Molecular mechanisms of experimental glomerulonephritis: An overview

Nephrology

Volumn 3, Issue SUPPL. 2, 1997, Pages s633-s637

  Couser, William G ^a,b   Nangaku, Masaomi ^a   Shankland, Stuart J ^a   Johnson, Richard J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

C5b 9; Complement; Glomerulonephritis; IgA nephropathy; Mesangial cells

Indexed keywords

PROCOAGULANT; TRANSFORMING GROWTH FACTOR BETA;

AUTOIMMUNITY; COMPLEMENT ACTIVATION; CONFERENCE PAPER; GLOMERULONEPHRITIS; GLOMERULOSCLEROSIS; HEMOLYTIC UREMIC SYNDROME; IMMUNE COMPLEX DISEASE; IMMUNOPATHOGENESIS; INFLAMMATION; MACROPHAGE FUNCTION; MESANGIUM CELL; MINIMAL CHANGE GLOMERULONEPHRITIS; PRIORITY JOURNAL; THROMBOCYTE FUNCTION; THROMBOTIC THROMBOCYTOPENIC PURPURA;

EID: 0030660390     PISSN: 13205358     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1797.1997.tb00276.x     Document Type: Conference Paper

References (54)

1. Couser WG. Pathogenesis of glomerulonephritis. Kidney Int. 1993; 44: S19-26.
2. Couser WG. Mediation of immune glomerular injury. J. Am. Soc. Nephrol. 1990; 1: 13-29.
3. Couser WG. Mechanisms of glomerular injury in immune complex glomerulonephritis (Nephrology Forum). Kidney Int. 1985; 28: 569-83.
4. Couser WG, Darby C, Salant DJ et al. Effect of antibody to glomerular basement membrane on protein excretion in the isolated perfused rat kidney. Am. J. Physiol. 1985; 249: F241-50.
5. Couser WG. Research opportunities and future directions in glomerular disease. Sem. Nephrol. 1993; 13: 457-71.
6. Mendrick DL, Rennke HG. Induction of proteinuria in the rat by a monoclonal antibody against SGP-115-107. Kidney Int. 1988; 33: 818-30.
7. Assmann KJM, Van Son JPHF, Dijkman HBPM, Koene RAP. A nephritogenic rat monoclonal antibody to mouse aminopeptidase-A. Induction of massive albuminuria after a single intravenous injection. J. Exp. Med. 1992; 175: 623-35.
8. Salant DJ, Natori Y, Shimizu F. Glomerular injury due to antibody alone. In: EG Nielson, WG Couser (eds). Immunologic Renal Diseases. PA, Lippincott-Raven Publishers, Philadelphia, 1997; 357-74.
9. Koyakma A, Fujisaki M, Koboyashi M, Igarashi M, Narita M. A glomerular permeability factor produced by human T cell hybridomas. Kidney Int. 1991; 40: 453-60.
10. Dantal J, Bigot E, Gogers W et al. Effect of plasma protein absorption on protein excretion in kidney transplant recipients with recurrent nephrotic syndrome. N. Engl. J. Med. 1994; 330: 7-14.
11. Savin VJ, Sharma R, Sharma M et al. Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis. N. Engl. J. Med. 1996; 334: 878-83.
12. Garin EH, Blanchard DK, Matsushima K, Djeu JY. IL-8 production by peripheral blood mononuclear cells in nephrotic patients. Kidney Int. 1994; 45: 1311-17.
13. Garin EH, West L, Blanchard K, Matsushima K, Djeu JY. Effect of lymphokines on 35 sulfate uptake by the glomerular basement membrane. Nephron 1995; 71: 442-7.
14. Couser WG. Glomerular injury induced by the C5b-9 membrane attack complex of complement. In: Nephrology, Tokyo, Springer-Verlag, 1991; 182-190.
15. Couser WG, Pruchno CJ, Schulze M. The role of C5b-9 in experimental membranous nephropathy. Nephrol. Dial. Transplant. 1991; (Suppl 1): 25-31.
16. Couser WG, Baker PJ, Adler S. Complement and the direct mediation of immune glomerular injury. Kidney Int. 1995; 28: 879-900.
