Modification of α-chain or γ-chain heme pocket polarity by Val(E11) → Thr substitution has different effects on the steric, dynamic, and functional properties of human recombinant hemoglobin. Deoxy derivatives

Journal of Biological Chemistry

Volumn 272, Issue 42, 1997, Pages 26271-26278

  Cupane, Antonio ^a,f   Leone, Maurizio ^a   Militello, Valeria ^a   Friedman, Fred K ^b   Koley, Aditya P ^b   Vasquez, Gregory B ^c   Brinigar, William S ^d   Karavitis, Michael ^e   Fronticelli, Clara ^e  

^a INFM   (Italy)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^d Temple University   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

OXYHEMOGLOBIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN CONFORMATION;

CARBON MONOXIDE; CRYSTALLOGRAPHY, X-RAY; HEME; HEMOGLOBINS; HUMANS; KINETICS; POINT MUTATION; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS; TEMPERATURE;

EID: 0030664768     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.42.26271     Document Type: Article

References (47)

1. Fermi, G., Perutz, M. F., Shaanan, B., and Fourme, R. (1984) J. Mol. Biol. 174, 159-174
2. Shaanan, B. (1983) J. Mol. Biol. 171, 31-59
3. Fronticelli, C., Pechik, I., Brinigar, W. S., Kowalczyk, J., and Gilliland, G. L. (1994) J. Biol. Chem. 269, 23965-23969
4. Rivetti, C., Mozzarelli, A., Rossi, G. L., Henry, E. R., and Eaton, W. A. (1993) Biochemistry 32, 2888-2906
5. Benesch, R. E., and Kwong, S. (1990) J. Biol. Chem. 265, 14881-14885
6. Nagai, K., and Thogersen, H. C. (1984) Nature 309, 810-813
7. Fronticelli, C., O'Donnell, J. K., and Brinigar, W. S. (1991) J. Protein Chem. 10, 495-501
8. Sanna, M. T., Razynska, A., Karavitis, M., Koley, A. P., Friedman, F. K., Russu, I. M., Brinigar, W. S., and Fronticelli, C. (1997) J. Biol. Chem. 272, 3478-3486
9. Case, D. A., and Karplus, M. (1979) J. Mol. Biol. 132, 353-358
10. Kottalam, J., and Case, D. A. (1988) J. Am. Chem. Soc. 110, 7690-7697
11. Mathews, A. J., Rohlfs, R. J., Olson, J. S., Tame, J., Renaud, J.-P., and Nagai, K. (1989) J. Biol. Chem. 264, 16573-16583
12. Fronticelli, C., Brinigar, W. S., Olson, J. S., Bucci, E., Gryczynski, Z., O'Donnell, J. K., and Kowalczyk, J. (1993) Biochemistry 32, 1235-1242
13. Pechik, I., Ji, X., Fidelis, K., Karavitis, M., Moult, J., Brinigar, W. S., Fronticelli, C., and Gilliland, G. L. (1996) Biochemistry 35, 1935-1945
14. Militello, V., Cupane, A., Leone, M., Brinigar, W. S., Lu, A. L., and Fronticelli, C. (1995) Proteins Struct. Funct. Genet. 22, 12-19
15. Smerdon, S. J., Dodson, G. G., Wilkinson, A. J., Gibson, Q. H., Blackmore, R. S., Carver, T. E., and Olson, J. S. (1991) Biochemistry 30, 6252-6260
16. Cordone, L., Cupane, A., Leone, M., and Vitrano, E. (1986) Biophys. Chem. 24, 259-275
17. Di Pace, A., Cupane, A., Leone, M., Vitrano, E., and Cordone, L. (1992) Biophys. J. 63, 475-484
18. Cupane, A., Leone, M., Vitrano, E., and Cordone, L. (1995) Eur. Biophys. J. 23, 385-398
