosis Am Rev Tuberc 64 1951 499 507
19. DE Snider HL Rieder D Combs Tuberculosis in children Pediatr Infect Dis J 7 1988 271 278
20. G Hussey T Chisholm M Kibel Miliary tuberculosis in children: a review of 94 cases Pediatr Infect Dis J 10 1991 832 836
21. RL Nemir K Krasinski Tuberculosis in children and adolescents in the 1980s Pediatr Infect Dis J 7 1988 375 379
22. LE Davis KR Rastogi LC Lambert Tuberculous meningitis in the Southwest United States: a community-based study Neurology 43 1993 1775 1778
23. RL Nemir Perspectives in adolescent tuberculosis: three decades of experience Pediatrics 78 1986 399 405
24. CD Gaynor FX McCormack DR Voelker Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages J Immunol 155 1995 5343 5351
25. J Chan Y Xing RS Magliozzo Killing of virulent mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated macrophages J Exp Med 175 1992 1111 1122
26. J Chan SHE Kaufmann Immune mechanisms of protection BR Bloom Tuberculosis: pathogenesis, protection and control 1994 ASM Press Washington (DC) 392 399
27. C Nathan Q Xie Nitric oxide synthases: roles, tolls and controls Cell 78 1994 915 918
28. QN Myrvik ES Leake MJ Wright Disruption of phagosomal membranes of normal alveolar macrophages by the H37Rv strain of Mycobacterium tuberculosis Am Rev Resp Dis 129 1984 322 328
29. JA Armstrong P D’Arcy Hart Response of cultured macrophages to Mycobacterium tuberculosis , with observations on fusion of lysosomes with phagosomes J Exp Med 134 1971 713 740
30. AH Gordon P D’Arcy Hart MR Young Ammonia inhibits phagosome-lysosome fusion in macrophages Nature 286 1980 79 80
31. V Falcone EB Bassey A Toiolo Differential release of tumor necrosis factor-α from murine peritoneal macrophages stimulated with virulent and avirulent species of mycobacteria FEMS Immunol Med Microbiol 8 1994 232 255
32. Y Zhang M Doerfler TC Lee Mechanisms of stimulation of interleukin-1β and tumor necrosis factor-α by Mycobacterium tuberculosis components J Clin Invest 91 1993 2076 2083
33. ER Rhoades AM Cooper IA Orme Chemokine response in mice infected with Mycobacterium tuberculosis Infect Immun 63 1995 3871 3877
34. SA Fulton JM Johnsen SF Wolf Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis : role of phagocytosis Infect Immun 64 1996 2523 2531
35. B Beutler GE Grau Tumor necrosis factor in the pathogenesis of infectious diseases Crit Care Med 21 1993 S423 S434
36. V Kindler AP Sappino GE Grau The inducing role of tumor necrosis factor in the development of bactericidal granuloma during BCG infection Cell 56 1989 731 740
37. JL Flynn MM Goldstein J Chan Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice Immunity 2 1995 561 572
38. EA Filley HA Bull PM Dowd The effect of Mycobacterium tuberculosis on the susceptibility of human cells to the stimulatory and toxic effects of tumor necrosis factor Immunology 77 1992 505 509
39. CL Silva LH Faccioli Tumor necrosis factor (cachectin) mediates induction of cachexia by cord factor from mycobacteria Infect Immun 56 1988 3067 3071
40. JM Tramontana U Utaipat A Molloy Thalidomide treatment reduces tumor necrosis factor α production and enhances weight gain in patients with pulmonary tuberculosis Molec Med 1 1995 384 397
41. RM Steinman The dendritic cell system and its role in immunogenicity Ann Rev Immunol 9 1991 271 297
42. SHE Kaufmann Immunity to intracellular microbial pathogens Immunol Today 16 1995 338 342
43. MLH De Bruijn MR Jackson PA Petersen Phagocyte-induced antigen-specific activation of unprimed CD8 + T cells in vitro Eur J Immunol 25 1995 1274 1285
44. SA Porcelli RL Modlin CD1 and the expanding universe of T cell antigens J Immunol 55 1995 3710 3711
45. EM Beckmen MB Brenner MHC class I-like, class II-like and CD1 molecules: distinct roles in immunity Immunol Today 16 1995 349 351
46. IA Orme FM Collins Protection against Mycobacterium tuberculosis infection by adoptive immunotherapy J Exp Med 158 1983 74 83
47. SHE Kaufmann CH Ladel Role of T cell subsets in immunity against intracellular bacteria: experimental infections of knock-out mice with Listeria monocytogenes and Mycobacterium bovis BCG Immunobiol 191 1994 509 519
