Allopeptide-Specific T Cell Reactivity Altered by Peptide Analogs

Journal of Immunology

Volumn 158, Issue 1, 1997, Pages 48-54

  Colovai, Adriana I ^a   Liu, Zhuoru ^a   Harris, Paul E ^a   Cortesini, Raffaello ^b   Suciu Foca, Nicole ^a  

^a The New York Presbyterian Hospital   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; AMINO ACID; EPITOPE; HLA DR ANTIGEN; HLA-DRB1 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE; SUPPRESSOR FACTOR;

ARTICLE; BINDING COMPETITION; GENETICS; HUMAN; IMMUNITY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; T LYMPHOCYTE;

AMINO ACIDS; BINDING, COMPETITIVE; EPITOPES; HLA-DR ANTIGENS; HUMANS; IMMUNE TOLERANCE; IMMUNITY; ISOANTIGENS; MAJOR HISTOCOMPATIBILITY COMPLEX; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL; SUPPRESSOR FACTORS, IMMUNOLOGIC; T-LYMPHOCYTES;

EID: 0030639833     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Sherman, L. A., and S. Chattopadhyan. 1993. The molecular basis of allorecognition. Annu. Rev. Immunol. 11:385.
2. Bevan, M. J. 1984. High determinant density may explain the phenomenon of alloreactivity. Immunol. Today 5:128.
3. Rotzschke, O., K. Falk, S. Faath, and H.-G. Rammensee. 1991. On the nature of peptides involved in T cell alloreactivity. J. Exp. Med. 174:1059.
4. Mason, D. W., C. W. Pugh, and M. Webb. 1981. The rat mixed lymphocyte reaction: roles of a dendritic cell in intestinal lymph and T-cell subsets defined by monoclonal antibodies. Immunology 44:75.
5. Lechler, R. I., and J. R. Batchelor. 1982. Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells. J. Exp. Med. 155:31.
6. Steinman, R. M., and M. D. Witmer. 1978. Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. Immunology 75: 5132.
7. Larsen, C. P., S. C. Ritchie, T. C. Pearson, P. S. Linsley, and R. P. Lowry. 1992. Functional expression of the costimulatory molecule, B7/BB1, in murine dendritic cell populations. J. Exp. Med. 176:1215.
8. Lo, D., L. C. Burkly, R. A. Flavell, R. D. Palmiter, and R. L. Brinster. 1989. Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells. J. Exp. Med. 170:87.
9. Gaspari, A. A., M. K. Jenkins, and S. I. Katz. 1988. Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific TH1 clones. J. Immunol. 7:2216.
10. Bradley, J. A. 1996. Indirect T cell recognition in allograft rejection. Int. Rev. Immunol. 13:245.
11. Benichou, G., A. P. Takizawa, A. C. Olson, M. McMillan, and E. E. Sercarz. 1992. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J. Exp. Med. 175:305.
12. Fangmann, J., R. Dalchau, and J. W. Fabre. 1992. Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides. J. Exp. Med. 175:1521.
13. Liu, Z., A. I. Colovai, S. Tugulea, E. F. Reed, P. E. Fisher, D. Mancini, E. A. Rose, R. Cortesini, R. E. Michler, and N. Suciu-Foca. 1996. Indirect recognition of donor HLA-DR peptides in organ allograft rejection. J. Clin. Invest. 98:1150.
14. Auchincloss, H., Jr., R. Lee, S. Shea, J. S. Markowitz, M. J. Grusby, and L. H. Glimcher. 1993. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proc. Natl. Acad. Sci. USA 90:3373.
15. Lee, R. S., M. J. Grusby, L. H. Glimcher, H. J. Winn, and H. Auchincloss, Jr. 1994. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J. Exp. Med. 179:865.
16. + T cell-dependent antibody-mediated graft rejection. Immunol. Today 13:434.
17. Benichou, G., E. Fedoseyeva, P. V. Lehmann, C. A. Olson, H. M. Geysen, M. McMillian, and E. E. Sercarz. 1994. Limited T cell response to donor MHC peptides during allograft rejection. J. Immunol. 153:938.
18. Liu, Z., N. Braunstein, and N. Suciu-Foca. 1992. T cell recognition of allopeptides in context of syngeneic MHC. J. Immunol. 148:35.
19. Liu, Z., Y. K. Sun, Y. P. Xi, B. Hong, P. E. Harris, E. F. Reed, and N. Suciu-Foca. 1993. Limited usage of TCR Vβ genes by allopeptide-specific T cells. J. Immunol. 150:3180.
20. Liu, Z., P. Harris, A. I. Colovai, E. F. Reed, A. Maffei, and N. Suciu-Foca. 1996. Indirect recognition of donor MHC-class II antigens in human transplantation. Clin. Immunol. Immunopathol. 78:228.