19. Chan, C. K., and Page, J. B. (1983) J. Chem. Phys. 79, 5234-5250
20. Frauenfelder, H., Parak, F., and Young, R. D. (1988) Annu. Rev. Biophys. Biophys. Chem. 17, 451-479
21. Srajer, V., Schomacker, K. T., and Champion, P. M. (1986) Phys. Rev. Lett. 57, 6656-6670
22. Srajer, V., and Champion, P. M. (1991) Biochemistry 30, 7390-7402
23. Cupane, A., Leone, M., and Vitrano, E. (1993) Eur. Biophys. J. 21, 385-391
24. Marquardt, D. W. (1963) J. Soc. Ind. Appl. Math. 11, 431-441
25. Bangcharoenpaurpong, O., Schomacker, K. T., and Champion, P. M. (1984) J. Am. Chem. Soc. 106, 5688-5698
26. Spiro, T. G. (1983) in Iron Porphyrins (Lever, A. B. P. and Gray, H. B., eds) Part II, pp. 89-159, Addison-Wesley Publishing Co., Reading, MA
27. Markowitz, A., Robinson, R. C., Omata, Y., and Friedman, F. K. (1992) Anal. Instrum. 20, 213-221
28. Jones, T. A., Zou, J.-V., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A47, 110-119
29. Satow, Y., Cohen, G., Padlan, E. A., and Davies, D. R. (1986) J. Mol. Biol. 190, 593-604
30. Doster, W., Cusack, S., and Petry, W. (1989) Nature 337, 754-756
31. Parak, F., Knapp, E. W., and Kucheida, W. (1982) J. Mol. Biol. 161, 177-194
32. Loncharich, R. J., and Brooks, B. R. (1990) J. Mol. Biol. 215, 439-455
33. Melchers, B., Knapp, E. W., Parak, F., Cordone, L., Cupane, A., and Leone, M. (1996) Biophys. J. 70, 2092-2099
34. Cordone, L., Cupane, A., Leone, M., Vitrano, E., and Bulone, D. (1988) J. Mol. Biol. 199, 213-218
35. Ansari, A., Berendzen, J., Braunstein, D., Cowen, B. R., Frauenfelder, H., Hong, M. K., Iben, I. E. T., Johnson, J. B., Ormos, P., Sauke, T. B., Scholl, R., Schulte, A., Steinbach, P. J., Vittitow, J., and Young, R. D. (1987) Biophys. Chem. 26, 337-355
36. Leone, M., Cupane, A., Militello, V., and Cordone, L. (1994) Eur. Biophys. J. 23, 349-352
37. Cupane, A., Leone, M., Vitrano, E., Cordone, L., Hiltpold, U. R., Winterhalter, K. H., Yu, W., and Di Iorio, E. E. (1993) Biophys. J. 65, 2461-2472
38. Leone, M., Cupane, A., and Cordone, L. (1996) Eur. Biophys. J. 24, 117-124
39. Doyle, M. L., Lew, G., De Young, A., Kwiatkowski, L., Wierzba, A., Noble, R. W. and Ackers, G. K. (1992) Biochemistry 31, 8629-8639
40. Murray, L. P., Hofrichter, J., Henry, E. R., and Eaton, W. A. (1988) Biophys. Chem. 29, 63-76
41. Chu, A. H., and Ackers, G. K. (1981) J. Biol. Chem. 256, 1199-1205
42. Quillin, M. L., Arduini, R. M., Olson, J. S., and Phillips, G. N., Jr. (1993) J. Mol. Biol. 234, 140-155
43. Cameron, A. D., Smerdon, S. J., Wilkinson, A. J., Habash, J., Helliwell, J., Li, T., and Olson, J. S. (1993) Biochemistry 32, 13061-13070
44. Deleted in proof
45. Phillips, S. E. V. (1980) J. Mol. Biol. 142, 531-554
46. Hargrove, M. C., Whitaker, T., Olson, J. S., Vali, R. J., and Mathews, A. J. (1997) J. Biol. Chem. 272, 17385-17389
47. Gattoni, M., Boffi, A., Sarti, P., and Chiancone, E. (1996) J. Biol. Chem. 271, 10130-10136