48. T Pedrazzini K Hug JA Louis Importance of L3T4 + and Lyt-2 + cells in the immunologic control of infection with Mycobacterium bovis strain Bacillus Calmette-Guerin in mice J Immunol 139 1987 2032 2037
49. F Logat MM Keraan SR Rees Cellular immunity in tuberculous pleural effusions: evidence of spontaneous lymphocyte proliferation and antigen-specific accelerated responses to purified protein derivative (PPD) Clin Exp Immunol 90 1992 215 218
50. SHE Kaufmann I Flesch Function and antigen recognition pattern of L3T4 + T-cell clones from Mycobacterium tuberculosis -immune mice Infect Immun 54 1986 291 296
51. JL Flynn MM Goldstein KJ Triebold Major histocompatability complex class-I restricted T cells are required for resistance to Mycobacterium tuberculosis infection Proc Natl Acad Sci U S A 89 1992 12013 12017
52. CT Morita EM Beckmann JF Bukowski Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells Immunity 3 1995 495 507
53. I Tsuyuguchi H Kawasumi C Ueta Increase of T-cell receptor γ/δ bearing T cells in cord blood of newborn babies obtained by in vitro stimulation with mycobacterial cord factor Infect Immun 59 1991 3053 3059
54. C Ueta I Tsuyuguchi H Kawasumi Increase of γ/δ T cells in hospital workers who are in close contact with tuberculosis patients Infect Immun 62 1994 5434 5441
55. CH Ladel C Blum A Dreher Protective role of γ/δ T cells in tuberculosis Eur J Immunol 25 1995 2877 2881
56. PF Barnes JS Abrams S Lu Patterns of cytokine production by mycobacterium-reactive human T-cell clones Infect Immun 61 1993 197 203
57. P Andersen D Askgaard L Ljungqvist T-cell proliferative response to antigens secreted by Mycobacterium tuberculosis Infect Immun 59 1991 1558 1563
58. IA Orme AD Roberts JP Griffin Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection J Immunol 151 1993 518 525
59. TR Mosmann RL Coffman TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Ann Rev Immunol 7 1989 145 173
60. BR Bloom RL Modlin P Salgame Stigma variations: observations on suppressor T cells and leprosy Ann Rev Immunol 10 1992 453 488
61. PF Barnes S Lu JS Abrams Cytokine production at the site of disease in human tuberculosis Infect Immun 61 1993 3482 3489
62. CF Nathan HW Murray ME Wiebe Identification of interferon-γ as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity J Exp Med 158 1983 670 689
63. HW Murray Interferon-gamma, the activated macrophage and host defense against microbial challenge Ann Intern Med 108 1988 595 608
64. M Denis Involvement of cytokines in determining resistance and acquired immunity in murine tuberculosis J Leukoc Biol 50 1991 495 501
65. SHE Kaufman IE Flesch The role of T cell-macrophage interactions in tuberculosis Springer Semin Immunopathol 10 1988 337 358
66. M Denis Killing of Mycobacterium tuberculosis within human monocytes: activation by cytokines and calcitrol Clin Exp Immunol 84 1991 200 206
67. DS Robinson S Ying IK Taylor Evidence for a Th1-like bronchoalveolar T-cell subset and predominance of interferon-gamma gene activation in pulmonary tuberculosis Am J Respir Crit Care Med 149 1994 989 993
68. MJ Newport CM Huxley S Huston A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection N Engl J Med 335 1996 1941 1949
69. E Jouanguy F Altare S Lamhamedi Interferon-γ-receptor deficiency in an infant with fatal Bacille-Calmette-Guérin infection N Engl J Med 335 1996 1956 1961
70. DM Frucht SM Holland Defective monocyte costimulation for IFN-γ production in familial disseminated Mycobacterium avium complex infection J Immunol 157 1996 411 416
71. IA Orme ES Miller AD Roberts T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection J Immunol 148 1992 189 195
72. T Mutis YE Cornelisse THM Ottenhoff Mycobacteria induce CD4 + T cells that are cytotoxic and display Th1-like cytokine secretion profile: heterogeneity in cytotoxic activity and cytokine secretion levels Eur J Immunol 23 1993 2189 2195
73. EM Beckman SA Porcelli CT Morita Recognition of a lipid antigen by CD1 restricted αβ + T cells Nature 372 1994 691 694
74. EM Lincoln The clinical picture of tuberculosis in children Arch Pediatr Adolesc Med [Am J Dis Child] 60 1940 371 383
75. JP Griffin IA Orme Evolution of CD4 T-cell subsets following infection of naive and memory immune mice with Mycobacterium tuberculosis Infect Immun 62 1994 1683 1690
