Thyrotropin-receptor and thyroid peroxidase-specific T cell clones and their cytokine profile in autoimmune thyroid disease

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 11, 1997, Pages 3655-3663

  Fisfalen, Maria Elena ^a   Palmer, Ellen M ^a   Van Seventer, Gijs A ^a   Soltani, Keyoumars ^a   Sawai, Yoshikuni ^a   Kaplan, Edwin ^a   Hidaka, Yoh ^a   Ober, Carole ^a   DeGroot, Leslie J ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b MC 3090 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; LYMPHOTOXIN; THYROID PEROXIDASE; THYROTROPIN RECEPTOR;

AMINO ACID ANALYSIS; ARTICLE; AUTOIMMUNITY; HASHIMOTO DISEASE; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LYMPHOCYTE CLONE; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0030670033     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.11.3655     Document Type: Article

References (38)

1. Mosmann TR, Coffman RL. 1989 Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv Immunol. 136:2348-2357 (review).
2. Paul WE, Seder RA. 1994 Lymphocytes responses and cytokines. Cell. 76:241-251 (review).
3. Del Prete GF, De Carli M, Almerigogna F, et al. 1993 Human IL-10 is produced by both type 1 helper (Th1), type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol. 150:353-360.
4. Romagnani S. 1994 Lymphokine production by human T cell in disease states. Annu Rev Immunol. 12:227-257 (review).
5. Gerosa F, Paganin C, Peritt D, et al. 1996 Interleukin-12 primes human CD4 and CDS T cell clones for high production of both interferon-g and interleukin-10. J Exp Med. 183:2559-2569.
6. Croft M, Carter L, Swain SL, Dutton RW. 1994 Generation of polarized antigen specific CDS effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokineprofiles. J Exp Med. 180:1715-1728.
7. Rocken M, Racke M, Shevach EM. 1996 IL-4-induced immune deviation as antigen- specific therapy for inflammatory autoimmune disease. Immunol Today. 17:225-231 (review).
8. Aebischer I, Stadler BM. 1996 TH1-TH2 cells in allergic responses: at the limits of a concept. Adv Immunol. 61:341-403 (review).
9. Fisfalen ME, De Groot LJ. 1995 Autoimmune thyroid disease: Hashimoto's thyroiditis and Graves' disease. In: Weintraub, BD, ed. Molecular endocrinol-ogy: basic concepts and clinical correlations. New York: Raven Press (review); pp 319-370.
10. Kawakami Y, Fisfalen ME, DeGroot LJ. 1992 Proliferative responses of PBMC from patients with AITD to synthetic peptide epitopes of human TPO. Autoimmunity. 13:17-26.
11. Fisfalen ME, Soliman M, Okamoto Y, Soltani K, DeGroot LJ. 1995 Proliferative responses of T-cells to thyroid antigens and synthetic thyroid peroxidase peptides in autoimmune thyroid disease. J Clin Endocrinol Metab. 80:1597-1604.
12. Okamoto Y, Yanagawa T, Fisfalen ME, DeGroot LJ. 1994 Proliferative responses of peripheral blood mononuclear cells from patients with Graves' disease to synthetic peptides epitopes of human thyrotropin receptor. Thyroid. 4:37-42.
13. Soliman M, Kaplan E, Yanagawa T, Hidaka Y, Fisfalen ME, DeGroot LJ. 1995 T cells recognize multiple epitopes in the human thyrotropin receptor extra-cellular domain. J Clin Endocrinol Metab. 80:905-914.
14. Fisfalen ME, DeGroot LJ, Quintans J, Franklin WA, Soltani K. 1988 Microsomal antigen-reactive lymphocyte lines and clones derived from thyroid tissue of patients with Graves' disease. J Clin Endocrinol Metab. 66:776-784.
15. Okamoto Y, Yanagawa T, Soliman M. 1993 T Cell reactivity to the extracellular domain of recombinant human TSH receptor. Proc 75th Annual Meeting of The Endocrine Society, Las Vegas, Nevada (Abstract 1924).
16. Houghten RA. 1985 General method for the rapid solid phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acid. Proc Natl Acad Sci USA. 82:5131-5135.