17. Farquhar M, Saito A, Kerjaschki D, Orlando R. The Heymann nephritis antigenic complex: Megalin (gp330) and RAP. J. Am. Soc. Nephrol. 1995; 6: 35-47.
18. Salant DJ, Belok S, Madaio MP, Couser WG. A new role for complement in experimental membranous nephropathy in rats. J. Clin. Invest. 1980; 66: 1339-50.
19. Leenaerts PL, Hall BM, Van Damme BJ, Daha MR, Renterghem YF. Active Heymann nephritis in complement component C-6 deficient rats. Kidney Int. 1995; 47: 1604-14.
20. Baker PJ, Ochi RF, Schulze M, Johnson RF, Campbell C, Couser WG. Depletion of C-6 prevents development of proteinuria in experimental membranous nephropathy in rats. Am. J. Pathol. 1989; 135: 185-94.
21. Cybulsky A, Quigg R, Salant D. The membrane attack complex in complement-mediated glomerular epithelial cell injury: Formation and stability of C5b-9 and C5b-7 in rat membranous nephropathy. J. Immunol. 1986; 137: 1511-16.
22. Savin VJ, Johnson RJ, Couser WG. C5b-9 increases albumin permeability of isolated glomeruli in vitro. Kidney Int. 1994; 46: 382-7.
23. Kerjaschki D, Schulze M, Binder S. Transcellular transport and membrane insertion of the C5b-9 membrane attack complex of complement by glomerular epithelial cells in experimental membranous nephropathy. J. Immunol. 1989; 143: 546-52.
24. Hansch GM, Schieren G, Wagner C, Schonermark M. Immune damage to the mesangium: antibody- and complement-mediated stimulation and destruction of mesangial cells. J. Am. Soc. Nephrol. 1992; 2: S139-43.
25. Neale TJ, Ullrich R, Ojha P, Poscewski H, Verhoeven AJ, Kerjaschki D. Expression of a neutrophil respiratory burst cytochrome and reactive oxygen species in kidney glomeruli in association with proteinuria in passive Heymann nephritis. Proc. Natl. Acad. Sci. USA. 1993; 90: 3645-9.
26. Neale T, Ojha P, Exner M et al. Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen. J. Clin. Invest. 1994; 94: 1577-84.
27. McMillan JI, Riordan JW, Couser WG, Pollock AS, Lovett DH. Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase-9 with enhanced expression in a model of membranous nephropathy. J. Clin. Invest. 1996; 97: 1094-101.
28. O'Donoghue DJ, Darvill A, Ballardie W. Mesangial cell auto-antigens in immunoglobulin A nephropathy and Henoch-Schönlein Purpura. J. Clin. Invest. 1991; 88: 1522-30.
29. Tomino Y, Endoh M, Nomoto Y, Sakai H. Specificity of eluted antibody from renal tissues of patients with IgA nephropathy. Am. J. Kidney Dis. 1982; 1: 276-80.
30. Rits M, Hiemstra PS, Bazin H, Van Es LA, Voerman JP, Daha MR. Activation of rat complement by soluble and insoluble rat IgA immune complexes. Eur. J. Immunol. 1988; 18: 1873-80.
31. Rauterberg EW, Lieberknecht HM, Wingen AM, Ritz E. Complement membrane attack (MAC) in idiopathic IgA-glomerulonephritis. Kidney Int. 1987; 31: 820-9.
32. Yamamoto T, Wilson CB. Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int. 1987; 32: 514-25.
33. Brandt J, Pippin J, Schulze M et al. Role of the complement membrane attack complex (C5b-9) in mediating experimental mesangioproliferative glomerulonephritis. Kidney Int. 1996; 49: 335-43.
34. Wang MX, Walker RG, Kincaid-Smith P. Clinicopathologic associations of anti-endothelial cell antibodies in immunoglobulin A nephropathy and lupus nephritis. Am. J. Kidney Dis. 1993; 22: 378-86.