76. AM Dannenberg Roles of cytotoxic delayed-type hypersensitivity and macro-phage-activating cell-mediated immunity in the pathogenesis of tuberculosis Immuno-biology 191 1994 461 473
77. H Muller S Kruger Immunohistochemical analysis of cell composition and in situ expression in HIV- and non-HIV associated tuberculosis lymphadenitis Immunobiology 191 1994 354 368
78. PA Seiling RL Modlin Cytokine patterns at the site of mycobacterial infection Immunobiology 191 1994 378 387
79. MF Geertma HR Broos MT Vanen Barselaar Lung surfactant suppresses oxygen-dependent bactericidal functions of human blood monocytes by inhibiting the assembly of the NADPH oxidase J Immunol 150 1993 2391 2400
80. TR Martin CR Rubens CB Wilson Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung J Infect Dis 157 1987 91 100
81. G Kurland ATW Cheung ME Miller The ontogeny of pulmonary defenses: alveolar macrophage function in neonatal and juvenile rhesus monkeys Pediatr Res 23 1988 293 297
82. BJ Zelig LS Neururkar JA Bellanti Chemotactic and candidacidal responses of rabbit alveolar macrophages during postnatal development and modulating roles of surfactant in these responses Infect Immun 44 1984 379 385
83. JC Jackson S Palmer CB Wilson Postnatal changes in lung phospholipids and alveolar macrophages in term newborn monkeys Respir Physiol 73 1988 289 300
84. L Marodi R Kapaszta DB Campbell Candidacidal mechanisms in the human neonate: impaired IFN-γ activation of macrophages in newborn infants J Immunol 153 1994 5643 5649
85. JB d’Ambola MP Sherman DP Tashkin H Gong Jr Human and rabbit newborn lung macrophages have reduced anti-candida activity Pediatr Res 24 1988 285 290
86. R Rahunathan ME Miller S Everett Phagocyte chemotaxis in the perinatal period J Clin Immunol 2 1982 242 246
87. RB Klein TJ Fischer SE Gard Decreased mononuclear and polymorphonuclear chemotaxis in human newborns, infants and young children Pediatrics 60 1977 467 472
88. JD Bullock AF Robertson JG Bodenender Inflammatory responses in the neonate reexamined Pediatrics 44 1969 58 61
89. WH Sheldon JB Caldwell The mononuclear cell phase of inflammation in the newborn Bull Johns Hopkins Hosp 112 1963 258 269
90. KR Schibler MS. Traulman KW Liechty Diminished transcription of interleukin-8 by monocytes from preterm neonates J Leukoc Biol 53 1993 339 403
91. 4 and interleukin-8 from human monocytes: neonates exhibit a diminished response J Infect Dis 172 1995 420 426
92. 1 , macro-phage inflammatory protein-1α, and interleukin-8 gene expression is lower in stimulated human neonatal compared with adult mononuclear cells Blood 84 1994 118 124
93. J Laver E Duncan M Abboud High levels of granulocyte and granulocyte macrophage colony stimulating factors in cord blood of normal full-term infants J Pediatr 116 1990 627 632
94. S Taylor YJ Bryson Impaired production of γ-interferon by newborn cells in vitro is due to a functionally immature macrophage J Immunol 134 1985 1493 1497
95. SE McKenzie J Kline SE Douglas Enhancement in vitro of the low interferon production of leukocytes from human newborn infants J Leukoc Biol 53 1993 691 696
96. S Chheda H Palkowetz DK Rassin AS Goldman Decreased interleukin-10 production by neonatal monocytes and T cells: relationship to decreased production and expression of tumor necrosis factor-α and its receptors Pediatr Res 3 1996 475 483
97. V Pillay N Savage H Laburn Interleukin-1 receptor antagonist in newborn babies and pregnant women Pflugers Arch 424 1993 549 551
98. DWC Hunt HI Huppertz HJ Jiang Studies of human cord blood dendritic cells: Evidence for functional immaturity Blood 84 1994 4333 4343
99. M Clerici L DePalma E Roilides Analysis of T helper and antigen-presenting cell functions in cord blood and peripheral blood leukocytes from healthy children of different ages J Clin Invest 91 1993 2829 2836
100. JP Ridge EJ Fuchs P Matzinger Neonatal tolerance revisited: turning on newborn T cells with dendritic cells Science 271 1996 1723 1726
101. DJ Nelson PG Holt Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local dendritic cells to activation signals J Immunol 155 1995 3517 3524
102. BAE Vanderkerckhove R Baccala D Jones Thymic selection of the human T cell vβ repertoire in SCID-hu mice J Exp Med 176 1992 1619 1624
