The use, and misuse, of exogenous endothelial-derived vasodilators in acute respiratory failure

Intensive Care Medicine

Volumn 23, Issue 11, 1997, Pages 1110-1118

  Dinh Xuan, A T ^a   Brunet, F ^a   Dhainaut, J F ^a  

^a Cochin University Hospital ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALMITRINE; NITRIC OXIDE; PROSTACYCLIN; PROSTAGLANDIN E1; VASODILATOR AGENT;

ACUTE RESPIRATORY FAILURE; ADULT RESPIRATORY DISTRESS SYNDROME; DRUG EFFICACY; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LUNG ARTERY PRESSURE; LUNG GAS EXCHANGE; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; POSITIVE END EXPIRATORY PRESSURE; REVIEW; SIDE EFFECT;

ACUTE DISEASE; HUMANS; NITRIC OXIDE; PULMONARY GAS EXCHANGE; RESPIRATORY INSUFFICIENCY; VASODILATOR AGENTS; VENTRICULAR FUNCTION, RIGHT;

EID: 0030657513     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050466     Document Type: Review

References (100)

1. Knaus WA (1996) The ongoing mystery of ARDS. Intensive Care Med 22: 517-518
2. Curzen NP, Jourdan KB, Mitchell JA (1996) Endothelial modification of pulmonary vascular tone. Intensive Care Med 22: 596-607
3. Palevsky HI, Fishman AP (1991) The management of primary pulmonary hypertension. JAMA 265: 1014-1020
4. Rich S, Martinez J, Lam W, Levy PS, Rosen KM (1983) Reassessment of the effects of vasodilator drugs in primary pulmonary hypertension: guidelines for determining a pulmonary vasodilator response. Am Heart J 105: 119-127
5. Dinh-Xuan AT, Higenbottam TW (1996) Pulmonary vascular reactivity in acute respiratory failure of chronic obstructive pulmonary disease. In: Derenne JP, Whitelaw WA, Similowski T (eds) Acute respiratory failure of chronic obstructive pulmonary disease. Marcel Dekker, New York, pp 303-317
6. Dinh-Xuan AT, Brunet F, Dhainaut JF (1996) Inhaled nitric oxide: the light and shadow of a therapeutic breakthrough. In: Fink MP, Payen D (eds) Update in intensive care and emergency medicine. Volume 24. Role of nitric oxide in sepsis and ARDS. Springer, Berlin Heidelberg New York, pp 414-425
7. Halmagyi DFJ, Cotes JE (1959) Reduction in systemic blood oxygen as a result of procedures affecting the pulmonary circulation in patients with chronic pulmonary disease. Clin Sci 18: 475
8. Morgan JM, McCormack DG, Griffiths MJD, Morgan CJ, Barnes PJ, Evans TW (1991) Adenosine as a vasodilator in primary pulmonary hypertension. Circulation 84: 1145-1149
9. Haywood GA, Sneddon JF, Bashir Y, Jennison SH, Gray HH, McKenna WJ (1992) Adenosine infusion for the reversal of pulmonary vasoconstriction in biventricular failure: a good test but a poor therapy. Circulation 86: 896-902
10. Dupuy PM, Frostell CG (1997) Bronchial effects of nitric oxide. In: Zapol WM, Bloch KD (eds) Nitric oxide and the lung. Marcel Dekker, New York, pp 285-311
11. Adatia I, Wessel DL (1997) Diagnostic and therapeutic uses of inhaled nitric oxide in congenital heart disease. In: Zapol WM, Bloch KD (eds) Nitric oxide and the lung. Marcel Dekker, New York, pp 365-392
12. Dinh-Xuan AT (1992) Endothelial modulation of pulmonary vascular tone. Eur Respir J 5: 757-762
13. Dinh-Xuan AT (1993) Disorders of endothelium-dependent relaxation in pulmonary disease. Circulation 87[Suppl V]:V81-V87
14. Hampl V, Archer SL (1997) The role of endogenous nitric oxide in acute hypoxic pulmonary vasoconstriction. In: Zapol WM, Bloch KD (eds) Nitric oxide and the lung. Marcel Dekker, New York, pp 113-135
15. Leeman M (1996) Pulmonary vascular regulation by endogenous nitric oxide. In: Fink MP, Payen D (eds) Update in intensive care and emergency medicine. Volume 24. Role of nitric oxide in sepsis and ARDS. Springer, Berlin Heidelberg New York, pp 308-319
