Inhibition of nitric oxide synthase expression by PPM-18, a novel anti-inflammatory agent, in vitro and in vivo

Biochemical Journal

Volumn 328, Issue 2, 1997, Pages 363-369

  Yu, Sheu M ^a   Wu, Jeng F ^a   Lin, Tzong L ^a   Kuo, Sheng C ^b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PPM 18; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; INTRAPERITONEAL DRUG ADMINISTRATION; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; SEPSIS; SEPTIC SHOCK; TOXICITY;

ANIMALIA;

EID: 0030656454     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3280363     Document Type: Article

References (33)

1. Moncada, S., Palmer, R. M. J. and Higgs, E. A. (1991) Pharmacol. Rev. 43, 109-142
2. Nathan, C. (1992) FASEB J. 6, 3051-3064
3. Dawson, T. M., Dawson, V. L. and Snyder, S. H. (1992) Ann. Neurol. 32, 297-311
4. Dinerman, J. L., Lowenstein, C. J. and Snyder, S. H. (1993) Circ. Res. 73, 217-222
5. Thiemermann, C., Szabo, C., Mitchell, J. A. and Vane, J. R. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 267-271
6. Szabo, C., Southan, G. J. and Thiemermann, C. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 12472-12476
7. Parrillo, J. E. (1993) New Engl. J. Med. 328, 1471-1477
8. Weisz, A., Oguchi, S., Cicatiello, L. and Esumi, H. (1994) J. Biol. Chem. 269, 8324-8333
9. Xie, Q. W., Cho, H. J., Calaycay, J., Mumford, R. A., Swiderek, K. M., Lee, T. D., Ding, A., Troso, T. and Nathan, C. (1992) Science 256, 225-228
10. Lowenstein, C. J., Alley, E. W., Raval, P., Snowman, A. M., Snyder, S. H., Russell, S. W. and Murphy, W. J. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 9730-9734
11. Grilli, M., Chiu, J. J. S. and Lenardo, M. J. (1993) Int. Rev. Cytol. 143, 1-62
12. Schreck, R., Meier, B., Mannel, D. N., Droge, W. and Baeuerle, P. A. (1992) J. Exp. Med. 175, 1181-1194
13. Mulsch, A., Schray-Utz, B., Mordvintacey, P. I., Hauschildt, S. and Busse, R. (1993) FEBS Lett. 321, 215-218
14. Sherman, M. P., Aeberhard, E. E., Wong, V. Z., Griscavage, J. M. and Ignarro, L. J. (1993) Biochem. Biophys. Res. Commun. 191, 1301-1308
15. Xie, Q. W., Kashiwabara, Y. and Nathan, C. (1994) J. Biol. Chem. 269, 4705-4708
16. Griscavage, J. M., Wilk, S. and Ignarro, L. J. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 3308-3312
17. Baeuerle, P. A. and Henkel, T. (1994) Annu. Rev. Immunol. 12, 141-179
18. Palombella, V. J., Rando, O. J., Goldberg, A. L. and Maniatis, T. (1994) Cell 78, 773-785
19. Rice, N. R. and Ernst, M. K. (1993) EMBO J. 12, 4685-4695
20. Lien, J. C., Huang, L. J., Wang, J. P., Teng, C. M., Lee, K. H. and Kuo, S. C. (1996) Chem. Pharm. Bull. 44, 1181-1187
21. Yu, S. M. (1994) Biochem. J. 303, 289-294
22. Schmidt, H. H. H. W., Warner, T. D., Nakane, M., Forster-Mann, U. and Murad, F. (1992) J. Pharmacol. Exp. Ther. 41, 615-624
23. Nunokawa, Y., Ishida, N. and Tanaka, S. (1993) Biochem Biophys. Res. Commun. 191, 89-94
24. Bredt, D. S. and Snyder, S. H. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 682-685
25. Dignam, J. D., Lebovitz, R. M. and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
26. Kleinert, H., Euchenhofer, C., Ihrig-Biedert, I. and Forstermann, U. (1996) Mol. Pharmacol. 49, 15-21
27. Henkel, T., Machleidt, T., Alkalay, I., Kranke, M., Ben-Neriah, Y. and Baeuerle, P. A. (1993) Nature (London) 365, 182-185
28. Shakov, A. N., Collart, M. A., Vassalli, P., Nedospasov, S. A. and Jongeneel, C. V. (1990) J. Exp. Med. 171, 35-47
29. Schreck, R., Rieber, P. and Baeuerle, P. A. (1991) EMBO J. 10, 2247-2258
30. Stamler, J. S., Simon, D. I., Osborne, J. A., Mullins, M. E., Jaraki, O., Michel, T., Singel, D. J. and Loscalzo, J. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 444-448
31. McCartney-Francis, N., Allen, J. B., Mizel, D. E., Albina, J. E., Xie, Q. W., Nathan, C. F. and Wahl, S. M. (1993) J. Exp. Med. 178, 749-754
32. Langrehr, J. M., Hoffman, R. A., Lancaster, J. R. and Simmons, R. L. (1993) Transplantation 55, 1205-1212
33. Vilcek, J. and Lee, T. H. (1991) J. Biol. Chem. 266, 7313-7316