103. PJ Doherty CM Roifman S Pan Expression of the human T cell receptor vβ repertoire Mol Immunol 28 1991 607 612
104. HP Fischer CEM Sharrock GS Panayi High frequency of cord blood lymphocytes against mycobacterial 65-kDa heat-shock protein Eur J Immunol 22 1992 1667 1669
105. K Pechhold D Wesch S Schondelmaier Primary activation of Vγ9-expressing δT cells by Mycobacterium tuberculosis J Immunol 152 1994 4984 4992
106. AN Akbar L Terry A Timms Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells J Immunol 140 1988 2171 2178
107. ME Sanders MW Makgoba SO Sharrow Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CD29, and Pgp-1) and have enhanced IFN-γ production J Immunol 141 1988 1401 1407
108. ME Sanders MW Makgoba SO Sharrow Human naive and memory T cells: reinterpretation of helper-inducer and suppresser-inducer subsets Immunol Today 9 1988 195 199
109. H Pirenne Y Aujard A Eljaafari Comparison of T cell functional changes during childhood with the ontogeny of CDw29 and CD45RA expression on CD4 + T cells Pediatr Res 32 1992 81 86
110. RJ Noelle CD40 and its ligand in host defense Immunity 4 1996 415 419
111. R Fuleihan D Ahern RS Geha Decreased expression of the ligand for CD40 in newborn lymphocytes Eur J Immunol 24 1994 1925 1938
112. S Nonoyama LA Penix CE Edwards Diminished expression of CD40 ligand by activated neonatal T cells J Clin Invest 95 1995 66 75
113. JB Splawalski J Nishioka Y Nishioka CD40 ligand is expressed and functional on activated neonatal T cells J Immunol 156 1996 119 127
114. SK Burchett L Corey KM Mohan Diminished interferon-γ and lymphocyte proliferation in neonatal and postpartum primary herpes simplex virus infection J Infect Dis 165 1992 813 818
115. S Ehlers KA Smith Differentiation of T cell lymphokine expression: the in vitro acquisition of T cell memory J Exp Med 173 1991 25 36
116. CB Wilson The ontogeny of T lymphocyte maturation and function J Pediatr 118 1991 S4 S9
117. CY Wu C Demeure M Kiniwa IL-12 induced the production of IFN-γ by neonatal human CD4 T cells J Immunol 151 1993 1938 1949
118. U Shu CE Demeure DG Byun Interleukin 12 exerts a differential effect on the maturation of neonatal and adult CD45RO CD4 T cells J Clin Invest 94 1994 1352 1358
119. A Durandy G De-Saint-Basile B Lisowska-Grospierre Undetectable CD40 ligand expression on T cells and low B cell responses to CD40 binding agonists in human newborns J Immunol 154 1995 1560 1568
120. L Frenkel YJ Bryson Ontogeny of phytohemagglutinin-induced gamma interferon by leukocytes of healthy infants and children: evidence for decreased production in infants younger than 2 months of age J Pediatr 111 1987 97 100
121. JA Byrne JL Butler MD Cooper Differential activation requirements for virgin and memory T cells J Immunol 141 1988 3249 3257
122. JR Starke KT Taylor-Watta Tuberculosis in the pediatric population of Houston, Texas Pediatrics 84 1989 28 35
123. JG Vallejo LT Ong JR Starke Clinical features, diagnosis and treatment of tuberculosis in infants Pediatrics 94 1994 1 7
124. I Ildirim N Sapan B Cavusolglu Comparison of BCG vaccination at birth and at third month of life Arch Dis Child 67 1992 80 82
125. SR Rosenthal E Loewinsohn ML Graham BCG vaccination against tuberculosis in Chicago Pediatrics 28 1961 622 664
126. LP Ormerod JM Garnett Tuberculin response after neonatal BCG vaccination Arch Dis Child 63 1988 1491 1492
127. R Menzies B Vissandjee Effect of Bacille-Calmette-Guérin vaccination on tuberculin reactivity Am Rev Respir Dis 145 1992 621 625
128. M Lifschita The value of tuberculin skin test as a screening test for tuberculosis among BCG-vaccinated children Pediatrics 36 1965 624 627
129. RL Sepulveda IM Heiba A King Evaluation of tuberculin reactivity in BCG-immunized siblings Am J Respir Crit Care Med 149 1994 620 624
130. V Vijayalakshmi S Kumar AL Kiran Optimum age of a child for BCG vaccination Indian Pediatr 31 1994 1497 1501
131. WM Sullender JL Miller LL Yasakawa Humoral and cell-mediated immunity in neonates with herpes simplex virus infection J Infect Dis 155 1987 28 37
132. DP Greenberg JM Lieberman SM Marcy Enhanced antibody responses in infants given different sequences of heterogeneous Haemophilus influenzae type b conjugate vaccines J Pediatr 126 1995 206 211