16. Martin W, Smith JA, White DG (1986) The mechanisms by which haemoglobin inhibits the relaxation of rabbit aorta induced by nitrovasodilators, nitric oxide or bovine retractor penis inhibitory factor. Br J Pharmacol 89: 563-571
17. Higenbottam TW, Pepke-Zaba J, Scott JP, Woolman P, Coutts C, Wallwork J (1988) Inhaled endothelium-derived relaxing factor in primary pulmonary hypertension (abstract). Am Rev Respir Dis 137[Suppl]:107
18. Stamler JS, Jaraki O, Osborne J et al. (1992) Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci USA 89: 7674-7677
19. Rimar S, Gillis CN (1995) Site of pulmonary vasodilation by inhaled nitric oxide in the perfused lung. J Appl Physiol 78: 1745-1749
20. Allison RC, Rippe B, Prasad VR, Parker JC, Taylor AE (1989) Pulmonary vascular permeability and resistance measurements in control and ANTU-injured lungs. Am J Physiol 256:H1711-H1718
21. Benzing A, Geiger K (1994) Inhaled nitric oxide lowers pulmonary capillary pressure and changes longitudinal distribution of pulmonary vascular resistance in patients with acute lung injury. Acta Anaesthesiol Scand 38: 640-645
22. Frostell CG (1994) Acute lung injury and inhaled NO: the reduction of pulmonary capillary pressure has implications for lung fluid balance. Acta Anaesthesiol Scand 38: 623-624
23. Frostell CG, Fratacci MD, Wain JC Jr, Jones R, Zapol WM (1991) Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 83: 2038-2047
24. Roberts JD Jr, Polaner DM, Lang P, Zapol WM (1992) Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 340: 818-819
25. Kinsella JP, Neish SR, Shaffer E, Abman SH (1992) Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 340:819-820
26. Rozé JC, Storme L, Zupan V, Morville P, Dinh-Xuan AT, Mercier JC (1994) Echocardiographic investigation of inhaled nitric oxide in newborn babies with severe hypoxaemia. Lancet 344: 303-305
27. Abman SH, Griebel JL, Parker DK, Schmidt JM, Swanton D, Kinsella JP (1994) Acute effects of inhaled nitric oxide in children with severe hypoxemic respiratory failure. J Pediatr 124: 881-888
28. Pepke-Zaba J, Higenbottam TW, Dinh-Xuan AT, Stone D, Wallwork J (1991) Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 338:1173-1174
29. Sitbon O, Brenot F, Denjean A, et al (1995) Inhaled nitric oxide as a screening vasodilator agent in primary pulmonary hypertension: a dose-response study and comparison with prostacyclin. Am J Respir Crit Care Med 151: 384-389
30. Adnot S, Kouyoumdjian C, Defouilloy C, et al (1993) Hemodynamic and gas exchange responses to infusion of acetylcholine and inhalation of nitric oxide in patients with chronic obstructive lung disease and pulmonary hypertension. Am Rev Respir Dis 148: 310-316
31. Rossaint R, Falke K J, López FA, Slama K, Pison U, Zapol WM (1993) Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 328: 399-405
32. Gerlach H, Pappert D, Lewandowski K, Rossaint R, Falke KJ (1993) Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome. Intensive Care Med 19: 443-449
33. Gerlach H, Rossaint R, Pappert D, Falke KJ (1993) Time-course and dose-response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome. Eur J Clin Invest 23: 499-502
34. Bigatello LM, Hurford WE, Kacmarek RM, Roberts JD Jr, Zapol WM (1994) Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Anesthesiology 80: 761-770
35. Puybasset L, Rouby JJ, Mourgeon E, et al (1994) Inhaled nitric oxide in acute respiratory failure: dose-response curves. Intensive Care Med 20: 319-327