21. Grassmann, R., B. Fleckenstein, and R. C. Desrosiers. 1994. Viral transformation of human T lymphocytes. Adv. Cancer Res. 63:211.
22. Scheirle, A. B., L. Takacs, F. Marin, and F. Sinigaglia. 1992. Peptide binding to soluble HLA-DR4 molecules produced by insect cells. J. Immunol. 148:2169.
23. Sharrock, C. E., E. Kaminski, and S. Mann. Limiting dilution analysis of human T cells: a useful clinical tool. 1990. Immunol. Today 11:281.
24. Krieger, J. I., R. W. Karr, H. M. Grey, W. Y. Yu, D. O'Sullivan, L. Batovsky, Z. L. Zheng, S. M. Colon, F. C. Gaeta, J. Sidney, M. Albertson, M. F. del Guercio, R. W. Chestnut, and A. Sette. 1991. Single amino acid changes in DR antigen define residues critical for peptide-MHC binding and T cell recognition. J. Immunol. 146:2331.
25. Jorgensen, J. L., P. A. Reay, E. W. Ehrich, and M. M. Davis. 1992. Molecular components of T-cell recognition. Annu. Rev. Immunol. 10:835.
26. Hammer, J., P. Vlsasnini, K. Tolba, D. Bolin, J. Higelin, B. Takacs, and F. Sinigaglia. 1993. Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell 74:97.
27. Evavold, B. D., J. Sloan-Lancaster, and P. M. Allen. 1993. Tickling the TCR: selective T cell functions stimulated by altered peptide ligands. Immunol. Today 14:602.
28. Critchfield, J. M., M. K. Racke, J. C. Zuniga-Pflucker, B. Cannella, C. S. Raine, J. Goverman, and M. J. Lenardo. 1994. T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science 263:1139.
29. Harris, P. E., Z. Liu, and N. Suciu-Foca. 1992. MHC class II binding of peptides derived from HLA-DR1. J. Immunol. 148:2169.
30. De Magistris, T. M., J. Alexander, M. Coggeshall, A. Altman, F. C. A. Gaeta, H. M. Grey, and A. Sette. 1992. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 68:625.
31. Smilek, D. E., D. C. Wraith, S. Hodgkinson, S. Dwivedy, L. Steinman, and H. O. McDevitt. 1991. A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 88:9633.
32. Wauben, M. H. M., C. J. P. Boog, R. van der Zee, I. Joosten, A. Schlief, and W. van Eden. 1992. Disease inhibition by major histocompatibility complex binding peptide analogues of disease-associated epitopes: more than blocking alone. J. Exp. Med. 176:667.
33. Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1993. Induction of T cell anergy by altered T cell receptor ligand on live antigen-presenting cells. Nature 363:156.
34. Sette, A., and G. Y. Ishioka. 1994. T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis. Eur. J. Immunol. 24:940.
35. Oldstone, M. B. A. 1987. Molecular mimicry and autoimmune disease. Cell 50:819.
36. Hagerty, D. T., and P. M. Allen. 1995. Intramolecular mimicry: identification and analysis of two-cross-reactive T cell epitopes within a single protein. J. Immunol. 155:2993.
37. Evavold, B. D., J. Sloan-Lancaster, K. J. Wilson, J. B. Rothbard, and P. M. Allen. 1995. Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands. Immunity 2:655.
38. Nanda, N. K., K. K. Arzoo, H. M. Geysen, A. Sette, and E. E. Sercarz. 1995. Recognition of multiple peptide cores by a single T cell receptor. J. Exp. Med. 182:531.
39. Windhagen, A., C. S Holz, P. Hollsberg, H. Fukaura, A. Sette, and D. A. Hafler. 1995. Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity 2:373.
40. Ashton-Rickardt, P. G., A. Bandeira, J. R. Delaney, L. Van Kaer, P. Pircher, R. M. Zinkernagel, and S. Tonegawa. 1994. Evidence for a differential avidity model of T cell selection in the thymus. Cell 76:651.
41. Liu, Z., Y. K. Sun, Y. P. Xi, P. E. Harris, and N. Suciu-Foca. 1992. T cell recognition of self human histocompatibility leukocyte antigens HLA-DR peptides in context of syngeneic HLA-DR molecules. J. Exp. Med. 175:1663.
42. Kuchroo, V. K., J. M. Greer, D. Kaul, G. Ishioka, A. Franco, A. Sette, R. A. Sobel, and M. B. Lees. 1994. A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire. J. Immunol. 153:3326.
43. Jameson, S. C., and M. J. Bevan. 1995. T cell receptor antagonists and partial agonists. Immunity 2:1.