35. Nangaku M, Alpers CG, Pippin J. A new model of renal microvascular endothelial injury. Kidney Int. 1997; 52: 182-94.
36. Nangaku M, Pippin J, Shankland SJ, Johnson RJ, Couser WG. C5b-9 membrane attack complex mediates renal microvascular injury induced by antibody to glomerular endothelial cells. Kidney Int. 1997 (In press).
37. Morgan BP, Meri S. Membrane proteins that protect against complement lysis. Spring Sem. Immunopathol. 1994; 15: 369-96.
38. Nangaku M, Meek R, Pippin J et al. Transfected CD59 protects mesangial cells from injury induced by antibody and complement. Kidney Int. 1996; 50: 257-66.
39. Nangaku M, Quigg RJ, Shankland SJ, Okada N, Johnson RJ, Couser WG. Overexpression of Crry protects mesangial cells from complement mediated injury. J. Am. Soc. Nephrol. 1997; 8: 223-33.
40. Nishikage H, Baranyi L, Okada H et al. The role of a complement regulatory protein in rat mesangial glomerulonephritis. J. Am. Soc. Nephrol. 1995; 6: 234-42.
41. Johnson RJ, Klebanoff SJ, Couser WG. Neutrophils. In: EG Neilson, WG Couser (eds). Immunologic Renal Diseases. Lippincott-Raven Publishers, Philadelphia, 1997; 541-52.
42. Johnson RJ, Couser WG, Chi EY, Adler S, Klebanoff SJ. A new mechanism for glomerular injury: The myeloperoxidase-hydrogen peroxide-halide system. J. Clin. Invest. 1987; 79: 1379-87.
43. 2)-handle system in immune complex nephritis: Demonstration of in vivo iodination. Kidney Int. 1987; 32: 342-9.
44. Johnson RJ, Couser WG, Alpers C, Vissers M, Schulze M, Klebanoff SJ. The human neutrophil serine proteinases, elastase and cathepsin G, can mediate glomerular injury in vivo. J. Exp. Med. 1988; 168: 1169-74.
45. Johnson RJ, Alpers CE, Pritzi P, Schulze M, Baker PJ, Couser WG. Platelets mediate neutrophil-dependent immune complex nephritis in the rat. J. Clin. Invest. 1988; 82: 1225-35.
46. Danoff TM, Nielson EG. The Role of Chemoattractants in Renal Disease. In: EG Niclson, WG Couser (Eds). Immunologic Renal Diseases. Lippincott-Raven Publishers, Philadelphia, 1997; 495-512.
47. Floege J, Rees AJ. Growth factors and cytokines. In: EG Nielson, WG Couser (eds). Immunologic Renal Diseases. Lippincott-Raven Publishers, Philadelphia, 1997; 415-52.
48. Bolton WK. Mechanisms of glomerular injury: injury mediated by sensitized lymphocytes. Semin. Nephrol. 1991; 11: 285-93.
49. Rovin BH, Schreiner GF. Cell-mediated immunity in glomerular disease. Ann. Rev. Med. 1991; 42: 25-33.
50. Rocklin R, Lewis E, David J. In vitro evidence for cellular hypersensitivity to glomerular basement membrane antigens in human glomerulonephritis. N. Engl. J. Med. 1970; 283: 497-501.
51. Dixon FJ. What are sensitized cells doing in glomerulonephritis? N. Engl. J. Med. 1970; 283: 536-7.
52. Bolton WK, Chandra M, Tyson TM, Kirkpatrick PR, Sadovnic MJ, Sturgill BC. Transfer of experimental glomerulonephritis in chickens by mononuclear cells. Kidney Int. 1988; 34: 598-610.
53. Rennke HG, Klein PS, Sandstrom DJ, Mendrick DL. Cell-mediated immune injury in the kidney: Acute nephritis induced in the rat by azobenzenearsonate. Kidney Int. 1994; 45: 1044-56.
54. Brouwer E, Huitema MG, Klot PA et al. Anti-myeloperoxidase associated proliferative glomerulonephritis: an animal model. J. Exp. Med. 1993; 177: 905-12.