36. Puybasset L, Rouby JJ, Mourgeon E, et al (1994) Inhaled nitric oxide reverses the increase in pulmonary vascular resistance induced by permissive hypercapnia in patients with acute respiratory distress syndrome. Anesthesiology 80: 1254-1267
37. Puybasset L, Rouby JJ, Mourgeon E, et al (1995) Factors influencing cardiopulmonary effects of inhaled nitric oxide in acute respiratory failure. Am J Respir Crit Care Med 152: 318-328
38. Levy B, Bollaert PE, Bauer P, et al (1994) Early use of inhaled nitric oxide associated with therapeutic optimization in severe adult respiratory distress syndrome (abstract). Am J Respir Crit Care Med 149[Suppl]:A425
39. Fierobe L, Brunet F, Dhainaut JF, et al (1995) Effect of inhaled nitric oxide on right ventricular function in adult respiratory distress syndrome. Am J Respir Crit Care Med 151: 1414-1419
40. Rossaint R, Slama K, Steudel W, et al (1995) Effects of inhaled nitric oxide on right ventricular function in severe acute respiratory distress syndrome. Intens Care Med 21: 197-203
41. Mira JP, Monchi M, Brunet F, Fierobe L, Dhainaut JF, Dinh-Xuan AT (1994) Lack of efficacy of inhaled nitric oxide in ARDS (letter). Intens Care Med 20: 532
42. Monchi M, Fierobe L, Mira JP, et al (1994) Predictive factors of inhaled nitric oxide inefficiency in ARDS patients (abstract). Am J Respir Crit Care Med 149[Suppl]:A423
43. Roupie E, Wysocki M, Langeron O, et al (1994) Effects of inhaled nitric oxide on oxygenation and hemodynamic parameters in the acute respiratory distress syndrome: responders versus non responders (abstract). Am J Respir Crit Care Med 149 [Suppl]: A424
44. Samama CM, Diaby M, Fellahi JL, et al (1995) Inhibition of platelet aggregation by inhaled nitric oxide in patients with acute respiratory distress syndrome. Anesthesiology 83: 56-65
45. Lundin S, Nathorst Westfelt U, Stenqvist O, et al (1996) Response to nitric oxide inhalation in early acute lung injury. Intens Care Med 22: 728-734
46. Payen DM, Gatecel C, Plaisance P (1993) Almitrine effect on nitric oxide inhalation in adult respiratory distress syndrome (letter). Lancet 341: 1664
47. Wysocki M, Delclaux C, Roupie E, et al (1994) Additive effects on gas exchange of inhaled nitric oxide and intravenous almitrine bismesylate in the adult respiratory distress syndrome. Intens Care Med 20: 254-259
48. Page Y, Bertrand M, Page D, et al (1994). Effects of inhaled nitric oxide in ARDS patients are variable and may be enhanced by almitrine (abstract). Am J Respir Crit Care Med 149[Suppl]:A426
49. Lu Q, Mourgeon E, Law-Koune JD, et al (1995) Dose-response curves of inhaled nitric oxide with and without intravenous almitrine in nitric oxide-responding patients with acute respiratory distress syndrome. Anesthesiology 83: 924-943
50. Walthers FJ, Benders M, Leighton JO (1992) Persistent pulmonary hypertension in premature neonates with severe respiratory distress syndrome. Pediatrics 90: 899-904
51. Pison U, López FA, Heidelmeyer CF, Rossaint R, Falke KJ (1993) Inhaled nitric oxide reverses hypoxic pulmonary vasoconstriction without impairing gas exchange. J Appl Physiol 74: 1287-1292
52. Mélot C, Naeije R, Rothschild T, Mertens P, Mols P, Hallemans R (1983) Improvement in ventilation-perfusion matching by almitrine in COPD. Chest 83: 528-533
53. Langer M, Mascheroni D, Marcolin R, Gattinoni L (1988) The prone position in ARDS patients: a clinical study. Chest 94: 103-107
54. Ryan DW, Pelosi P (1996) The prone position in acute respiratory distress syndrome. Br Med J 312: 860-861
55. Jolliet P, Bulpa P, Ricou B, Ritz M, Chevrolet JC (1996) Additive effects of prone position ventilation, nitric oxide and almitrine bismesylate in ARDS (abstract). Am J Respir Crit Care Med 153[Suppl 11]:A12