17. Palmer E, Van Seventer GA. 1995 Identification of human T helper subsets generated in vitro by secreted cytokine profiles and cell surface phenotype. J Cell Biochem [Suppl 21A] C2-361:126.
18. McLachlan SM, Rapoport B. 1989 Evidence for a potential common T cell epitope between human thyroid peroxidase and human thyroglobulin with implications for the pathogenesis of autoimmune thyroid disease. Autoimmunity. 5:101-106.
19. Fisfalen ME, Diaz M, Soliman M, Yanagawa T, Soltani K. 1993 The amino acid residue 114-126 on TPO, may be an immunodominant T cell epitope in AITD. 67th Annual Meeting of the American Thyroid Association, 1993, Tampa, Florida. Thyroid. 3[Suppl]:T-66.
20. Tandon N, Freeman M, Weetman AP. 1991 T cell responses to synthetic thyroid peroxidase peptides in autoimmune thyroid disease. Clin Exp Immunol. 86:56-60.
21. Ewins DL, Barnett PS, Ratanachaiyavong S, et al. 1992 Antigen-specific T cell recognition of affinity-purified and recombinant thyroid peroxidase in autoimmune thyroid disease. Clin Exp Immunol. 90:93-98.
22. Tandon N, Freeman MA, Weetman AP. 1992 T cell responses to synthetic TSH receptor peptides in Graves' disease. Clin Exp Immunol. 89:468-173.
23. Nagy EV, Morris JC, Burch HB, et al. 1995 Thyrotropin receptor T cell epitopes in autoimmune thyroid disease. Clin Immunol Immmunopathol. 75:117-124.
24. Dayan CM, Londie M, Corcoran AE, et al. 1991 Autoantigen recognition by thyroid-infiltrating T cells in Graves' disease. Proc Natl Acad Sci USA. 88:7415-7419.
25. Mullin RJ, Cohen SBA, Webb LMC, et al. 1995 Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr Virus-transformed B cells lines. J Clin Invest. 96:30-37.
26. Lehmann PV, Sercarz EE, Forsthuber, et al. 1993 Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunol Today. 14:203-208.
27. Matsuo H, Batocchi A-P, Hawke S, et al. 1995 Peptide-selected T cell lines from myastenia gravis patients and controls recognize epitopes that are not processed from whole acetylcholine receptor. J Immunol. 155:3683-3692.
28. Watson PF, Pickerill AP, Davies R, Weetman AP. 1994 Analysis of cytokine gene expression in Graves' disease. J Clin Endocrinol Metab. 79:335-360.
29. Paschke R, Schuppert F, Taton M, Velu T. 1994 Intrathyroidal cytokine gene expression profiles in autoimmune thyroiditis. J Endocrinol. 141:309-315.
30. Prete GF, Tiri A, Mariotti S, et al. 1987 Enhanced production of γ-interferon by thyroid-derived T cells clones from patients with Hashimoto's thyroiditis. Clin Exp Immunol. 69:323-331.
31. Del Prete GF, Tiri A, De Carli M, et al. 1989 High potential to tumor necrosis factor alpha (TNF-alpha) production of thyroid infiltrating T lymphocytes in Hashimoto's thyroiditis: a peculiar feature of destructive thyroid autoimmunity. Autoimmunity. 4:267-276.
32. + T-cells clones from autoimmune thyroid tissue cannot be classified according to their lymphokine production. Scand J Immunol. 32:433-440.
33. Hemmer B, Vergelli M, Calabresi P, et al. 1996 Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99). J Neurosci Res. 45:852-862.
34. Giordano C, Stassi G, De Maria R, et al. 1997 Potential involvement of fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science. 275:960-963.
35. Meeusen Els NT, Premier RR, Brandon MR. 1996 Tissue-specific migration of lymphocytes: a key role for Th1 and Th2 cells? Immunol Today. 17:421-424.
36. + Th1 cells pro-inflammatory or anti-inflammatory? The ratio of IL-10 to IFN-g or IL-2 determines their function. Int Immunol. 7:1287-1294.
37. Blanas E, Carbone FR, Allison J, et al. 1996 Induction of autoimmune diabetes by oral administration of autoantigen. Science. 274:1707-1709.
38. Genain CP, Abel K, Belmar N, Villenger F, et al. 1996 Late complications of immune deviation therapy in a nonhuman primate. Science. 274:2054-2056.