Response to nitric oxide inhalation in early acute lung injury

Intensive Care Medicine

Volumn 22, Issue 8, 1996, Pages 728-734

  Lundin, S ^a   Nathorst Westfelt, U ^a   Stenqvist, O ^a   Blomqvist, H ^b   Lindh, A ^c   Berggren, L ^d   Arvidsson, S ^a   Rudberg, U ^b   Frostell, C G ^b  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b DANDERYD HOSPITAL   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d ÖREBRO MEDICAL CENTRE HOSPITAL   (Sweden)

Author keywords

Acute respiratory failure; Inhaled; Mechanical ventilation; Nitric oxide; Pulmonary artery pressure

Indexed keywords

NITRIC OXIDE;

ADULT; AGED; ARTERIAL OXYGEN SATURATION; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG ARTERY PRESSURE; LUNG GAS EXCHANGE; LUNG HEMODYNAMICS; LUNG INJURY; MALE; MULTICENTER STUDY;

EID: 10244225249     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01709513     Document Type: Article

References (20)

1. Ashbaugh DG, Bigelow DB, Petty TL, Levine BE (1967) Acute respiratory distress in adults. Lancet II:319-323
2. Moncada S, Palmer RMJ, Higgs EA (1991) Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43:109-142
3. Moncada S, Higgs A (1993) The Larginine - nitric oxide pathway. N Engl J Med 329:2002-2012
4. Frostell C, Fratacci MD, Wain JC, Jones R, Zapol WM (1991) Inhaled nitric oxide: A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 83: 2038-2047
5. Rossaint R, Falke KJ, López F, Slama K, Pison U, Zapol WM (1993) Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 328: 399-405
6. Gerlach H, Rossaint R, Pappert D, Falke KJ (1993) Time-course and dose-response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome. Eur J Clin Invest 23:499-502
7. Gerlach H, Pappert D, Lewandowski K, Rossaint R, Falke KJ (1993) Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome. Intensive Care Med 19:443-449
8. Bigatello LM, Hurford WE, Kacmarek RM, Roberts JD, Zapol WM (1994) Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Effects on pulmonary hemodynamics and oxygenation. Anesthesiology 80:761-770
9. Puybasset L, Rouby JJ, Mourgeon E, Stewart TE, Cluzel P, Arthaud M, Poète P, Bodin L, Korinek AM, Viars P (1994) Inhaled nitric oxide in acute respiratory failure: dose-response curves. Intensive Care Med 20:319-327
10. Murray JF, Matthay M, Luce J, Flick M (1988) An expanded definition of the adult respiratory distress syndrome. Am Rev Resp Dis 138:720-723
11. Knaus WA, Draper EA, Wagner DI, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818-829
12. Bernard GR, Luce JM, Sprung CL, Rinaldo JE, Tate RM, Sibbald WJ (1987) High dose corticosteroids in patients with the adult respiratory distress syndrome. N Engl J Med 317: 1565-1570
13. Stenqvist O, Kjelltoft B, Lundin S (1993) Evaluation of a new system for ventilatory administration of nitric oxide. Acta Anaesth Scand 37:687-691
14. Nathorst Westfelt U, Lundin S, Stenqvist O (1995) Safety aspects on delivery and monitoring of nitric oxide during mechanical ventilation. Acta Anaesthesiol Scand 40:302-310
15. Nunn JF (1993) Nunn's applied respiratory physiology, 4th edn. Butterworth-Heinemann, London, pp 178-179
16. Bone RC, Fisher CJ, Clemmer TP, Slotman GJ, Metz CA, Balk RA (1987) A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 317:653-658
17. Nathorst Westfelt U, Benthin G, Lundin S, Stenqvist O, Wennmalm Å (1995) Conversion of inhaled nitric oxide to nitrate in man. Br J Pharmacol 114: 1621-1624
18. Wysocki M, Delclaux C, Roupie E, Langeron O, Liu N, Herman B, Lemaire F, Brochard L (1994) Additive effect on gas exchange of inhaled nitric oxide and intravenous almitrine bismesylate in the adult respiratory distress syndrome. Intensive Care Med 20:254-259
19. Payen DM, Gatecel C, Plaisance P (1993) Almitrine effect on nitric oxide inhalation in adult respiratory distress syndrome. Lancet 341:1664
20. Gaston B, Drazen JM, Loscalzo J, Stamler JS (1994) The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 149:538-551