56. Radermacher P, Santak B, Wüst HJ, Tarnow J, Falke KJ (1990) Prostacyclin and right ventricular functions in patients with pulmonary hypertension associated with ARDS. Intens Care Med 16: 227-232
57. 1 in the adult respiratory distress syndrome: benefit for pulmonary hypertension and cost for pulmonary gas exchange. Am Rev Respir Dis 139: 106-116
58. Walmrath D, Schneider T, Pilch J, Grimminger F, Seeger W (1993) Aerosolised prostacyclin in adult respiratory distress syndrome. Lancet 342: 961-962
59. 2 aerosol versus nitric oxide for selective pulmonary vasodilation in hypoxic pulmonary vasodilation in hypoxic pulmonary vasoconstriction. Eur Surg Res 25: 329-340
60. Walmrath D, Schneider T, Schermuly R, Olschewski H, Grimminger F, Seeger W (1996) Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome. Am J Respir Crit Care Med 153: 991-996
61. Walmrath D, Schneider T, Pilch J, Schermuly R, Grimminger F, Seeger W (1995) Effects of aerosolized prostacyclin in severe pneumonia: impact of fibrosis. Am J Respir Crit Care Med 151: 724-730
62. Curtis J, O'Neill JT, Pettett G (1993) Endotracheal administration of tolazoline in hypoxia-induced pulmonary hypertension. Pediatrics 92: 403-408
63. 1 in acute respiratory distress syndrome: a placebo-controlled, randomized, double-blind, multicenter trial. Crit Care Med 24: 10-15
64. Högman M, Frostell CG, Hedenström H, Hedenstierna G (1993) Inhalation of nitric oxide modulates adult human bronchial tone. Am Rev Respir Dis 148: 1474-1478
65. A/Q̊ inequalities in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 149: 1482-1487
66. Sibbald WJ, Driedger AA, Myers ML, Short AIK, Wells GA (1983) Biventricular function in the adult respiratory distress syndrome. Chest 84: 126-134
67. Brunet F, Dhainaut JF, Devaux JY, Huyghebaert MF, Villemant D, Monsallier JF (1988) Right ventricular performance in patients with acute respiratory failure. Intens Care Med 14: 474-477
68. Zapol WM, Snider MT (1977) Pulmonary hypertension in severe acute respiratory failure. N Engl J Med 296: 476-480
69. Radermacher P, Huet Y, Pluskwa F, et al (1988) Comparison of ketanserin and sodium nitroprusside in patients with severe ARDS. Anesthesiology 68: 152-157
70. Zwissler B, Welte M, Messmer K (1995) Effects of inhaled prostacyclin as compared with inhaled nitric oxide on right ventricular performance in hypoxic pulmonary vasoconstriction. J Cardiothorac Vasc Anesth 9: 283-289
71. Pavlovic M, Petkovic D, Cvetkovic M, et al (1995) The influence of prostacyclin on contractile properties of isolated right ventricle of rat heart. Experientia 51: 941-944
72. Young JD, Dyar OJ (1996) Delivery and monitoring of inhaled nitric oxide. Intensive Care Med 22: 77-86
73. Frostell CG (1996) Monitoring and safety of inhaled nitric oxide. In: Fink MP, Payen D (eds) Update in intensive care and emergency medicine. Volume 24. Role of nitric oxide in sepsis and ARDS. Springer, Berlin Heidelberg New York, pp 342-354
74. Fink MP, Payen D (1996) The role of nitric oxide in sepsis and ARDS: synopsis of a roundtable conference held in Brussels on 18-20 March 1995. Intensive Care Med 22: 158-165
75. Bult H, de Meyer GRY, Jordaens F, Herman AG (1991) Chronic exposure to exogenous nitric oxide may suppress its endogenous release and efficacy. J Cardiovasc Pharmacol 17[Suppl 3]S79-S82
76. Rogers NE, Ignarro LJ (1992) Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine. Biochem Biophys Res Commun 189: 242-249
77. Buga GM, Griscavage JM, Rogers NE, Ignarro LJ (1993) Negative feedback regulation of endothelial cell function by nitric oxide. Circ Res 73: 808-812
78. Assreuy J, Cunha FQ, Liew FY, Moncada S (1993) Feedback inhibition of nitric oxide synthase activity by nitric oxide. Br J Pharmacol 108: 833-837
79. Rengasamy A, Johns RA (1993) Regulation of nitric oxide synthase by nitric oxide. Mol Pharmacol 44: 124-128
80. Patel JM, Abeles AJ, Block ER (1996) Nitric oxide exposure and sulfhydryl modulation alter L-arginine transport in cultured pulmonary artery endothelial cells. Free Radie Biol Med 20: 629-637
81. Stamler JS (1994) Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 78: 931-936
82. Griseavage JM, Fukuto JM, Komori Y, Ignarro LJ (1994) Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. J Biol Chem 269: 21644-21649
83. Abou-Soud HM, Wang J, Rousseau DL, Fukuto JM, Ignarro LJ, Stuehr DJ (1995) Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis. J Biol Chem 270: 22997-23006
84. Ravichadran LV, Johns RA, Rengasamy A (1995) Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide. Am J Physiol 268:H2216-H2223
85. Patel JM, Block ER (1995) Sulfhydryl-disulfide modulation and the role of disulfide oxidoreductases in regulation of the catalytic activity of nitric oxide synthase in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 13: 352-359
86. Patel JM, Zhang J, Block ER (1996) Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity. Am J Respir Cell Mol Biol 14:410-419
87. Kiff RJ, Moss DW, Moncada S (1994) Effect of nitric oxide gas on the generation of nitric oxide by isolated blood vessels: implications for inhalation therapy. Br J Pharmacol 113: 496-498
88. Oka M, Ohnishi M, Takahashi H, et al (1996) Altered vasoreactivity in lungs isolated from rats exposed to nitric oxide gas. Am J Physiol 271:L419-L424
89. Petros A (1994) Down-regulation of endogenous nitric oxide production after prolonged administration (letter). Lancet 344:191
90. Miller OI, Tang SF, Keech A, Celermajer DS (1995) Rebound pulmonary hypertension on withdrawal from inhaled nitric oxide (letter). Lancet 346: 51-52
91. Lavoie A, Hall JB, Olson DM, Wylam ME (1996) Life-threatening effects of discontinuing inhaled nitric oxide in severe respiratory failure. Am J Respir Crit Care Med 153: 1985-1987
92. Zapol WM, Rimar S, Gillis CN, Marletta M, Bosken CH (1994) Nitric oxide and the lung. Am J Respir Crit Care Med 149: 1375-1380
93. Kurrek MM, Castillo L, Bloch KD, Tannenbaum SR, Zapol WM (1995) Inhaled nitric oxide does not alter endotoxin-induced nitric oxide synthase activity during rat lung perfusion. J Appl Physiol 79: 1088-1092
94. Stamler JS, Singel DJ, Loscalzo J (1992) Biochemistry of nitric oxide and its redox-activated forms. Science 258: 1898-1902
95. Nathan CF (1992) Nitric oxide as a secretory product of mammalian cells. FASEB J 6: 3051-3064
96. Henry Y, Lepoivre M, Drapier JC, Ducrocq C, Boucher JL, Guissani A (1993) EPR characterization of molecular targets for NO in mammalian cells and organelles. FASEB J 7: 1124-1134
97. Matalon S, DeMarco V, Haddad IY, et al (1996) Inhaled nitric oxide injures the pulmonary surfactant system of lambs in vivo. Am J Physiol 270:L273-L280
98. Högman M, Frostell CG, Arnberg H, Hedenstierna G (1993) Bleeding time prolongation and NO inhalation (letter). Lancet 341: 1664-1665
99. Quinn AC, Vallance P (1993) Inhaled nitric oxide-from pollutant to patent. Eur J Clin Invest 23: 445-447
100. Dellinger RP, Zimmerman JL, Hyers TM, et al (1996) Inhaled nitric oxide in ARDS: preliminary results of a multicenter clinical trial (abstract). Crit Care Med 24[Suppl]:A29